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First dose of Ipi… Yervoy.

Forums General Melanoma Community First dose of Ipi… Yervoy.

  • Post
    himynameiskevin
    Participant

      Hey everyone.
      There's not too much to update on, but it is another milestone in the journey, so I figured I'd let it be known for readers who still follow my posts. I just did my first dose of Ipilimumab/Yervoy. Although it's only been 5 hours, so far so good, hopefully any side effects will be minimal and I'll continue on with my future doses. And if I'm lucky it'll turn out all my cells from the ACT needed was one the last little *oomph* to clear these things out. Gosh that would be nice… We'll see, I'll keep you updated as I'm updated.

      Hey everyone.
      There's not too much to update on, but it is another milestone in the journey, so I figured I'd let it be known for readers who still follow my posts. I just did my first dose of Ipilimumab/Yervoy. Although it's only been 5 hours, so far so good, hopefully any side effects will be minimal and I'll continue on with my future doses. And if I'm lucky it'll turn out all my cells from the ACT needed was one the last little *oomph* to clear these things out. Gosh that would be nice… We'll see, I'll keep you updated as I'm updated.

      Thanks for the continuing concern and support.
      I'll talk to you soon.
      -Kevin

    Viewing 32 reply threads
    • Replies
        j.m.l.
        Participant

          Kevin, I am stage 3 mel. I am 1 week past 2nd infusion of ipi. side effects have been minimal so far. Some people say thats great. Some say that its better to have controlled side effects bec. that means that the immune syst. is revving up. Who really knows. Everyone is different. Some say that the side effects dont always hit until more wks have past. anyway, good luck.

          j.m.l.
          Participant

            Kevin, I am stage 3 mel. I am 1 week past 2nd infusion of ipi. side effects have been minimal so far. Some people say thats great. Some say that its better to have controlled side effects bec. that means that the immune syst. is revving up. Who really knows. Everyone is different. Some say that the side effects dont always hit until more wks have past. anyway, good luck.

            j.m.l.
            Participant

              Kevin, I am stage 3 mel. I am 1 week past 2nd infusion of ipi. side effects have been minimal so far. Some people say thats great. Some say that its better to have controlled side effects bec. that means that the immune syst. is revving up. Who really knows. Everyone is different. Some say that the side effects dont always hit until more wks have past. anyway, good luck.

              FormerCaregiver
              Participant

                Thanks for the update, Kevin. Hopefully Yervoy will give your immune system whatever it needs to have a complete response. As you have recently completed adoptive cell therapy (ACT), I feel that it should work well.

                Take care

                Frank from Australia

                FormerCaregiver
                Participant

                  Thanks for the update, Kevin. Hopefully Yervoy will give your immune system whatever it needs to have a complete response. As you have recently completed adoptive cell therapy (ACT), I feel that it should work well.

                  Take care

                  Frank from Australia

                  FormerCaregiver
                  Participant

                    Thanks for the update, Kevin. Hopefully Yervoy will give your immune system whatever it needs to have a complete response. As you have recently completed adoptive cell therapy (ACT), I feel that it should work well.

                    Take care

                    Frank from Australia

                    jim Breitfeller
                    Participant

                      Kevin,

                      Make sure your Oncologist is taking blood for (ALC) Absolute Lymphocyte count. If it doubles by week 7, most likely you will be a responder.

                      I wish you all the best

                       

                      Jimmy B

                        Laurie from maine
                        Participant

                          Hi Kevin,

                          Of course we wait to see your posts and hear how you are doing!!  You are a strong fighter and I look for your posts always.  Keep those posts coming.  Glad that so far so good with side effects.  My Fingers crossed and strong  prayers coming your way that this is what your body needed to help you kick that melanomat!!  Let us know.

                          laurie from maine

                          Laurie from maine
                          Participant

                            Hi Kevin,

                            Of course we wait to see your posts and hear how you are doing!!  You are a strong fighter and I look for your posts always.  Keep those posts coming.  Glad that so far so good with side effects.  My Fingers crossed and strong  prayers coming your way that this is what your body needed to help you kick that melanomat!!  Let us know.

                            laurie from maine

                            Laurie from maine
                            Participant

                              Hi Kevin,

                              Of course we wait to see your posts and hear how you are doing!!  You are a strong fighter and I look for your posts always.  Keep those posts coming.  Glad that so far so good with side effects.  My Fingers crossed and strong  prayers coming your way that this is what your body needed to help you kick that melanomat!!  Let us know.

                              laurie from maine

                            jim Breitfeller
                            Participant

                              Kevin,

                              Make sure your Oncologist is taking blood for (ALC) Absolute Lymphocyte count. If it doubles by week 7, most likely you will be a responder.

                              I wish you all the best

                               

                              Jimmy B

                              jim Breitfeller
                              Participant

                                Kevin,

                                Make sure your Oncologist is taking blood for (ALC) Absolute Lymphocyte count. If it doubles by week 7, most likely you will be a responder.

                                I wish you all the best

                                 

                                Jimmy B

                                willtolive
                                Participant

                                  Hi Kevin

                                  I´m so glad that you´re on Ipilimumab now. It could be your magic bullet. The (short) story of my wife, which I posted on June 24, three days after we got the results of 4 doses of Ipilimumab (3 mg pr.kg). She is now 4 months NED, a sensationel comeback in our fight against cancer! πŸ™‚ Good luck to you my friend. 

                                   

                                  Hi everyone

                                  I´ve been reading posts at this Bulletin Board for almost a year now. Some posts I have read with tears in my eyes, and some with joy. Here is our story (short version):

                                  I am the husband to a 39 year old woman from Denmark in Europe.

                                  In 2003 she had a mole removed from her thigh (Stage II). It contained melanoma-cells.

                                  In 2007 melanoma had spread to a lymph-node in her groin (Stage III). Surgery was needed.

                                  In 2008 melanoma relapsed in another lymph-node, surgery again.

                                  In 2009 melanoma hit us hard (Stage IV). It had spread to her lungs, one met in each lung. The size of the mets was 25 mm and 16 mm respectively. Surgery was fortunately possible.

                                  In October 2010 melanoma went back. This time there was multiples mets in each lung. About 5-6 mets in each lung. The biggest was 19 mm. It was unsurgeable, which was very hard to cope with.

                                  In November she began Interferon/Interleukin-2 treatment. It was tough beyond imagination. She had all the known sideeffects, and she was so bad during hospitalization. The midway PET/CT scans in January revealed that she was a responder! Scans showed that all the mets had become inactive or necrotic. Some mets had even shrunk a little bit. We were delighted, and she continued with the third and fourth series of Interferon/IL-2.

                                  February 15 we got the results of the next scan. We were optimistic because the midway scans was indeed promising. We were shocked when told that the melanoma had began to grow again. There was 2 active mets now. One big met, about 32 mm in diameter, in her right lung lightened up. In addiction there was a lot of fluid in the right lung membrane, and it probably contained melanoma-cells. All other mets was still inactive, except one, and our doctor feared that it would be only a matter of time, before the other mets would begin to grow again. We were devastated.

                                  Our doctor suggested Ipilimumab, and my wife started March 11, on the same day Japan was shaken by the huge earthquake. I watched it on TV while she was receiving the first dose of ipilimumab (3 mg/kg dose). I remember wishing that the drug was the earthquake of our lives…

                                  My wife have always been a positive and happy human being, no matter what challenges life would bring, she still truly believe that she could defeat this Melanoma Devil. She began consulting a Chinese doctor and received acupuncture twice a week. Beside this she trained 4-5 times a week, fitness and running. In these situations we talked about preparing your body to fight the cancer, with a "little" help from our friend, ipilimumab…

                                  She received 4 doses every third week and got a CT scan in June.

                                  Three days ago on June 21 we arrived to the hospital to talk with our doctor about the results of the CT scan. The time from the scans being done and to get the results is awful with a lot of anxiety, you guys all know… The scan showed that the 32 mm met in the right lung was completely GONE!!!!! The fluid was gone too, and the x-ray showed a nice healthy looking right lung. We were stunned. I hugged my wife with a lot of tears in my eyes. Our doctor was very delighted too. Ipilimumab had worked much better than expected. We had hoped for stabilization, maybe shrinkage, if we were lucky. But this???? Unbelievable. Some other small mets was still there but hasn´t grown in size in half a year, and our doctor said it very well could be necrotic tissue.

                                  This is where we stand now. We´re thrilled and delighted and so so happy. We have now dared to plan for more than a month πŸ™‚

                                  So this story is to all you Warriors out there, keep on fighting with believe and trust in your hearts. The path is very tough but the battle can be won, sooner or later. We´ll keep fighting this Devil.

                                   

                                  Kind regards

                                  willtolive 

                                   

                                  willtolive
                                  Participant

                                    Hi Kevin

                                    I´m so glad that you´re on Ipilimumab now. It could be your magic bullet. The (short) story of my wife, which I posted on June 24, three days after we got the results of 4 doses of Ipilimumab (3 mg pr.kg). She is now 4 months NED, a sensationel comeback in our fight against cancer! πŸ™‚ Good luck to you my friend. 

                                     

                                    Hi everyone

                                    I´ve been reading posts at this Bulletin Board for almost a year now. Some posts I have read with tears in my eyes, and some with joy. Here is our story (short version):

                                    I am the husband to a 39 year old woman from Denmark in Europe.

                                    In 2003 she had a mole removed from her thigh (Stage II). It contained melanoma-cells.

                                    In 2007 melanoma had spread to a lymph-node in her groin (Stage III). Surgery was needed.

                                    In 2008 melanoma relapsed in another lymph-node, surgery again.

                                    In 2009 melanoma hit us hard (Stage IV). It had spread to her lungs, one met in each lung. The size of the mets was 25 mm and 16 mm respectively. Surgery was fortunately possible.

                                    In October 2010 melanoma went back. This time there was multiples mets in each lung. About 5-6 mets in each lung. The biggest was 19 mm. It was unsurgeable, which was very hard to cope with.

                                    In November she began Interferon/Interleukin-2 treatment. It was tough beyond imagination. She had all the known sideeffects, and she was so bad during hospitalization. The midway PET/CT scans in January revealed that she was a responder! Scans showed that all the mets had become inactive or necrotic. Some mets had even shrunk a little bit. We were delighted, and she continued with the third and fourth series of Interferon/IL-2.

                                    February 15 we got the results of the next scan. We were optimistic because the midway scans was indeed promising. We were shocked when told that the melanoma had began to grow again. There was 2 active mets now. One big met, about 32 mm in diameter, in her right lung lightened up. In addiction there was a lot of fluid in the right lung membrane, and it probably contained melanoma-cells. All other mets was still inactive, except one, and our doctor feared that it would be only a matter of time, before the other mets would begin to grow again. We were devastated.

                                    Our doctor suggested Ipilimumab, and my wife started March 11, on the same day Japan was shaken by the huge earthquake. I watched it on TV while she was receiving the first dose of ipilimumab (3 mg/kg dose). I remember wishing that the drug was the earthquake of our lives…

                                    My wife have always been a positive and happy human being, no matter what challenges life would bring, she still truly believe that she could defeat this Melanoma Devil. She began consulting a Chinese doctor and received acupuncture twice a week. Beside this she trained 4-5 times a week, fitness and running. In these situations we talked about preparing your body to fight the cancer, with a "little" help from our friend, ipilimumab…

                                    She received 4 doses every third week and got a CT scan in June.

                                    Three days ago on June 21 we arrived to the hospital to talk with our doctor about the results of the CT scan. The time from the scans being done and to get the results is awful with a lot of anxiety, you guys all know… The scan showed that the 32 mm met in the right lung was completely GONE!!!!! The fluid was gone too, and the x-ray showed a nice healthy looking right lung. We were stunned. I hugged my wife with a lot of tears in my eyes. Our doctor was very delighted too. Ipilimumab had worked much better than expected. We had hoped for stabilization, maybe shrinkage, if we were lucky. But this???? Unbelievable. Some other small mets was still there but hasn´t grown in size in half a year, and our doctor said it very well could be necrotic tissue.

                                    This is where we stand now. We´re thrilled and delighted and so so happy. We have now dared to plan for more than a month πŸ™‚

                                    So this story is to all you Warriors out there, keep on fighting with believe and trust in your hearts. The path is very tough but the battle can be won, sooner or later. We´ll keep fighting this Devil.

                                     

                                    Kind regards

                                    willtolive 

                                     

                                    willtolive
                                    Participant

                                      Hi Kevin

                                      I´m so glad that you´re on Ipilimumab now. It could be your magic bullet. The (short) story of my wife, which I posted on June 24, three days after we got the results of 4 doses of Ipilimumab (3 mg pr.kg). She is now 4 months NED, a sensationel comeback in our fight against cancer! πŸ™‚ Good luck to you my friend. 

                                       

                                      Hi everyone

                                      I´ve been reading posts at this Bulletin Board for almost a year now. Some posts I have read with tears in my eyes, and some with joy. Here is our story (short version):

                                      I am the husband to a 39 year old woman from Denmark in Europe.

                                      In 2003 she had a mole removed from her thigh (Stage II). It contained melanoma-cells.

                                      In 2007 melanoma had spread to a lymph-node in her groin (Stage III). Surgery was needed.

                                      In 2008 melanoma relapsed in another lymph-node, surgery again.

                                      In 2009 melanoma hit us hard (Stage IV). It had spread to her lungs, one met in each lung. The size of the mets was 25 mm and 16 mm respectively. Surgery was fortunately possible.

                                      In October 2010 melanoma went back. This time there was multiples mets in each lung. About 5-6 mets in each lung. The biggest was 19 mm. It was unsurgeable, which was very hard to cope with.

                                      In November she began Interferon/Interleukin-2 treatment. It was tough beyond imagination. She had all the known sideeffects, and she was so bad during hospitalization. The midway PET/CT scans in January revealed that she was a responder! Scans showed that all the mets had become inactive or necrotic. Some mets had even shrunk a little bit. We were delighted, and she continued with the third and fourth series of Interferon/IL-2.

                                      February 15 we got the results of the next scan. We were optimistic because the midway scans was indeed promising. We were shocked when told that the melanoma had began to grow again. There was 2 active mets now. One big met, about 32 mm in diameter, in her right lung lightened up. In addiction there was a lot of fluid in the right lung membrane, and it probably contained melanoma-cells. All other mets was still inactive, except one, and our doctor feared that it would be only a matter of time, before the other mets would begin to grow again. We were devastated.

                                      Our doctor suggested Ipilimumab, and my wife started March 11, on the same day Japan was shaken by the huge earthquake. I watched it on TV while she was receiving the first dose of ipilimumab (3 mg/kg dose). I remember wishing that the drug was the earthquake of our lives…

                                      My wife have always been a positive and happy human being, no matter what challenges life would bring, she still truly believe that she could defeat this Melanoma Devil. She began consulting a Chinese doctor and received acupuncture twice a week. Beside this she trained 4-5 times a week, fitness and running. In these situations we talked about preparing your body to fight the cancer, with a "little" help from our friend, ipilimumab…

                                      She received 4 doses every third week and got a CT scan in June.

                                      Three days ago on June 21 we arrived to the hospital to talk with our doctor about the results of the CT scan. The time from the scans being done and to get the results is awful with a lot of anxiety, you guys all know… The scan showed that the 32 mm met in the right lung was completely GONE!!!!! The fluid was gone too, and the x-ray showed a nice healthy looking right lung. We were stunned. I hugged my wife with a lot of tears in my eyes. Our doctor was very delighted too. Ipilimumab had worked much better than expected. We had hoped for stabilization, maybe shrinkage, if we were lucky. But this???? Unbelievable. Some other small mets was still there but hasn´t grown in size in half a year, and our doctor said it very well could be necrotic tissue.

                                      This is where we stand now. We´re thrilled and delighted and so so happy. We have now dared to plan for more than a month πŸ™‚

                                      So this story is to all you Warriors out there, keep on fighting with believe and trust in your hearts. The path is very tough but the battle can be won, sooner or later. We´ll keep fighting this Devil.

                                       

                                      Kind regards

                                      willtolive 

                                       

                                        mombase
                                        Participant

                                          What an awesome an inspirational story. Thank you for sharing!

                                          Cristy, Stage IV

                                          mombase
                                          Participant

                                            What an awesome an inspirational story. Thank you for sharing!

                                            Cristy, Stage IV

                                            mombase
                                            Participant

                                              What an awesome an inspirational story. Thank you for sharing!

                                              Cristy, Stage IV

                                            JuleFL
                                            Participant
                                              Wishing you all the best, Kevin.

                                              Jule

                                              JuleFL
                                              Participant
                                                Wishing you all the best, Kevin.

                                                Jule

                                                JuleFL
                                                Participant
                                                  Wishing you all the best, Kevin.

                                                  Jule

                                                  mombase
                                                  Participant

                                                    Fantastic, Kevin! May the side effects stay minimal and the outcome maximum!!

                                                    Cristy, Stage IV

                                                    mombase
                                                    Participant

                                                      Fantastic, Kevin! May the side effects stay minimal and the outcome maximum!!

                                                      Cristy, Stage IV

                                                      mombase
                                                      Participant

                                                        Fantastic, Kevin! May the side effects stay minimal and the outcome maximum!!

                                                        Cristy, Stage IV

                                                        triciad
                                                        Participant

                                                          Kevin,

                                                          I'm sending prayers your way that this will be the magic treatment for you.  Keep up the positive attitude…we're all pulling for you!

                                                          Tricia

                                                          triciad
                                                          Participant

                                                            Kevin,

                                                            I'm sending prayers your way that this will be the magic treatment for you.  Keep up the positive attitude…we're all pulling for you!

                                                            Tricia

                                                            triciad
                                                            Participant

                                                              Kevin,

                                                              I'm sending prayers your way that this will be the magic treatment for you.  Keep up the positive attitude…we're all pulling for you!

                                                              Tricia

                                                              jag
                                                              Participant

                                                                Kevin, glad to hear that you are up to par on finding the best treatments.  ACT + IPI sounds like a great combo, hopefully it will be a knockout punch!

                                                                jag
                                                                Participant

                                                                  Kevin, glad to hear that you are up to par on finding the best treatments.  ACT + IPI sounds like a great combo, hopefully it will be a knockout punch!

                                                                  jag
                                                                  Participant

                                                                    Kevin, glad to hear that you are up to par on finding the best treatments.  ACT + IPI sounds like a great combo, hopefully it will be a knockout punch!

                                                                    ValinMtl
                                                                    Participant

                                                                      Dearest Kevin

                                                                      May this be the final 'ommppphhh' needed to push mel from your body.  Val xx (ipi/now ACT "Til")

                                                                      ValinMtl
                                                                      Participant

                                                                        Dearest Kevin

                                                                        May this be the final 'ommppphhh' needed to push mel from your body.  Val xx (ipi/now ACT "Til")

                                                                        ValinMtl
                                                                        Participant

                                                                          Dearest Kevin

                                                                          May this be the final 'ommppphhh' needed to push mel from your body.  Val xx (ipi/now ACT "Til")

                                                                          JerryfromFauq
                                                                          Participant

                                                                            Great to hear that you've got it going now.  COME ON IPI, kick ASS!

                                                                            JerryfromFauq
                                                                            Participant

                                                                              Great to hear that you've got it going now.  COME ON IPI, kick ASS!

                                                                              JerryfromFauq
                                                                              Participant

                                                                                Great to hear that you've got it going now.  COME ON IPI, kick ASS!

                                                                                zephyr66
                                                                                Participant

                                                                                  hi kevin… how are you doing?  pretty new to this site.  i'm in san diego also and partner has stage 4 as well.  hope you're tolerating the new drug well and look forward to new updates.

                                                                                   

                                                                                  sylvia

                                                                                    killmel
                                                                                    Participant

                                                                                      Hi Sylvia,

                                                                                      How is your partner doing on holistic therapy and zelboraf?? Is your treatment working?

                                                                                      I live in southern orange county & interested in holistic therapy. I would appreciate knowing what holistic treatment your partner is taking, as well as, where and or who is the doctor administering the holistic theraphy.

                                                                                       

                                                                                      Thanks so much for repying to my questions.

                                                                                       

                                                                                      Wishing you well with your treatment.

                                                                                       

                                                                                       

                                                                                      Mary

                                                                                       

                                                                                      zephyr66
                                                                                      Participant

                                                                                        mary… i don't see a profile for you or any way i can respond off the thread to answer your question.  whey you get a profile where i can respond, please let me know and i'll share.  thanks!

                                                                                         

                                                                                        sylvia

                                                                                        killmel
                                                                                        Participant

                                                                                          Hi Sylvia,

                                                                                          Thanks foryour reply.

                                                                                          I get so confused with computer & such, I could never figure out how to do my profile.

                                                                                          I would  very muh like to know about the holistic theraphy your partner is doing.

                                                                                          Please feel free to email me at this email [email protected]

                                                                                          Thanks,

                                                                                          Mary (my nickname is wendy)

                                                                                          killmel
                                                                                          Participant

                                                                                            Hi Sylvia,

                                                                                            Thanks foryour reply.

                                                                                            I get so confused with computer & such, I could never figure out how to do my profile.

                                                                                            I would  very muh like to know about the holistic theraphy your partner is doing.

                                                                                            Please feel free to email me at this email [email protected]

                                                                                            Thanks,

                                                                                            Mary (my nickname is wendy)

                                                                                            killmel
                                                                                            Participant

                                                                                              Hi Sylvia,

                                                                                              Thanks foryour reply.

                                                                                              I get so confused with computer & such, I could never figure out how to do my profile.

                                                                                              I would  very muh like to know about the holistic theraphy your partner is doing.

                                                                                              Please feel free to email me at this email [email protected]

                                                                                              Thanks,

                                                                                              Mary (my nickname is wendy)

                                                                                              zephyr66
                                                                                              Participant

                                                                                                mary… i don't see a profile for you or any way i can respond off the thread to answer your question.  whey you get a profile where i can respond, please let me know and i'll share.  thanks!

                                                                                                 

                                                                                                sylvia

                                                                                                zephyr66
                                                                                                Participant

                                                                                                  mary… i don't see a profile for you or any way i can respond off the thread to answer your question.  whey you get a profile where i can respond, please let me know and i'll share.  thanks!

                                                                                                   

                                                                                                  sylvia

                                                                                                  killmel
                                                                                                  Participant

                                                                                                    Hi Sylvia,

                                                                                                    How is your partner doing on holistic therapy and zelboraf?? Is your treatment working?

                                                                                                    I live in southern orange county & interested in holistic therapy. I would appreciate knowing what holistic treatment your partner is taking, as well as, where and or who is the doctor administering the holistic theraphy.

                                                                                                     

                                                                                                    Thanks so much for repying to my questions.

                                                                                                     

                                                                                                    Wishing you well with your treatment.

                                                                                                     

                                                                                                     

                                                                                                    Mary

                                                                                                     

                                                                                                    killmel
                                                                                                    Participant

                                                                                                      Hi Sylvia,

                                                                                                      How is your partner doing on holistic therapy and zelboraf?? Is your treatment working?

                                                                                                      I live in southern orange county & interested in holistic therapy. I would appreciate knowing what holistic treatment your partner is taking, as well as, where and or who is the doctor administering the holistic theraphy.

                                                                                                       

                                                                                                      Thanks so much for repying to my questions.

                                                                                                       

                                                                                                      Wishing you well with your treatment.

                                                                                                       

                                                                                                       

                                                                                                      Mary

                                                                                                       

                                                                                                    zephyr66
                                                                                                    Participant

                                                                                                      hi kevin… how are you doing?  pretty new to this site.  i'm in san diego also and partner has stage 4 as well.  hope you're tolerating the new drug well and look forward to new updates.

                                                                                                       

                                                                                                      sylvia

                                                                                                      zephyr66
                                                                                                      Participant

                                                                                                        hi kevin… how are you doing?  pretty new to this site.  i'm in san diego also and partner has stage 4 as well.  hope you're tolerating the new drug well and look forward to new updates.

                                                                                                         

                                                                                                        sylvia

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