› Forums › General Melanoma Community › First dose of Ipi… Yervoy.
- This topic has 48 replies, 13 voices, and was last updated 12 years, 4 months ago by
killmel.
- Post
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- October 19, 2011 at 4:55 am
Hey everyone.
There's not too much to update on, but it is another milestone in the journey, so I figured I'd let it be known for readers who still follow my posts. I just did my first dose of Ipilimumab/Yervoy. Although it's only been 5 hours, so far so good, hopefully any side effects will be minimal and I'll continue on with my future doses. And if I'm lucky it'll turn out all my cells from the ACT needed was one the last little *oomph* to clear these things out. Gosh that would be nice… We'll see, I'll keep you updated as I'm updated.Hey everyone.
There's not too much to update on, but it is another milestone in the journey, so I figured I'd let it be known for readers who still follow my posts. I just did my first dose of Ipilimumab/Yervoy. Although it's only been 5 hours, so far so good, hopefully any side effects will be minimal and I'll continue on with my future doses. And if I'm lucky it'll turn out all my cells from the ACT needed was one the last little *oomph* to clear these things out. Gosh that would be nice… We'll see, I'll keep you updated as I'm updated.Thanks for the continuing concern and support.
I'll talk to you soon.
-Kevin
- Replies
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- October 19, 2011 at 9:21 am
Kevin, I am stage 3 mel. I am 1 week past 2nd infusion of ipi. side effects have been minimal so far. Some people say thats great. Some say that its better to have controlled side effects bec. that means that the immune syst. is revving up. Who really knows. Everyone is different. Some say that the side effects dont always hit until more wks have past. anyway, good luck.
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- October 19, 2011 at 9:21 am
Kevin, I am stage 3 mel. I am 1 week past 2nd infusion of ipi. side effects have been minimal so far. Some people say thats great. Some say that its better to have controlled side effects bec. that means that the immune syst. is revving up. Who really knows. Everyone is different. Some say that the side effects dont always hit until more wks have past. anyway, good luck.
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- October 19, 2011 at 9:21 am
Kevin, I am stage 3 mel. I am 1 week past 2nd infusion of ipi. side effects have been minimal so far. Some people say thats great. Some say that its better to have controlled side effects bec. that means that the immune syst. is revving up. Who really knows. Everyone is different. Some say that the side effects dont always hit until more wks have past. anyway, good luck.
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- October 19, 2011 at 9:45 am
Thanks for the update, Kevin. Hopefully Yervoy will give your immune system whatever it needs to have a complete response. As you have recently completed adoptive cell therapy (ACT), I feel that it should work well.
Take care
Frank from Australia
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- October 19, 2011 at 9:45 am
Thanks for the update, Kevin. Hopefully Yervoy will give your immune system whatever it needs to have a complete response. As you have recently completed adoptive cell therapy (ACT), I feel that it should work well.
Take care
Frank from Australia
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- October 19, 2011 at 9:45 am
Thanks for the update, Kevin. Hopefully Yervoy will give your immune system whatever it needs to have a complete response. As you have recently completed adoptive cell therapy (ACT), I feel that it should work well.
Take care
Frank from Australia
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- October 19, 2011 at 10:15 am
Kevin,
Make sure your Oncologist is taking blood for (ALC) Absolute Lymphocyte count. If it doubles by week 7, most likely you will be a responder.
I wish you all the best
Jimmy B
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- October 19, 2011 at 10:53 am
Hi Kevin,
Of course we wait to see your posts and hear how you are doing!! You are a strong fighter and I look for your posts always. Keep those posts coming. Glad that so far so good with side effects. My Fingers crossed and strong prayers coming your way that this is what your body needed to help you kick that melanomat!! Let us know.
laurie from maine
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- October 19, 2011 at 10:53 am
Hi Kevin,
Of course we wait to see your posts and hear how you are doing!! You are a strong fighter and I look for your posts always. Keep those posts coming. Glad that so far so good with side effects. My Fingers crossed and strong prayers coming your way that this is what your body needed to help you kick that melanomat!! Let us know.
laurie from maine
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- October 19, 2011 at 10:53 am
Hi Kevin,
Of course we wait to see your posts and hear how you are doing!! You are a strong fighter and I look for your posts always. Keep those posts coming. Glad that so far so good with side effects. My Fingers crossed and strong prayers coming your way that this is what your body needed to help you kick that melanomat!! Let us know.
laurie from maine
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- October 19, 2011 at 10:15 am
Kevin,
Make sure your Oncologist is taking blood for (ALC) Absolute Lymphocyte count. If it doubles by week 7, most likely you will be a responder.
I wish you all the best
Jimmy B
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- October 19, 2011 at 10:15 am
Kevin,
Make sure your Oncologist is taking blood for (ALC) Absolute Lymphocyte count. If it doubles by week 7, most likely you will be a responder.
I wish you all the best
Jimmy B
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- October 19, 2011 at 12:05 pm
Hi Kevin
I´m so glad that you´re on Ipilimumab now. It could be your magic bullet. The (short) story of my wife, which I posted on June 24, three days after we got the results of 4 doses of Ipilimumab (3 mg pr.kg). She is now 4 months NED, a sensationel comeback in our fight against cancer! 🙂 Good luck to you my friend.
Hi everyone
I´ve been reading posts at this Bulletin Board for almost a year now. Some posts I have read with tears in my eyes, and some with joy. Here is our story (short version):
I am the husband to a 39 year old woman from Denmark in Europe.
In 2003 she had a mole removed from her thigh (Stage II). It contained melanoma-cells.
In 2007 melanoma had spread to a lymph-node in her groin (Stage III). Surgery was needed.
In 2008 melanoma relapsed in another lymph-node, surgery again.
In 2009 melanoma hit us hard (Stage IV). It had spread to her lungs, one met in each lung. The size of the mets was 25 mm and 16 mm respectively. Surgery was fortunately possible.
In October 2010 melanoma went back. This time there was multiples mets in each lung. About 5-6 mets in each lung. The biggest was 19 mm. It was unsurgeable, which was very hard to cope with.
In November she began Interferon/Interleukin-2 treatment. It was tough beyond imagination. She had all the known sideeffects, and she was so bad during hospitalization. The midway PET/CT scans in January revealed that she was a responder! Scans showed that all the mets had become inactive or necrotic. Some mets had even shrunk a little bit. We were delighted, and she continued with the third and fourth series of Interferon/IL-2.
February 15 we got the results of the next scan. We were optimistic because the midway scans was indeed promising. We were shocked when told that the melanoma had began to grow again. There was 2 active mets now. One big met, about 32 mm in diameter, in her right lung lightened up. In addiction there was a lot of fluid in the right lung membrane, and it probably contained melanoma-cells. All other mets was still inactive, except one, and our doctor feared that it would be only a matter of time, before the other mets would begin to grow again. We were devastated.
Our doctor suggested Ipilimumab, and my wife started March 11, on the same day Japan was shaken by the huge earthquake. I watched it on TV while she was receiving the first dose of ipilimumab (3 mg/kg dose). I remember wishing that the drug was the earthquake of our lives…
My wife have always been a positive and happy human being, no matter what challenges life would bring, she still truly believe that she could defeat this Melanoma Devil. She began consulting a Chinese doctor and received acupuncture twice a week. Beside this she trained 4-5 times a week, fitness and running. In these situations we talked about preparing your body to fight the cancer, with a "little" help from our friend, ipilimumab…
She received 4 doses every third week and got a CT scan in June.
Three days ago on June 21 we arrived to the hospital to talk with our doctor about the results of the CT scan. The time from the scans being done and to get the results is awful with a lot of anxiety, you guys all know… The scan showed that the 32 mm met in the right lung was completely GONE!!!!! The fluid was gone too, and the x-ray showed a nice healthy looking right lung. We were stunned. I hugged my wife with a lot of tears in my eyes. Our doctor was very delighted too. Ipilimumab had worked much better than expected. We had hoped for stabilization, maybe shrinkage, if we were lucky. But this???? Unbelievable. Some other small mets was still there but hasn´t grown in size in half a year, and our doctor said it very well could be necrotic tissue.
This is where we stand now. We´re thrilled and delighted and so so happy. We have now dared to plan for more than a month 🙂
So this story is to all you Warriors out there, keep on fighting with believe and trust in your hearts. The path is very tough but the battle can be won, sooner or later. We´ll keep fighting this Devil.
Kind regards
willtolive
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- October 19, 2011 at 12:05 pm
Hi Kevin
I´m so glad that you´re on Ipilimumab now. It could be your magic bullet. The (short) story of my wife, which I posted on June 24, three days after we got the results of 4 doses of Ipilimumab (3 mg pr.kg). She is now 4 months NED, a sensationel comeback in our fight against cancer! 🙂 Good luck to you my friend.
Hi everyone
I´ve been reading posts at this Bulletin Board for almost a year now. Some posts I have read with tears in my eyes, and some with joy. Here is our story (short version):
I am the husband to a 39 year old woman from Denmark in Europe.
In 2003 she had a mole removed from her thigh (Stage II). It contained melanoma-cells.
In 2007 melanoma had spread to a lymph-node in her groin (Stage III). Surgery was needed.
In 2008 melanoma relapsed in another lymph-node, surgery again.
In 2009 melanoma hit us hard (Stage IV). It had spread to her lungs, one met in each lung. The size of the mets was 25 mm and 16 mm respectively. Surgery was fortunately possible.
In October 2010 melanoma went back. This time there was multiples mets in each lung. About 5-6 mets in each lung. The biggest was 19 mm. It was unsurgeable, which was very hard to cope with.
In November she began Interferon/Interleukin-2 treatment. It was tough beyond imagination. She had all the known sideeffects, and she was so bad during hospitalization. The midway PET/CT scans in January revealed that she was a responder! Scans showed that all the mets had become inactive or necrotic. Some mets had even shrunk a little bit. We were delighted, and she continued with the third and fourth series of Interferon/IL-2.
February 15 we got the results of the next scan. We were optimistic because the midway scans was indeed promising. We were shocked when told that the melanoma had began to grow again. There was 2 active mets now. One big met, about 32 mm in diameter, in her right lung lightened up. In addiction there was a lot of fluid in the right lung membrane, and it probably contained melanoma-cells. All other mets was still inactive, except one, and our doctor feared that it would be only a matter of time, before the other mets would begin to grow again. We were devastated.
Our doctor suggested Ipilimumab, and my wife started March 11, on the same day Japan was shaken by the huge earthquake. I watched it on TV while she was receiving the first dose of ipilimumab (3 mg/kg dose). I remember wishing that the drug was the earthquake of our lives…
My wife have always been a positive and happy human being, no matter what challenges life would bring, she still truly believe that she could defeat this Melanoma Devil. She began consulting a Chinese doctor and received acupuncture twice a week. Beside this she trained 4-5 times a week, fitness and running. In these situations we talked about preparing your body to fight the cancer, with a "little" help from our friend, ipilimumab…
She received 4 doses every third week and got a CT scan in June.
Three days ago on June 21 we arrived to the hospital to talk with our doctor about the results of the CT scan. The time from the scans being done and to get the results is awful with a lot of anxiety, you guys all know… The scan showed that the 32 mm met in the right lung was completely GONE!!!!! The fluid was gone too, and the x-ray showed a nice healthy looking right lung. We were stunned. I hugged my wife with a lot of tears in my eyes. Our doctor was very delighted too. Ipilimumab had worked much better than expected. We had hoped for stabilization, maybe shrinkage, if we were lucky. But this???? Unbelievable. Some other small mets was still there but hasn´t grown in size in half a year, and our doctor said it very well could be necrotic tissue.
This is where we stand now. We´re thrilled and delighted and so so happy. We have now dared to plan for more than a month 🙂
So this story is to all you Warriors out there, keep on fighting with believe and trust in your hearts. The path is very tough but the battle can be won, sooner or later. We´ll keep fighting this Devil.
Kind regards
willtolive
-
- October 19, 2011 at 12:05 pm
Hi Kevin
I´m so glad that you´re on Ipilimumab now. It could be your magic bullet. The (short) story of my wife, which I posted on June 24, three days after we got the results of 4 doses of Ipilimumab (3 mg pr.kg). She is now 4 months NED, a sensationel comeback in our fight against cancer! 🙂 Good luck to you my friend.
Hi everyone
I´ve been reading posts at this Bulletin Board for almost a year now. Some posts I have read with tears in my eyes, and some with joy. Here is our story (short version):
I am the husband to a 39 year old woman from Denmark in Europe.
In 2003 she had a mole removed from her thigh (Stage II). It contained melanoma-cells.
In 2007 melanoma had spread to a lymph-node in her groin (Stage III). Surgery was needed.
In 2008 melanoma relapsed in another lymph-node, surgery again.
In 2009 melanoma hit us hard (Stage IV). It had spread to her lungs, one met in each lung. The size of the mets was 25 mm and 16 mm respectively. Surgery was fortunately possible.
In October 2010 melanoma went back. This time there was multiples mets in each lung. About 5-6 mets in each lung. The biggest was 19 mm. It was unsurgeable, which was very hard to cope with.
In November she began Interferon/Interleukin-2 treatment. It was tough beyond imagination. She had all the known sideeffects, and she was so bad during hospitalization. The midway PET/CT scans in January revealed that she was a responder! Scans showed that all the mets had become inactive or necrotic. Some mets had even shrunk a little bit. We were delighted, and she continued with the third and fourth series of Interferon/IL-2.
February 15 we got the results of the next scan. We were optimistic because the midway scans was indeed promising. We were shocked when told that the melanoma had began to grow again. There was 2 active mets now. One big met, about 32 mm in diameter, in her right lung lightened up. In addiction there was a lot of fluid in the right lung membrane, and it probably contained melanoma-cells. All other mets was still inactive, except one, and our doctor feared that it would be only a matter of time, before the other mets would begin to grow again. We were devastated.
Our doctor suggested Ipilimumab, and my wife started March 11, on the same day Japan was shaken by the huge earthquake. I watched it on TV while she was receiving the first dose of ipilimumab (3 mg/kg dose). I remember wishing that the drug was the earthquake of our lives…
My wife have always been a positive and happy human being, no matter what challenges life would bring, she still truly believe that she could defeat this Melanoma Devil. She began consulting a Chinese doctor and received acupuncture twice a week. Beside this she trained 4-5 times a week, fitness and running. In these situations we talked about preparing your body to fight the cancer, with a "little" help from our friend, ipilimumab…
She received 4 doses every third week and got a CT scan in June.
Three days ago on June 21 we arrived to the hospital to talk with our doctor about the results of the CT scan. The time from the scans being done and to get the results is awful with a lot of anxiety, you guys all know… The scan showed that the 32 mm met in the right lung was completely GONE!!!!! The fluid was gone too, and the x-ray showed a nice healthy looking right lung. We were stunned. I hugged my wife with a lot of tears in my eyes. Our doctor was very delighted too. Ipilimumab had worked much better than expected. We had hoped for stabilization, maybe shrinkage, if we were lucky. But this???? Unbelievable. Some other small mets was still there but hasn´t grown in size in half a year, and our doctor said it very well could be necrotic tissue.
This is where we stand now. We´re thrilled and delighted and so so happy. We have now dared to plan for more than a month 🙂
So this story is to all you Warriors out there, keep on fighting with believe and trust in your hearts. The path is very tough but the battle can be won, sooner or later. We´ll keep fighting this Devil.
Kind regards
willtolive
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- October 20, 2011 at 6:54 am
Great to hear that you've got it going now. COME ON IPI, kick ASS!
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- October 20, 2011 at 6:54 am
Great to hear that you've got it going now. COME ON IPI, kick ASS!
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- October 20, 2011 at 6:54 am
Great to hear that you've got it going now. COME ON IPI, kick ASS!
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- December 10, 2011 at 3:57 pm
hi kevin… how are you doing? pretty new to this site. i'm in san diego also and partner has stage 4 as well. hope you're tolerating the new drug well and look forward to new updates.
sylvia
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- December 10, 2011 at 5:01 pm
Hi Sylvia,
How is your partner doing on holistic therapy and zelboraf?? Is your treatment working?
I live in southern orange county & interested in holistic therapy. I would appreciate knowing what holistic treatment your partner is taking, as well as, where and or who is the doctor administering the holistic theraphy.
Thanks so much for repying to my questions.
Wishing you well with your treatment.
Mary
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- December 11, 2011 at 12:48 am
Hi Sylvia,
Thanks foryour reply.
I get so confused with computer & such, I could never figure out how to do my profile.
I would very muh like to know about the holistic theraphy your partner is doing.
Please feel free to email me at this email [email protected]
Thanks,
Mary (my nickname is wendy)
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- December 11, 2011 at 12:48 am
Hi Sylvia,
Thanks foryour reply.
I get so confused with computer & such, I could never figure out how to do my profile.
I would very muh like to know about the holistic theraphy your partner is doing.
Please feel free to email me at this email [email protected]
Thanks,
Mary (my nickname is wendy)
-
- December 11, 2011 at 12:48 am
Hi Sylvia,
Thanks foryour reply.
I get so confused with computer & such, I could never figure out how to do my profile.
I would very muh like to know about the holistic theraphy your partner is doing.
Please feel free to email me at this email [email protected]
Thanks,
Mary (my nickname is wendy)
-
- December 10, 2011 at 5:01 pm
Hi Sylvia,
How is your partner doing on holistic therapy and zelboraf?? Is your treatment working?
I live in southern orange county & interested in holistic therapy. I would appreciate knowing what holistic treatment your partner is taking, as well as, where and or who is the doctor administering the holistic theraphy.
Thanks so much for repying to my questions.
Wishing you well with your treatment.
Mary
-
- December 10, 2011 at 5:01 pm
Hi Sylvia,
How is your partner doing on holistic therapy and zelboraf?? Is your treatment working?
I live in southern orange county & interested in holistic therapy. I would appreciate knowing what holistic treatment your partner is taking, as well as, where and or who is the doctor administering the holistic theraphy.
Thanks so much for repying to my questions.
Wishing you well with your treatment.
Mary
-
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