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paul

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      paul
      Participant

        Looking forward: did you try dose reduction? With Zelboraf I had ten days off, then a dose reduction, and a slightly reduced dose, and found the problems mostly resolved.

        All the best–

        Paul

         

         

        paul
        Participant

          Looking forward: did you try dose reduction? With Zelboraf I had ten days off, then a dose reduction, and a slightly reduced dose, and found the problems mostly resolved.

          All the best–

          Paul

           

           

          paul
          Participant

            Looking forward: did you try dose reduction? With Zelboraf I had ten days off, then a dose reduction, and a slightly reduced dose, and found the problems mostly resolved.

            All the best–

            Paul

             

             

            paul
            Participant

              Hi Dave,

              I have been on MEK combo for more than a year and a half now, and seem to be doing well on it. I work full time. From what I've read, including personal accounts on this site, responses differ greatly; for some, it seems to work for several years. Wishing you a good result with it–

              Paul

              paul
              Participant

                Hi Dave,

                I have been on MEK combo for more than a year and a half now, and seem to be doing well on it. I work full time. From what I've read, including personal accounts on this site, responses differ greatly; for some, it seems to work for several years. Wishing you a good result with it–

                Paul

                paul
                Participant

                  Hi Dave,

                  I have been on MEK combo for more than a year and a half now, and seem to be doing well on it. I work full time. From what I've read, including personal accounts on this site, responses differ greatly; for some, it seems to work for several years. Wishing you a good result with it–

                  Paul

                  paul
                  Participant

                    Hello.

                    I have been on Mek combo over a year and a half, working the whole time, and get chills/fevers occasionally. My own experience, and what others have reported, is that these come less frequently over time. When the chills hit now, I go home, throw on a few extra blankets, drink a lot of water, and take tylenol (which does help a lot). You should talk to your oncologist about whether a day or two off if/when you have bad fevers (102+) is part of his/her protocol. The one time I went to the hospital to see if I had an infection causing the fever, they just gave me a few bags of fluids. I do think hydration while on the drug is important, and sometimes drink sports drinks when I feel something coming on. For me, a day or two off the MEDs, taking tylenol, usually brings the fever down–but you should check with your doctor about this.

                    Good luck with it–

                    Paul

                    paul
                    Participant

                      Hello.

                      I have been on Mek combo over a year and a half, working the whole time, and get chills/fevers occasionally. My own experience, and what others have reported, is that these come less frequently over time. When the chills hit now, I go home, throw on a few extra blankets, drink a lot of water, and take tylenol (which does help a lot). You should talk to your oncologist about whether a day or two off if/when you have bad fevers (102+) is part of his/her protocol. The one time I went to the hospital to see if I had an infection causing the fever, they just gave me a few bags of fluids. I do think hydration while on the drug is important, and sometimes drink sports drinks when I feel something coming on. For me, a day or two off the MEDs, taking tylenol, usually brings the fever down–but you should check with your doctor about this.

                      Good luck with it–

                      Paul

                      paul
                      Participant

                        Hello.

                        I have been on Mek combo over a year and a half, working the whole time, and get chills/fevers occasionally. My own experience, and what others have reported, is that these come less frequently over time. When the chills hit now, I go home, throw on a few extra blankets, drink a lot of water, and take tylenol (which does help a lot). You should talk to your oncologist about whether a day or two off if/when you have bad fevers (102+) is part of his/her protocol. The one time I went to the hospital to see if I had an infection causing the fever, they just gave me a few bags of fluids. I do think hydration while on the drug is important, and sometimes drink sports drinks when I feel something coming on. For me, a day or two off the MEDs, taking tylenol, usually brings the fever down–but you should check with your doctor about this.

                        Good luck with it–

                        Paul

                        paul
                        Participant

                          I understand what you mean. A lot of the scans give false positives, making you freak out for nothing. And some of them aren't necessary in any sense (doctors often don't know what scan to order). And they aren't cheap, even with good insurance, once you're doing multiple scans 3-4 times a year. However, if there's something small there really is a benefit to seeing whether it's growing. If it's small, and doubles in size, you can be pretty sure you need it biopsied or removed, since the odds have gone up that it's something. Just want to say, mainly, as a person who as been through all the scenarios referred to above several times, that  I understand the impulse to wait for something to be symptomatic, but if you can afford the scans it may well lead to catching something earlier and having a less serious operation.

                          paul
                          Participant

                            I understand what you mean. A lot of the scans give false positives, making you freak out for nothing. And some of them aren't necessary in any sense (doctors often don't know what scan to order). And they aren't cheap, even with good insurance, once you're doing multiple scans 3-4 times a year. However, if there's something small there really is a benefit to seeing whether it's growing. If it's small, and doubles in size, you can be pretty sure you need it biopsied or removed, since the odds have gone up that it's something. Just want to say, mainly, as a person who as been through all the scenarios referred to above several times, that  I understand the impulse to wait for something to be symptomatic, but if you can afford the scans it may well lead to catching something earlier and having a less serious operation.

                            paul
                            Participant

                              I understand what you mean. A lot of the scans give false positives, making you freak out for nothing. And some of them aren't necessary in any sense (doctors often don't know what scan to order). And they aren't cheap, even with good insurance, once you're doing multiple scans 3-4 times a year. However, if there's something small there really is a benefit to seeing whether it's growing. If it's small, and doubles in size, you can be pretty sure you need it biopsied or removed, since the odds have gone up that it's something. Just want to say, mainly, as a person who as been through all the scenarios referred to above several times, that  I understand the impulse to wait for something to be symptomatic, but if you can afford the scans it may well lead to catching something earlier and having a less serious operation.

                              paul
                              Participant

                                I understand what you mean. A lot of the scans give false positives, making you freak out for nothing. And some of them aren't necessary in any sense (doctors often don't know what scan to order). And they aren't cheap, even with good insurance, once you're doing multiple scans 3-4 times a year. However, if there's something small there really is a benefit to seeing whether it's growing. If it's small, and doubles in size, you can be pretty sure you need it biopsied or removed, since the odds have gone up that it's something. Just want to say, mainly, as a person who as been through all the scenarios referred to above several times, that  I understand the impulse to wait for something to be symptomatic, but if you can afford the scans it may well lead to catching something earlier and having a less serious operation.

                                paul
                                Participant

                                  I understand what you mean. A lot of the scans give false positives, making you freak out for nothing. And some of them aren't necessary in any sense (doctors often don't know what scan to order). And they aren't cheap, even with good insurance, once you're doing multiple scans 3-4 times a year. However, if there's something small there really is a benefit to seeing whether it's growing. If it's small, and doubles in size, you can be pretty sure you need it biopsied or removed, since the odds have gone up that it's something. Just want to say, mainly, as a person who as been through all the scenarios referred to above several times, that  I understand the impulse to wait for something to be symptomatic, but if you can afford the scans it may well lead to catching something earlier and having a less serious operation.

                                  paul
                                  Participant

                                    I understand what you mean. A lot of the scans give false positives, making you freak out for nothing. And some of them aren't necessary in any sense (doctors often don't know what scan to order). And they aren't cheap, even with good insurance, once you're doing multiple scans 3-4 times a year. However, if there's something small there really is a benefit to seeing whether it's growing. If it's small, and doubles in size, you can be pretty sure you need it biopsied or removed, since the odds have gone up that it's something. Just want to say, mainly, as a person who as been through all the scenarios referred to above several times, that  I understand the impulse to wait for something to be symptomatic, but if you can afford the scans it may well lead to catching something earlier and having a less serious operation.

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