Yervoy & Diarrhea
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Yervoy & Diarrhea

› Forums › General Melanoma Community › Yervoy & Diarrhea

  • Post
    • January 28, 2014 at 1:15 am
    Patina
    Participant

    My Mom has had some good results with Yervoy and tonight we found out that she may not have her 3rd infusion, which is scheduled for this week.

    She has had increasing issues with diarrhea with no stomach pain, chills…  Just a lot of diarrhea…  The doctor wants to look at her labs tomorrow, but it sounds like he wants to postphone or stop the Yervoy. 

    Has anyone here been found to have colitis and then put on steroids before resuming Yervoy?  Or once the Yervoy was stopped was there no hope to try it again?  

    The tumors on her neck and head have changed markedly and we are very concenred by this turn of events…

Viewing 17 reply threads
  • Replies
      • January 28, 2014 at 3:56 am
      Momrn5
      Participant

      Yes, there have been several people on this forum who have had diarrhea and also colitis that has put them in the hospital or on steroids. It is a symptom that seems to be somewhat frequent with the use of this drug.  Some have been put on steroids to combat this issue. Good Luck to your mom!  

      • January 28, 2014 at 3:56 am
      Momrn5
      Participant

      Yes, there have been several people on this forum who have had diarrhea and also colitis that has put them in the hospital or on steroids. It is a symptom that seems to be somewhat frequent with the use of this drug.  Some have been put on steroids to combat this issue. Good Luck to your mom!  

      • January 28, 2014 at 3:56 am
      Momrn5
      Participant

      Yes, there have been several people on this forum who have had diarrhea and also colitis that has put them in the hospital or on steroids. It is a symptom that seems to be somewhat frequent with the use of this drug.  Some have been put on steroids to combat this issue. Good Luck to your mom!  

      • January 28, 2014 at 4:12 am
      Swanee
      Participant

      I did not do well on yervoy, stopping after 1 dose with ulcerated colitis, but apparently I am the 2% that could not tolerate.

      However, many here have had the difficulties you describe and were able to manage with steroids, diet and other drugs, taking a break from yervoy until things cleared up and then resuming their infusions.  I'm sure you will hear from those patients soon, who can give you a clear and concise report of their treatment details and direction.

      I'm happy for your Mom that she is doing otherwise well with yervoy and is showing all the good signs that she is responding!  Hopefully, she will be able to complete all the infusions with  aid of other medications!

      Sending positive thoughts to you and your Mom!

      Swanee

      • January 28, 2014 at 4:12 am
      Swanee
      Participant

      I did not do well on yervoy, stopping after 1 dose with ulcerated colitis, but apparently I am the 2% that could not tolerate.

      However, many here have had the difficulties you describe and were able to manage with steroids, diet and other drugs, taking a break from yervoy until things cleared up and then resuming their infusions.  I'm sure you will hear from those patients soon, who can give you a clear and concise report of their treatment details and direction.

      I'm happy for your Mom that she is doing otherwise well with yervoy and is showing all the good signs that she is responding!  Hopefully, she will be able to complete all the infusions with  aid of other medications!

      Sending positive thoughts to you and your Mom!

      Swanee

      • January 28, 2014 at 4:12 am
      Swanee
      Participant

      I did not do well on yervoy, stopping after 1 dose with ulcerated colitis, but apparently I am the 2% that could not tolerate.

      However, many here have had the difficulties you describe and were able to manage with steroids, diet and other drugs, taking a break from yervoy until things cleared up and then resuming their infusions.  I'm sure you will hear from those patients soon, who can give you a clear and concise report of their treatment details and direction.

      I'm happy for your Mom that she is doing otherwise well with yervoy and is showing all the good signs that she is responding!  Hopefully, she will be able to complete all the infusions with  aid of other medications!

      Sending positive thoughts to you and your Mom!

      Swanee

      • January 28, 2014 at 11:31 pm
      gostan
      Participant

      I had two IPI infusions and then two separate colitis tracks that each resulted in a10 day November hospital stay and an 8 day December hospital stay.  Steroids/prednisone were prescribed in each instance but they did not help.  Two Remicaid infusions finally did the trick.  My oncologist will not put me back on the IPI due to these side effects, but right now the underlying disease is stabilized.  and, of course, there are other treatment options if it does not stay stable. Overall, I have been told tht the prednisone not working on my colitis .   Best of luck to your mom.

      • January 28, 2014 at 11:31 pm
      gostan
      Participant

      I had two IPI infusions and then two separate colitis tracks that each resulted in a10 day November hospital stay and an 8 day December hospital stay.  Steroids/prednisone were prescribed in each instance but they did not help.  Two Remicaid infusions finally did the trick.  My oncologist will not put me back on the IPI due to these side effects, but right now the underlying disease is stabilized.  and, of course, there are other treatment options if it does not stay stable. Overall, I have been told tht the prednisone not working on my colitis .   Best of luck to your mom.

      • January 28, 2014 at 11:31 pm
      gostan
      Participant

      I had two IPI infusions and then two separate colitis tracks that each resulted in a10 day November hospital stay and an 8 day December hospital stay.  Steroids/prednisone were prescribed in each instance but they did not help.  Two Remicaid infusions finally did the trick.  My oncologist will not put me back on the IPI due to these side effects, but right now the underlying disease is stabilized.  and, of course, there are other treatment options if it does not stay stable. Overall, I have been told tht the prednisone not working on my colitis .   Best of luck to your mom.

      • January 29, 2014 at 5:05 am
      Marianne quinn
      Participant

      My husband had 2doses of 10 mg/kg ifusion. No diarrhea. Been on a diverticulosis diet- no seeds, nuts, popcorn. Eating bananas, making smoothies. Only has had a mild rash. He gets his 3 rd dose in 2 weeks. He is stage3c  NED.  Good luck to you

      • January 29, 2014 at 5:05 am
      Marianne quinn
      Participant

      My husband had 2doses of 10 mg/kg ifusion. No diarrhea. Been on a diverticulosis diet- no seeds, nuts, popcorn. Eating bananas, making smoothies. Only has had a mild rash. He gets his 3 rd dose in 2 weeks. He is stage3c  NED.  Good luck to you

      • January 29, 2014 at 5:05 am
      Marianne quinn
      Participant

      My husband had 2doses of 10 mg/kg ifusion. No diarrhea. Been on a diverticulosis diet- no seeds, nuts, popcorn. Eating bananas, making smoothies. Only has had a mild rash. He gets his 3 rd dose in 2 weeks. He is stage3c  NED.  Good luck to you

      • January 29, 2014 at 4:54 pm
      Dave from Ormond
      Participant

      My Oncologist put me on Diphan/Atrop after a week of the Yervoy diarrhea and that seemed to nip it immediately.  None of the over the counter products or any home remedies did anything.

      You should ask your Doctor to prescribe that for your Mom immediately before it becomes a bigger issue.

       

      • January 29, 2014 at 4:54 pm
      Dave from Ormond
      Participant

      My Oncologist put me on Diphan/Atrop after a week of the Yervoy diarrhea and that seemed to nip it immediately.  None of the over the counter products or any home remedies did anything.

      You should ask your Doctor to prescribe that for your Mom immediately before it becomes a bigger issue.

       

      • January 29, 2014 at 4:54 pm
      Dave from Ormond
      Participant

      My Oncologist put me on Diphan/Atrop after a week of the Yervoy diarrhea and that seemed to nip it immediately.  None of the over the counter products or any home remedies did anything.

      You should ask your Doctor to prescribe that for your Mom immediately before it becomes a bigger issue.

       

      • January 30, 2014 at 3:52 am
      FayFighter
      Participant

      my husband finished his last yervoy dec. 20 and has diarrhea and now colitis since dec. 24.  we have tried steroids to no avail. he will get remicaid treatment this friday.  we hope it will help with his symptoms.  re; your moms tumors….sometimes yervoy has a delayed response.

       

      • January 30, 2014 at 3:52 am
      FayFighter
      Participant

      my husband finished his last yervoy dec. 20 and has diarrhea and now colitis since dec. 24.  we have tried steroids to no avail. he will get remicaid treatment this friday.  we hope it will help with his symptoms.  re; your moms tumors….sometimes yervoy has a delayed response.

       

        • March 22, 2014 at 8:51 am
        ReginaTink
        Participant

        Has anyone experienced constipation first with yervoy then diarrhea.  I finished my last dosage of yervoy this past week and needed to take miralax for my constipation.  Now over the last three days, I have diarrhea and have been trying to control my stomach discomfort and diarrhea with pepto-bismal.  I will call the doctor if this diarrhea does no subside by monday. ReginaTink

        • March 22, 2014 at 8:51 am
        ReginaTink
        Participant

        Has anyone experienced constipation first with yervoy then diarrhea.  I finished my last dosage of yervoy this past week and needed to take miralax for my constipation.  Now over the last three days, I have diarrhea and have been trying to control my stomach discomfort and diarrhea with pepto-bismal.  I will call the doctor if this diarrhea does no subside by monday. ReginaTink

        • March 22, 2014 at 8:51 am
        ReginaTink
        Participant

        Has anyone experienced constipation first with yervoy then diarrhea.  I finished my last dosage of yervoy this past week and needed to take miralax for my constipation.  Now over the last three days, I have diarrhea and have been trying to control my stomach discomfort and diarrhea with pepto-bismal.  I will call the doctor if this diarrhea does no subside by monday. ReginaTink

      • January 30, 2014 at 3:52 am
      FayFighter
      Participant

      my husband finished his last yervoy dec. 20 and has diarrhea and now colitis since dec. 24.  we have tried steroids to no avail. he will get remicaid treatment this friday.  we hope it will help with his symptoms.  re; your moms tumors….sometimes yervoy has a delayed response.

       

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