Experience with Liver Mets
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Experience with Liver Mets

› Forums › General Melanoma Community › Experience with Liver Mets

  • Post
    • December 22, 2015 at 3:20 am
    Squash
    Participant

    I have liver mets and am on Keytruda for five months now.

    My blood work for liver and LDH etc is normal but just lately i have noticed my liver is tender in the mornings and i can sort of feel activity going on there. Sometimes i feel a sharp twinge as well.

    Is this consistent with worsening liver disease? What can i expect if things get worse?

    Are their any treatment possibilites. I am due for a PET scan next month but already feel like things are spiralling out of control.

     

     

     

     

Viewing 2 reply threads
  • Replies
      • December 22, 2015 at 5:23 pm
      Mat
      Participant

      I've had 10+ liver mets since my Stage IV diagnosis in 2013.  Before treatment, my LDH was elevated (600+ on whatever scale my doctor uses), my other liver marker were off, I had drenching night sweats and noticeable liver tenderness–which was fairly constant and was aggravated by lifting and pulling, or moving around in bed.  I couldn't comfortably sleep on my stomach, etc.  Since starting treatment, my liver mets have been under control.  My LDH has only been slightly elevated, other liver markers normal and limited episodes of night sweats.  I will occassionally have liver sensation (and/or night sweats) and wonder whether this represents a reawakening of my liver tumors (which shrunk, but have not disappered).  To date, my wonder notwithstanding, this has not been an issue.  I would continue to be watchful and vigilant and move up your scan if you sense a persistent problem.  Otherwise, I would wait it out.  Presumably you'll have labs again with your Keytruda infusion where they'll check liver function.

      • December 22, 2015 at 5:23 pm
      Mat
      Participant

      I've had 10+ liver mets since my Stage IV diagnosis in 2013.  Before treatment, my LDH was elevated (600+ on whatever scale my doctor uses), my other liver marker were off, I had drenching night sweats and noticeable liver tenderness–which was fairly constant and was aggravated by lifting and pulling, or moving around in bed.  I couldn't comfortably sleep on my stomach, etc.  Since starting treatment, my liver mets have been under control.  My LDH has only been slightly elevated, other liver markers normal and limited episodes of night sweats.  I will occassionally have liver sensation (and/or night sweats) and wonder whether this represents a reawakening of my liver tumors (which shrunk, but have not disappered).  To date, my wonder notwithstanding, this has not been an issue.  I would continue to be watchful and vigilant and move up your scan if you sense a persistent problem.  Otherwise, I would wait it out.  Presumably you'll have labs again with your Keytruda infusion where they'll check liver function.

      • December 22, 2015 at 5:23 pm
      Mat
      Participant

      I've had 10+ liver mets since my Stage IV diagnosis in 2013.  Before treatment, my LDH was elevated (600+ on whatever scale my doctor uses), my other liver marker were off, I had drenching night sweats and noticeable liver tenderness–which was fairly constant and was aggravated by lifting and pulling, or moving around in bed.  I couldn't comfortably sleep on my stomach, etc.  Since starting treatment, my liver mets have been under control.  My LDH has only been slightly elevated, other liver markers normal and limited episodes of night sweats.  I will occassionally have liver sensation (and/or night sweats) and wonder whether this represents a reawakening of my liver tumors (which shrunk, but have not disappered).  To date, my wonder notwithstanding, this has not been an issue.  I would continue to be watchful and vigilant and move up your scan if you sense a persistent problem.  Otherwise, I would wait it out.  Presumably you'll have labs again with your Keytruda infusion where they'll check liver function.

        • December 22, 2015 at 8:54 pm
        Scooby123
        Participant

        Hi there, I have liver mets too , I have had ippi treatment which shrunk my tumours by 50% but I have experienced when lifting bags of shopping ect pain as if I have pulled my side. What size was they and what are they now. Hopefully your next scan will be improving . Mine are still the same from last scan.

        scooby

        • December 22, 2015 at 8:54 pm
        Scooby123
        Participant

        Hi there, I have liver mets too , I have had ippi treatment which shrunk my tumours by 50% but I have experienced when lifting bags of shopping ect pain as if I have pulled my side. What size was they and what are they now. Hopefully your next scan will be improving . Mine are still the same from last scan.

        scooby

        • December 22, 2015 at 8:54 pm
        Scooby123
        Participant

        Hi there, I have liver mets too , I have had ippi treatment which shrunk my tumours by 50% but I have experienced when lifting bags of shopping ect pain as if I have pulled my side. What size was they and what are they now. Hopefully your next scan will be improving . Mine are still the same from last scan.

        scooby

        • December 23, 2015 at 2:39 am
        Squash
        Participant

        They were under 1cm originally about five months ago but who knows now. I am due for a scan at the end of Jan.

        My doc says as long as the the blood work looks good no point rushing the scans. He wants me to do 6 to 8 infusins before he scans.

        Since i had hep B when i was young i think my liver is not in great shape.

         

        • December 23, 2015 at 2:39 am
        Squash
        Participant

        They were under 1cm originally about five months ago but who knows now. I am due for a scan at the end of Jan.

        My doc says as long as the the blood work looks good no point rushing the scans. He wants me to do 6 to 8 infusins before he scans.

        Since i had hep B when i was young i think my liver is not in great shape.

         

        • December 23, 2015 at 2:39 am
        Squash
        Participant

        They were under 1cm originally about five months ago but who knows now. I am due for a scan at the end of Jan.

        My doc says as long as the the blood work looks good no point rushing the scans. He wants me to do 6 to 8 infusins before he scans.

        Since i had hep B when i was young i think my liver is not in great shape.

         

        • January 6, 2016 at 11:37 pm
        Squash
        Participant

        My right side has the pain exactly as you describe. It feels like i pulled a muscle there.

        Also when i am driving the car my right side feels uncomfortable.

        I saw the dco yesterday and he said all my blood work is still good LDH normal, liver function normal etc so he wants me to do the sixth keytruda infusion this week before he scans in a couple of weeks.

        That will make it almost six months since my last scan.

        I am considering changing docs after this as he just seems to laid back and not listening to me.

         

         

         

        • January 6, 2016 at 11:37 pm
        Squash
        Participant

        My right side has the pain exactly as you describe. It feels like i pulled a muscle there.

        Also when i am driving the car my right side feels uncomfortable.

        I saw the dco yesterday and he said all my blood work is still good LDH normal, liver function normal etc so he wants me to do the sixth keytruda infusion this week before he scans in a couple of weeks.

        That will make it almost six months since my last scan.

        I am considering changing docs after this as he just seems to laid back and not listening to me.

         

         

         

        • January 6, 2016 at 11:37 pm
        Squash
        Participant

        My right side has the pain exactly as you describe. It feels like i pulled a muscle there.

        Also when i am driving the car my right side feels uncomfortable.

        I saw the dco yesterday and he said all my blood work is still good LDH normal, liver function normal etc so he wants me to do the sixth keytruda infusion this week before he scans in a couple of weeks.

        That will make it almost six months since my last scan.

        I am considering changing docs after this as he just seems to laid back and not listening to me.

         

         

         

        • December 23, 2015 at 2:34 am
        Squash
        Participant

        I had labs two weeks before my last infusion and they were all normal for liver function and LDH.

        Urea was just over the limit by .01

        My liver function has always been normal but I never felt the twinges that i feel now.

        It is especially more noticeable in the mornings.

        Wow you are lucky that the meds have worked for you thank god.

        It sounds like your liver was really playing up big time. I have never had any symptoms like you descri be. I sound like a wooz.in comparison.

        Thanks for your input it is much appreciated.

         

         

         

        • December 23, 2015 at 2:34 am
        Squash
        Participant

        I had labs two weeks before my last infusion and they were all normal for liver function and LDH.

        Urea was just over the limit by .01

        My liver function has always been normal but I never felt the twinges that i feel now.

        It is especially more noticeable in the mornings.

        Wow you are lucky that the meds have worked for you thank god.

        It sounds like your liver was really playing up big time. I have never had any symptoms like you descri be. I sound like a wooz.in comparison.

        Thanks for your input it is much appreciated.

         

         

         

        • December 23, 2015 at 2:34 am
        Squash
        Participant

        I had labs two weeks before my last infusion and they were all normal for liver function and LDH.

        Urea was just over the limit by .01

        My liver function has always been normal but I never felt the twinges that i feel now.

        It is especially more noticeable in the mornings.

        Wow you are lucky that the meds have worked for you thank god.

        It sounds like your liver was really playing up big time. I have never had any symptoms like you descri be. I sound like a wooz.in comparison.

        Thanks for your input it is much appreciated.

         

         

         

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