First Dr visit after Braf/Mek drugs

I’m interested in when they’d use BRAF drugs also. I’m stage 4, but no internal organs detected yet (spread to multiple distant skin sites). As we were waiting for my BRAF results, my last onc said that, if it was positive, we’d probably look at targeted drugs as the next step. We also had a option of combo, since we had already learned that I was only getting opdivo in my trial. I switched recently to a new onc/clinic, and that guy’s suggestion right away was to try to combo (which agreed with my understanding of what the “traditional” next step would be). He said that, given I have essentially zero tumor burden, one of BRAF’s advantages wouldn’t be in play, and immunotherapy has generally longer term results, so it made sense to wait with BRAF. The new guy’s analysis made more sense to me, but wondering if the other idea has proponents also.

Targeted therapy with a BRAF/MEK combo (for BRAF positive patients) is often employed when there is a high tumor burden. We know that responses to immunotherapy tend to be more durable (lating) than targeted therapy (though there are those like RichardK on this forum who have been maintained on targeted therapy for years) but take time~ time that folks with a very high tumor burden may not have. Here is a report in which “choosing” your poison is discussed: http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2019/09/melanoma-patients-want-to-know-what-do.html

Melanoma always gotta be complicated – right????!!! Wishing all of you my best. Celeste