G-Samsa

I recently completed the Til treatment .  It was highly recommended to me when scans indicated progression after three years of stability with Ipi/Nivo.  I tried Traf/Mek first but it proved difficult to bear.   The Til treatment went well– a couple of tough weeks but then it's over.  The jury is still out on its effectiveness– but after a month there has been no more progression — and even some shrinkage in tumor size– so I'm hopeful.

My doctor told me that the hardest part of Til is getting into the trial..  It seems there are numerous points along the procedure timeline where you can be disqualified from continuing—even close infusion day.  So we had a couple of scares.  It's a lengthy process, and you need to wash out of the current treatment before they harvest a tumor…..so by the time you're actually infused it could be more than three months–which is really creepy when your progressing– Though in my case the progression helped a bit by producing a nice big tumor in a very accessible location…… You gotta look on the bright side.

I recently completed the Til treatment .  It was highly recommended to me when scans indicated progression after three years of stability with Ipi/Nivo.  I tried Traf/Mek first but it proved difficult to bear.   The Til treatment went well– a couple of tough weeks but then it's over.  The jury is still out on its effectiveness– but after a month there has been no more progression — and even some shrinkage in tumor size– so I'm hopeful.

My doctor told me that the hardest part of Til is getting into the trial..  It seems there are numerous points along the procedure timeline where you can be disqualified from continuing—even close infusion day.  So we had a couple of scares.  It's a lengthy process, and you need to wash out of the current treatment before they harvest a tumor…..so by the time you're actually infused it could be more than three months–which is really creepy when your progressing– Though in my case the progression helped a bit by producing a nice big tumor in a very accessible location…… You gotta look on the bright side.

I recently completed the Til treatment .  It was highly recommended to me when scans indicated progression after three years of stability with Ipi/Nivo.  I tried Traf/Mek first but it proved difficult to bear.   The Til treatment went well– a couple of tough weeks but then it's over.  The jury is still out on its effectiveness– but after a month there has been no more progression — and even some shrinkage in tumor size– so I'm hopeful.

My doctor told me that the hardest part of Til is getting into the trial..  It seems there are numerous points along the procedure timeline where you can be disqualified from continuing—even close infusion day.  So we had a couple of scares.  It's a lengthy process, and you need to wash out of the current treatment before they harvest a tumor…..so by the time you're actually infused it could be more than three months–which is really creepy when your progressing– Though in my case the progression helped a bit by producing a nice big tumor in a very accessible location…… You gotta look on the bright side.

In the current  round of Til trials at NIH is one specifically for those who have failed the PD-1. ( I believe it's opens to 64 people– not sure where they are today)  There are many hurdles—from the initial blood sample (sent fedex), through to the actual cell infusion—any of which can disqualify you.  There is also a washout period– which is scary in itself.  It's a good option regardless if your mel cooperates, and might be worth starting the ball rolling–at least until you've had your consultation and get a sense of how good a candidate they feel you are.

In the current  round of Til trials at NIH is one specifically for those who have failed the PD-1. ( I believe it's opens to 64 people– not sure where they are today)  There are many hurdles—from the initial blood sample (sent fedex), through to the actual cell infusion—any of which can disqualify you.  There is also a washout period– which is scary in itself.  It's a good option regardless if your mel cooperates, and might be worth starting the ball rolling–at least until you've had your consultation and get a sense of how good a candidate they feel you are.

In the current  round of Til trials at NIH is one specifically for those who have failed the PD-1. ( I believe it's opens to 64 people– not sure where they are today)  There are many hurdles—from the initial blood sample (sent fedex), through to the actual cell infusion—any of which can disqualify you.  There is also a washout period– which is scary in itself.  It's a good option regardless if your mel cooperates, and might be worth starting the ball rolling–at least until you've had your consultation and get a sense of how good a candidate they feel you are.

Hi — I have a lot of joint inflammation from these drugs, and as a result they have scheduled doses every other day.  I have moderate fever on the days I take the drug also.  The doctors suspect that the combined effect of the immunotherapy still circulating in me plus the combo is the cause and have suggested one 200mg ibuprofen  an hour before each dose — though I think every doctor has a remedy…

i have found the Ipi-Anti PD-1 combo much easier than this…..

Hi — I have a lot of joint inflammation from these drugs, and as a result they have scheduled doses every other day.  I have moderate fever on the days I take the drug also.  The doctors suspect that the combined effect of the immunotherapy still circulating in me plus the combo is the cause and have suggested one 200mg ibuprofen  an hour before each dose — though I think every doctor has a remedy…

i have found the Ipi-Anti PD-1 combo much easier than this…..

Hi — I have a lot of joint inflammation from these drugs, and as a result they have scheduled doses every other day.  I have moderate fever on the days I take the drug also.  The doctors suspect that the combined effect of the immunotherapy still circulating in me plus the combo is the cause and have suggested one 200mg ibuprofen  an hour before each dose — though I think every doctor has a remedy…

i have found the Ipi-Anti PD-1 combo much easier than this…..

Not that it know much about pharmacy-and this may be a small detail– but Tylenol on top of the combination drug Percocet is a lot of Tylenol.  My doctors have specifically prescribed Oxycodone (straight-up) to avoid excess Tylenol because of  potential liver toxicity.  I'd just be sure the right hand knows what the left is up to.

Not that it know much about pharmacy-and this may be a small detail– but Tylenol on top of the combination drug Percocet is a lot of Tylenol.  My doctors have specifically prescribed Oxycodone (straight-up) to avoid excess Tylenol because of  potential liver toxicity.  I'd just be sure the right hand knows what the left is up to.

Not that it know much about pharmacy-and this may be a small detail– but Tylenol on top of the combination drug Percocet is a lot of Tylenol.  My doctors have specifically prescribed Oxycodone (straight-up) to avoid excess Tylenol because of  potential liver toxicity.  I'd just be sure the right hand knows what the left is up to.