Yervoy crushed the brain mets!
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Yervoy crushed the brain mets!

› Forums › General Melanoma Community › Yervoy crushed the brain mets!

  • Post
    • July 27, 2011 at 12:25 am
    MaryBeth and Jeff
    Participant

    What an emotional day today. Some of you may have read my previous post where my husbands medical oncologist felt he was a Yervoy non-responder……Well… we met with the Neurosurgeon today to go over the findings of yesterday's MRI. Of the 19 brain lesions most are gone and the remaining few are barely visible!!  The neurosurgeon was amazed to say the least.

    What an emotional day today. Some of you may have read my previous post where my husbands medical oncologist felt he was a Yervoy non-responder……Well… we met with the Neurosurgeon today to go over the findings of yesterday's MRI. Of the 19 brain lesions most are gone and the remaining few are barely visible!!  The neurosurgeon was amazed to say the least. He said he actually expected to see many more new lesions as he felt the brain mets were very aggressive (an increase from 5 lesions to 19 total in 2 1/2 weeks)  and he has never seen 19 lesions respond like that. He attributes this to the Yervoy! (per neuro he hasnt seen Gamma produce such amazing results on so many lesions)Granted my husband is still fighting the ever increasing tumors, nodules and sub q's on his neck, back, legs, arms etc. which seem to have appeared rather rapidly after his 3rd Yervoy treatment. (He finished his 4th and final Yervoy treatment on July 15th). His neuro does not feel these are immune responses…but hey, let him stick to his gamma knife expertise…because the medical onc was mistaken in determining my husband was a Yervoy non responder. I give all the Glory to God and continue to pray for all of the fellow warriors who are fighting this insidious disease. 

Viewing 13 reply threads
  • Replies
      • July 27, 2011 at 2:43 am
      BethA in VA
      Participant

      I'm happy to hear he has responded and shows improvement.  Those are really nice results to get.  Sounds like he is a winner!!  Good luck in the rest of the fight!  Beth 3/B

      • July 27, 2011 at 2:43 am
      BethA in VA
      Participant

      I'm happy to hear he has responded and shows improvement.  Those are really nice results to get.  Sounds like he is a winner!!  Good luck in the rest of the fight!  Beth 3/B

      • July 27, 2011 at 4:01 am
      cfw9186
      Participant

      Miracles happen everyday and we hear, praise the Lord to hear them, God bless you and rest in arms of our Lord.

      • July 27, 2011 at 4:01 am
      cfw9186
      Participant

      Miracles happen everyday and we hear, praise the Lord to hear them, God bless you and rest in arms of our Lord.

      • July 27, 2011 at 11:40 am
      FormerCaregiver
      Participant

      Congratulations on the great scan results! I feel that scans are the only sure way to tell
      how well any melanoma treatment is working. It must be a relief to find that Yervoy is
      actually working very well indeed!

      You remain in my thoughts and prayers.

      Frank from Australia

        • July 27, 2011 at 12:59 pm
        Vermont_Donna
        Participant

        Hi,

        I am a complete respondwr to Ipi (yervoy)…but I didnt have brain mets. In the clinical trial I was in from December 2010 to February 2011, in that 12 weeks of active treatment, my oncologist explained that new sub q's and cutaneous lesions were 'acceptable" in the trial, meaning I wouldnt be kicked out of the clinical trial..and I did continue to have new melanomas develop….you would have to read my profile to see the exact history of my treatment with Yervoy as I dont remember the details of when the sub q's etc stopped developing. I did develop alot of inflammation at the site of most of my melanoma, and thI could see that and it was picked up on my scans 2 weeks after my 4th treatment. 12 weeks after that my scans were CLEAR!

        Best of luck with the yervoy continuing to do its magic!

        Vermont_Donna, stage 3a, NED

        • July 27, 2011 at 12:59 pm
        Vermont_Donna
        Participant

        Hi,

        I am a complete respondwr to Ipi (yervoy)…but I didnt have brain mets. In the clinical trial I was in from December 2010 to February 2011, in that 12 weeks of active treatment, my oncologist explained that new sub q's and cutaneous lesions were 'acceptable" in the trial, meaning I wouldnt be kicked out of the clinical trial..and I did continue to have new melanomas develop….you would have to read my profile to see the exact history of my treatment with Yervoy as I dont remember the details of when the sub q's etc stopped developing. I did develop alot of inflammation at the site of most of my melanoma, and thI could see that and it was picked up on my scans 2 weeks after my 4th treatment. 12 weeks after that my scans were CLEAR!

        Best of luck with the yervoy continuing to do its magic!

        Vermont_Donna, stage 3a, NED

      • July 27, 2011 at 11:40 am
      FormerCaregiver
      Participant

      Congratulations on the great scan results! I feel that scans are the only sure way to tell
      how well any melanoma treatment is working. It must be a relief to find that Yervoy is
      actually working very well indeed!

      You remain in my thoughts and prayers.

      Frank from Australia

      • July 27, 2011 at 1:00 pm
      MichaelFL
      Participant

      That is some kinda good news! Celebrate Christmas early!

      Keep it up!

      Michael

        • July 27, 2011 at 4:02 pm
        Manubuzzi
        Participant

        Really good news !!!! I Hope the worst has passed in your lifes! 

        Health and strength from Argentina!

        • July 27, 2011 at 4:02 pm
        Manubuzzi
        Participant

        Really good news !!!! I Hope the worst has passed in your lifes! 

        Health and strength from Argentina!

      • July 27, 2011 at 1:00 pm
      MichaelFL
      Participant

      That is some kinda good news! Celebrate Christmas early!

      Keep it up!

      Michael

      • July 27, 2011 at 4:07 pm
      Carol Taylor
      Participant

      Hallelujah moment indeed! May Jeff continue to experience blessings as he fights. He's got you, he's blessed to have you in his  corner.

      Lord, in Your mercy, thank You for the work being done and we pray for continued miracles for Jeff. Amen and Amen!

      Grace and peace,

      Carol

      • July 27, 2011 at 4:07 pm
      Carol Taylor
      Participant

      Hallelujah moment indeed! May Jeff continue to experience blessings as he fights. He's got you, he's blessed to have you in his  corner.

      Lord, in Your mercy, thank You for the work being done and we pray for continued miracles for Jeff. Amen and Amen!

      Grace and peace,

      Carol

      • July 27, 2011 at 5:36 pm
      kylez
      Participant

      Tha's fantastic news Mary Beth.

      Thx for sharing your husband's experiences/response to IPI w/ brain mets. That's really useful to hear for other patients on IPI w/brain mets. The timing info of the response so far (a week or two after the fourth treatment) is what I would have asked if you didn't include it.

      That's so, so awesome to get news of that kind of response.

      – Kyle

      • July 27, 2011 at 5:36 pm
      kylez
      Participant

      Tha's fantastic news Mary Beth.

      Thx for sharing your husband's experiences/response to IPI w/ brain mets. That's really useful to hear for other patients on IPI w/brain mets. The timing info of the response so far (a week or two after the fourth treatment) is what I would have asked if you didn't include it.

      That's so, so awesome to get news of that kind of response.

      – Kyle

        • July 27, 2011 at 9:42 pm
        NYKaren
        Participant

        Fantastic news!

        • July 27, 2011 at 9:42 pm
        NYKaren
        Participant

        Fantastic news!

      • July 29, 2011 at 6:15 pm
      cfw9186
      Participant

      Wonderful news on the brain mets, my sub'q's as we call them after the 4th ipi are beginning to go away, Praise the Lord, can't wait to see what my lung mets look like when I get scanned in August, but I feel there may be some good news on the horizon.  I am not doing brain rad, but only to keep ahead of the the mets, Lord Help us. …what a patch we must march.  People ask how do you do it, well, you place one foot in front of the other and then when you can't the Lord picks you up and you hold on tight………God bless you all and keep us all posted, as lab rats on the IPI trail, I do'n't care what the docs say……us in the fields must keep strong and compare notes.  Kitty

      • July 29, 2011 at 6:15 pm
      cfw9186
      Participant

      Wonderful news on the brain mets, my sub'q's as we call them after the 4th ipi are beginning to go away, Praise the Lord, can't wait to see what my lung mets look like when I get scanned in August, but I feel there may be some good news on the horizon.  I am not doing brain rad, but only to keep ahead of the the mets, Lord Help us. …what a patch we must march.  People ask how do you do it, well, you place one foot in front of the other and then when you can't the Lord picks you up and you hold on tight………God bless you all and keep us all posted, as lab rats on the IPI trail, I do'n't care what the docs say……us in the fields must keep strong and compare notes.  Kitty

        • July 29, 2011 at 6:17 pm
        cfw9186
        Participant

        Correction, I am doing brain rad right now to keep ahead of the tumors……..

        • July 29, 2011 at 6:17 pm
        cfw9186
        Participant

        Correction, I am doing brain rad right now to keep ahead of the tumors……..

        • July 30, 2011 at 8:41 pm
        mombase
        Participant

        Your news is so awesome and definitely gives me hope as well. I will be starting whole brain radiation shortly and then have chosen Yervoy as my line of offense for lung mets.  I am getting more and more hopeful as I read stories like yours! ~ Cristy

        • July 30, 2011 at 8:41 pm
        mombase
        Participant

        Your news is so awesome and definitely gives me hope as well. I will be starting whole brain radiation shortly and then have chosen Yervoy as my line of offense for lung mets.  I am getting more and more hopeful as I read stories like yours! ~ Cristy

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