The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

YERVOY (IPI, Ipilumumab) VS. Radiation – HELP

Forums General Melanoma Community YERVOY (IPI, Ipilumumab) VS. Radiation – HELP

  • Post
    prayin4cr
    Participant

    My father (age 71) was diagnosed with stage 4 Melanoma about 2 years ago.

    Treated with IL2 first – got rid of Melanoma in hus liver, and shrunk nodes

    Treated next with oncovex – mixed reaction – killed some tumor and some grew

    Resection – got most, but grew back on nodes

    Other treatment – some pill (forget name) – mixed – they did surgery on tumor – now has large gaping hole and substantial tumor, hard to heal

    My dad was with a great Melanoma specialist, but now is back with Kaiser's more general oncology.

    My father (age 71) was diagnosed with stage 4 Melanoma about 2 years ago.

    Treated with IL2 first – got rid of Melanoma in hus liver, and shrunk nodes

    Treated next with oncovex – mixed reaction – killed some tumor and some grew

    Resection – got most, but grew back on nodes

    Other treatment – some pill (forget name) – mixed – they did surgery on tumor – now has large gaping hole and substantial tumor, hard to heal

    My dad was with a great Melanoma specialist, but now is back with Kaiser's more general oncology.

    He was planning on doing Yervoy (was scheduled in 3 weeks to start)

    The Kaiser general oncologist is recommending Radiation instead of Yervoy (IPI). 

    To me and my mother, it seems like the Yervoy would be the better option.

    Any opinions would be welcome.

    Loading spinner
Viewing 3 reply threads
  • Replies
      nicoli
      Participant

      I am beginning radiation next week (on my scalp) to try to kill remaining melanoma cells after surgery. It is my understanding that radiation can kill melanoma CELLS, but tumors… not so much.  Can your oncologist contact a specialist to double check?

      Nicki, Stage 3b, scalp, wide excision with skin graft, SNB, neck dissection, local recurrence, biochemo, more extensive scalp surger (flap), radiation.

      Loading spinner
        ValinMtl
        Participant

        Like Nicki, my radiation was to 'hopefully' kill remaining melanoma cells in the area of my surgery.  And believe me it wasn't a walk in the park…the doctor was very aggressive using a 'bolus' to draw the treatment to the surface, so ended up with 2nd degree burns.  Alas, melanoma came back within 2 months as cutaneous melanoma (mucho on my leg by the time ipi trial was approved in September 2010). 

        Ipi/yervoy treats systemic melanoma (without knowing all the facts, I would assume your father is considered in this category).  Very little side affects…rather easy compared to interferon. Worked well to kill the cutaneous melanoma. Alas, mel raised its ugly head in the CT scan in November and the fight continues on from there…so I am back on 2nd round of ipi (2nd treatment yesterday).  Would I do ipi again, you betcha…it has lengthened my life so far and pray it continues to do so..hope it can, if not next trial will be IL 2 vs Dicarbazine (say a prayer that I get on the IL 2 arm..we live in Canada where IL 2 is not approved yet).  Wishing your father the best.  Val

        Loading spinner
        ValinMtl
        Participant

        Michael is right, I actually came running back to computer to add as a subscript…'these are just my thoughts, I would suggest getting a second opinion'…Val

        Loading spinner
        ValinMtl
        Participant

        Michael is right, I actually came running back to computer to add as a subscript…'these are just my thoughts, I would suggest getting a second opinion'…Val

        Loading spinner
        ValinMtl
        Participant

        Like Nicki, my radiation was to 'hopefully' kill remaining melanoma cells in the area of my surgery.  And believe me it wasn't a walk in the park…the doctor was very aggressive using a 'bolus' to draw the treatment to the surface, so ended up with 2nd degree burns.  Alas, melanoma came back within 2 months as cutaneous melanoma (mucho on my leg by the time ipi trial was approved in September 2010). 

        Ipi/yervoy treats systemic melanoma (without knowing all the facts, I would assume your father is considered in this category).  Very little side affects…rather easy compared to interferon. Worked well to kill the cutaneous melanoma. Alas, mel raised its ugly head in the CT scan in November and the fight continues on from there…so I am back on 2nd round of ipi (2nd treatment yesterday).  Would I do ipi again, you betcha…it has lengthened my life so far and pray it continues to do so..hope it can, if not next trial will be IL 2 vs Dicarbazine (say a prayer that I get on the IL 2 arm..we live in Canada where IL 2 is not approved yet).  Wishing your father the best.  Val

        Loading spinner
      nicoli
      Participant

      I am beginning radiation next week (on my scalp) to try to kill remaining melanoma cells after surgery. It is my understanding that radiation can kill melanoma CELLS, but tumors… not so much.  Can your oncologist contact a specialist to double check?

      Nicki, Stage 3b, scalp, wide excision with skin graft, SNB, neck dissection, local recurrence, biochemo, more extensive scalp surger (flap), radiation.

      Loading spinner
      MichaelFL
      Participant

      As the others have said, radiation is used to "clean up"or for pain management. Not sure why the onc is going for this.

      Maybe the onc feels he will not do well with the Yervoy due to his age?

      Perhaps discuss this further with the onc.

      Michael

      Loading spinner
      MichaelFL
      Participant

      As the others have said, radiation is used to "clean up"or for pain management. Not sure why the onc is going for this.

      Maybe the onc feels he will not do well with the Yervoy due to his age?

      Perhaps discuss this further with the onc.

      Michael

      Loading spinner
Viewing 3 reply threads
  • You must be logged in to reply to this topic.
About the MRF Patient Forum

The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.