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mommydog
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mommydog

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      • November 17, 2011 at 3:15 am
      mommydog
      Participant

        My husband has been on this trial (GSK BRAF with randomized MEK) for over eight months now.  As of the last PET scan three weeks ago, his tumors had decreased in size by 81.7%.  Basically, there's very little left.  He is doing so well that he was given permission to go ahead with knee replacement surgery.  As far as we've heard, people are responding well to this treatment with few side effects.  There was a recent article in the SF Chronicle about a women in my husband's study who has been in the trial for 9 months and has had tumor reduction of 85%.  I think I'm just going to stop thinking about the other shoe dropping, because, for now, things are great.

        Deborah

        • November 17, 2011 at 3:15 am
        mommydog
        Participant

          My husband has been on this trial (GSK BRAF with randomized MEK) for over eight months now.  As of the last PET scan three weeks ago, his tumors had decreased in size by 81.7%.  Basically, there's very little left.  He is doing so well that he was given permission to go ahead with knee replacement surgery.  As far as we've heard, people are responding well to this treatment with few side effects.  There was a recent article in the SF Chronicle about a women in my husband's study who has been in the trial for 9 months and has had tumor reduction of 85%.  I think I'm just going to stop thinking about the other shoe dropping, because, for now, things are great.

          Deborah

          • November 17, 2011 at 3:15 am
          mommydog
          Participant

            My husband has been on this trial (GSK BRAF with randomized MEK) for over eight months now.  As of the last PET scan three weeks ago, his tumors had decreased in size by 81.7%.  Basically, there's very little left.  He is doing so well that he was given permission to go ahead with knee replacement surgery.  As far as we've heard, people are responding well to this treatment with few side effects.  There was a recent article in the SF Chronicle about a women in my husband's study who has been in the trial for 9 months and has had tumor reduction of 85%.  I think I'm just going to stop thinking about the other shoe dropping, because, for now, things are great.

            Deborah

            • May 22, 2012 at 5:24 pm
            mommydog
            Participant
              My husband was on the GSK b-raf trial with randomized MEK ( he had the highest dosage) and after being NED after nine months developed resistance to the drug or drugs, and developed several brain mets, had two craniotomies and has lost the use of the left side of his body.
              He is now having Yervoy infusions and is taking Zelboraf. Too early to see if anything is working. His onc at Ucsf had a patient who was not successful on the gsk braf inhibitor, but responded to zelboraf. Who knows.
              • May 22, 2012 at 5:24 pm
              mommydog
              Participant
                My husband was on the GSK b-raf trial with randomized MEK ( he had the highest dosage) and after being NED after nine months developed resistance to the drug or drugs, and developed several brain mets, had two craniotomies and has lost the use of the left side of his body.
                He is now having Yervoy infusions and is taking Zelboraf. Too early to see if anything is working. His onc at Ucsf had a patient who was not successful on the gsk braf inhibitor, but responded to zelboraf. Who knows.
                • May 22, 2012 at 5:24 pm
                mommydog
                Participant
                  My husband was on the GSK b-raf trial with randomized MEK ( he had the highest dosage) and after being NED after nine months developed resistance to the drug or drugs, and developed several brain mets, had two craniotomies and has lost the use of the left side of his body.
                  He is now having Yervoy infusions and is taking Zelboraf. Too early to see if anything is working. His onc at Ucsf had a patient who was not successful on the gsk braf inhibitor, but responded to zelboraf. Who knows.
                  • May 22, 2012 at 5:16 pm
                  mommydog
                  Participant
                    My husband has had two craniotomies. The surgeries themselves went well and he recovered easily and without much pain. However, since his tumors were located in and near the motor strip on the right side and had bled, he has lost the use of his left arm and leg.
                    Deborah
                    • May 22, 2012 at 5:16 pm
                    mommydog
                    Participant
                      My husband has had two craniotomies. The surgeries themselves went well and he recovered easily and without much pain. However, since his tumors were located in and near the motor strip on the right side and had bled, he has lost the use of his left arm and leg.
                      Deborah
                      • May 22, 2012 at 5:16 pm
                      mommydog
                      Participant
                        My husband has had two craniotomies. The surgeries themselves went well and he recovered easily and without much pain. However, since his tumors were located in and near the motor strip on the right side and had bled, he has lost the use of his left arm and leg.
                        Deborah
                        • September 8, 2011 at 12:24 am
                        mommydog
                        Participant

                          Not bad.  He has had some fevers and chills, at times quite severe, but those symptoms have subsided.

                          • September 8, 2011 at 12:24 am
                          mommydog
                          Participant

                            Not bad.  He has had some fevers and chills, at times quite severe, but those symptoms have subsided.

                            • September 7, 2011 at 10:03 pm
                            mommydog
                            Participant

                              Andrea Kantor

                              Clinical Research Coordinator

                              Cutaneous Oncology Program

                              UCSF Helen Diller Family Comprehensive Cancer Center

                              Investigational Trials Resource

                              Room A736| Box 1297

                              415.885.3855 /phone

                              415.514.6969 /fax

                              [email protected]

                               

                              try this, and good luck.

                              • September 7, 2011 at 10:03 pm
                              mommydog
                              Participant

                                Andrea Kantor

                                Clinical Research Coordinator

                                Cutaneous Oncology Program

                                UCSF Helen Diller Family Comprehensive Cancer Center

                                Investigational Trials Resource

                                Room A736| Box 1297

                                415.885.3855 /phone

                                415.514.6969 /fax

                                [email protected]

                                 

                                try this, and good luck.

                                • September 7, 2011 at 9:03 pm
                                mommydog
                                Participant

                                  Dave,

                                  The trial no. is NCT01072175.  It is sponsored by GSK and they are still recruiting.  According to the info on the gov. site, the trial is being conducted in several places, including Southern Ca.

                                  Here's a link to the info in clinicaltrials.gov

                                  http://clinicaltrials.gov/ct2/show/NCT01072175?term=melanoma+mek&spons=%22GlaxoSmithKline%22&spons_ex=Y&rank=4

                                   

                                  Let me know if there's any other informaiton that I can provide.

                                  Deborah

                                  • September 7, 2011 at 9:03 pm
                                  mommydog
                                  Participant

                                    Dave,

                                    The trial no. is NCT01072175.  It is sponsored by GSK and they are still recruiting.  According to the info on the gov. site, the trial is being conducted in several places, including Southern Ca.

                                    Here's a link to the info in clinicaltrials.gov

                                    http://clinicaltrials.gov/ct2/show/NCT01072175?term=melanoma+mek&spons=%22GlaxoSmithKline%22&spons_ex=Y&rank=4

                                     

                                    Let me know if there's any other informaiton that I can provide.

                                    Deborah

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