Sue26

I am glad I searched for E7080 trial on this site! My husband commenced the BRAF/MEK trial 9 weeks ago and scans done this past Monday have revealed no shrinkage in tumour size but rapid increase. He was immediately taken off the trial and has been offered a place in E7080 but has to have a 30 day washout period prior to commencing, after ceasing the BRAF/MEK tablets (he had also been on the BRAF trial which initially helped with reduction in size of tumours and cessation of pain) the pain immediately escalated and pain relief has been increased. He will also have radiotherapy.  Again we will put all our postive thoughts into this new trial – glad to see ther have been many positive stories so far.

I am glad I searched for E7080 trial on this site! My husband commenced the BRAF/MEK trial 9 weeks ago and scans done this past Monday have revealed no shrinkage in tumour size but rapid increase. He was immediately taken off the trial and has been offered a place in E7080 but has to have a 30 day washout period prior to commencing, after ceasing the BRAF/MEK tablets (he had also been on the BRAF trial which initially helped with reduction in size of tumours and cessation of pain) the pain immediately escalated and pain relief has been increased. He will also have radiotherapy.  Again we will put all our postive thoughts into this new trial – glad to see ther have been many positive stories so far.

Greetings from Australia. My husband was diagnosed with Stage 4 MMM in late August 2010 and given an extremely poor prognosis. He was accepted into the GSK BRAF trial which had great results until Jan/Feb when 2 out 5 of his tumours started to increase in size after initally shrinking. He was then commenced on the combo BRAF/MEK trial which he started about 6 weeks ago. Not sure how this trial is going, after having no side affects at all at the commencement  he has lately been feeling very unwell – extreme fatigue (which may be from the pain relief drugs), nausea and pain. He needs pain relief at all times. He is not due for CT scans for another couple of weeks – this will be the thing that tells us whats going on. Fingers crossed for good results.

Greetings from Australia. My husband was diagnosed with Stage 4 MMM in late August 2010 and given an extremely poor prognosis. He was accepted into the GSK BRAF trial which had great results until Jan/Feb when 2 out 5 of his tumours started to increase in size after initally shrinking. He was then commenced on the combo BRAF/MEK trial which he started about 6 weeks ago. Not sure how this trial is going, after having no side affects at all at the commencement  he has lately been feeling very unwell – extreme fatigue (which may be from the pain relief drugs), nausea and pain. He needs pain relief at all times. He is not due for CT scans for another couple of weeks – this will be the thing that tells us whats going on. Fingers crossed for good results.