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Tafinlar Mekinist Joint Pain

Forums General Melanoma Community Tafinlar Mekinist Joint Pain

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      I will give you the basics. I am a 51 year old female. Most recent diagnosis is stage IV. I’ve been on Mekinist and Tafinlar (3 pills of each per day) since August 2020. I have been NED since January 2021. I recently purposely lost 35 pounds (and counting) because I decided if I was going to live, I want to feel and look better. I am off all prednisone now because the inflammation was gone. But, recently, the joint and muscle pain has come back in full force. Knees, hips, back, arms, neck. I used to do CrossFit and loved it and chose to stop due to this diagnosis and side effects. I feel like I am doing CrossFit again with the amount of pain I’ve been in.
      I get scans and MRIs every three months. I see oncologist and do labs monthly.
      Has anyone else experienced this type of joint pain on these meds? If so, ideas? Thoughts?
      Thank you, Theresa
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          I’ve been on TAF/MEK for about one year, and I haven’t had joint pain. Fevers, sweats, fatigue, and a few other things, but no joint pain. But my guess would be that it could be due to your medicine. I think the secondary effects can manifest itself in many forms.

          Congrats on the weight loss. That’s a good amount to shed; wish I could. 😉

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