Hello everybody,
I first want to thank you for all your support, it kept me sane for the past year, until we finally scored our very first success last month! Yeaay 🙂
My mom is 72 years old, she was diagnosed a year ago with stage IV melanoma, skin and lymphnodes. Her genetic tests showed BRAF+ and NO PD-L1 expression. However, we started treatment with "Opdivo" for 6 months hoping for the best, but with no success. So we switched to "Zelboraf" which showed regression of all tumors.
The reason we used "Zelboraf" only was the inavailability of "combo drugs" at that time. However, now after tons of paperwork, we finally could get Tafinlar+Mekinist available.
My question is:
"Given that "Z" is going well now , and with manageable side effects (finally). What should we do?"
1. Should we switch to the new combo "Tafinlar+Mekinist" hoping for better results, and yet taking the risk of losing track with "Z"?
2. Should we add "Keytruda" right away to the targeted therapy we choose for better results? Or should we wait until we run our course with it? i.e. progression?
3. Is there is anything we should do? I am already trying to find suitable clinical trials
I am just worried because we are nationals and residents of an African Country where melanoma is minimal and threfeore its treatments are not registered with local MOH, so they take months to get and I want to be one step ahead.
Thank you fo reading so far, looking forward to know your insights 🙂
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