Tafinlar

Hoping and praying that you have a great response with minimal side effects.  Do keep us posted.  Stay out of the hospital.  🙂

One day at a time.

Stay Strong

King/Kathie

Stage IV 7/05 Liver mets

Hoping and praying that you have a great response with minimal side effects.  Do keep us posted.  Stay out of the hospital.  🙂

One day at a time.

Stay Strong

King/Kathie

Stage IV 7/05 Liver mets

Hoping and praying that you have a great response with minimal side effects.  Do keep us posted.  Stay out of the hospital.  🙂

One day at a time.

Stay Strong

King/Kathie

Stage IV 7/05 Liver mets

Karen, good to hear from you. I cross my fingers, hope you will have a great response.

All the best, Jenny

Karen, good to hear from you. I cross my fingers, hope you will have a great response.

All the best, Jenny

Karen, good to hear from you. I cross my fingers, hope you will have a great response.

All the best, Jenny

Hi, Karen-

Under the circumstances I think that I would be "nervous and excited", too. I'm casting a strong "whammy" your way that the Taflinar works for you quickly and with very few side effects. 

I am a little confused, though. I thought you were going to participate in the Merck anti-PD1 trial but now you're taking Tafinlar (dabrafenib)? Did you change your mind about the PD-1 trial or are you going to try that later or what? 

Anyway, I have high hopes for the Tafinlar. You go, girl! WHAMMY!! 

Hi, Karen-

Under the circumstances I think that I would be "nervous and excited", too. I'm casting a strong "whammy" your way that the Taflinar works for you quickly and with very few side effects. 

I am a little confused, though. I thought you were going to participate in the Merck anti-PD1 trial but now you're taking Tafinlar (dabrafenib)? Did you change your mind about the PD-1 trial or are you going to try that later or what? 

Anyway, I have high hopes for the Tafinlar. You go, girl! WHAMMY!! 

Hi, Karen-

Under the circumstances I think that I would be "nervous and excited", too. I'm casting a strong "whammy" your way that the Taflinar works for you quickly and with very few side effects. 

I am a little confused, though. I thought you were going to participate in the Merck anti-PD1 trial but now you're taking Tafinlar (dabrafenib)? Did you change your mind about the PD-1 trial or are you going to try that later or what? 

Anyway, I have high hopes for the Tafinlar. You go, girl! WHAMMY!! 

Hi,

I posted on my experience with the Tafinlar-Mekinist combo a week or so ago.  I've now been on it for 3 weeks.  Recognizing that the treatment is only a "bridge", I've had outstanding results.  A subcutaneous tumor on my shoulder (4 cm) started to shrink within 2-3 days (it is now almost gone) and I also started to "feel better" within that same time frame–give it at least a week, however.  The organ that was most "at risk" for me was the liver–and I had a decent amount of liver sensation/pain, particularly in bed.  Gone within a week!  And my liver functions are now essentially normal.  I also had a small brain met that was identified before I started the combo.  I had it gamma-knifed last week and the MRI showed that it had shrunk by 25% while I was on the combo.  On the other hand, I developed a jaw tumor before I started the combo and lost some feeling in my mouth.  The combo has not (yet) resolved that.  A minor nuisance in the scheme of things.

As for side effects–keep in mind that I'm on the combo, not Tafinlar alone.  Hopefully I'm not jinxing myself, but I have had very few side effects.  Some joint pain (particularly hips) early on, but that seems to have resolved.  Some "skin thickening" on my forehead.  Minor and manageable stuff. 

I hope you get similar results and have an easy time with any side effects.

Mat

Hi,

I posted on my experience with the Tafinlar-Mekinist combo a week or so ago.  I've now been on it for 3 weeks.  Recognizing that the treatment is only a "bridge", I've had outstanding results.  A subcutaneous tumor on my shoulder (4 cm) started to shrink within 2-3 days (it is now almost gone) and I also started to "feel better" within that same time frame–give it at least a week, however.  The organ that was most "at risk" for me was the liver–and I had a decent amount of liver sensation/pain, particularly in bed.  Gone within a week!  And my liver functions are now essentially normal.  I also had a small brain met that was identified before I started the combo.  I had it gamma-knifed last week and the MRI showed that it had shrunk by 25% while I was on the combo.  On the other hand, I developed a jaw tumor before I started the combo and lost some feeling in my mouth.  The combo has not (yet) resolved that.  A minor nuisance in the scheme of things.

As for side effects–keep in mind that I'm on the combo, not Tafinlar alone.  Hopefully I'm not jinxing myself, but I have had very few side effects.  Some joint pain (particularly hips) early on, but that seems to have resolved.  Some "skin thickening" on my forehead.  Minor and manageable stuff. 

I hope you get similar results and have an easy time with any side effects.

Mat

Hi,

I posted on my experience with the Tafinlar-Mekinist combo a week or so ago.  I've now been on it for 3 weeks.  Recognizing that the treatment is only a "bridge", I've had outstanding results.  A subcutaneous tumor on my shoulder (4 cm) started to shrink within 2-3 days (it is now almost gone) and I also started to "feel better" within that same time frame–give it at least a week, however.  The organ that was most "at risk" for me was the liver–and I had a decent amount of liver sensation/pain, particularly in bed.  Gone within a week!  And my liver functions are now essentially normal.  I also had a small brain met that was identified before I started the combo.  I had it gamma-knifed last week and the MRI showed that it had shrunk by 25% while I was on the combo.  On the other hand, I developed a jaw tumor before I started the combo and lost some feeling in my mouth.  The combo has not (yet) resolved that.  A minor nuisance in the scheme of things.

As for side effects–keep in mind that I'm on the combo, not Tafinlar alone.  Hopefully I'm not jinxing myself, but I have had very few side effects.  Some joint pain (particularly hips) early on, but that seems to have resolved.  Some "skin thickening" on my forehead.  Minor and manageable stuff. 

I hope you get similar results and have an easy time with any side effects.

Mat

Amy

Amy

Amy