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PD1 after Ipi – Experiences?
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PD1 after Ipi – Experiences?

› Forums › General Melanoma Community › PD1 after Ipi – Experiences?

  • Post
    • January 17, 2013 at 10:15 pm
    Erinmay22
    Participant

       

      I'm getting ready to start PD1 on Monday.  Had biopsy and new scans taken yesterday (still haven't heard how much my scans have changed in the last 4 weeks…).  
       
      Curious to hear from folks that took Ipi and failed and then took pd1?  What type of results did you see?  I know I've read a number of different things…  

       

      I'm getting ready to start PD1 on Monday.  Had biopsy and new scans taken yesterday (still haven't heard how much my scans have changed in the last 4 weeks…).  
       
      Curious to hear from folks that took Ipi and failed and then took pd1?  What type of results did you see?  I know I've read a number of different things…  
    Viewing 8 reply threads
    • Replies
        • January 18, 2013 at 1:24 am
        audgator
        Participant

          My mets grew on ipi and have been shrinking since I started PD1.  I'm into the every-3-months phase now. I wish you the best of responses.   Dan

          • January 18, 2013 at 1:24 am
          audgator
          Participant

            My mets grew on ipi and have been shrinking since I started PD1.  I'm into the every-3-months phase now. I wish you the best of responses.   Dan

            • January 18, 2013 at 1:24 am
            audgator
            Participant

              My mets grew on ipi and have been shrinking since I started PD1.  I'm into the every-3-months phase now. I wish you the best of responses.   Dan

              • January 18, 2013 at 2:09 am
              POW
              Participant

                Dr. Gibney at Moffitt told me the other day that they are now limiting anti-PD-1 clinical trials to people who have already tried ipi. I don't know why, but I assume that anti-PD-1 works well after ipi, maybe even better than before ipi. 

                  • January 18, 2013 at 2:30 am
                  Erinmay22
                  Participant

                    thanks guys!  just curious what folks experiences have been so far.  This will be my 3rd treatment I'm trying!  Ready to get started.  The trial nurse did say they are hoping this can be a 1-2 punch with ipi.  The other arms of the trial that I'm in combine ipi and pd1.  But since I've already had it I'll just do the pd1 arm of it.

                    I'll keep you posted.  

                    • January 18, 2013 at 2:30 am
                    Erinmay22
                    Participant

                      thanks guys!  just curious what folks experiences have been so far.  This will be my 3rd treatment I'm trying!  Ready to get started.  The trial nurse did say they are hoping this can be a 1-2 punch with ipi.  The other arms of the trial that I'm in combine ipi and pd1.  But since I've already had it I'll just do the pd1 arm of it.

                      I'll keep you posted.  

                      • January 18, 2013 at 2:30 am
                      Erinmay22
                      Participant

                        thanks guys!  just curious what folks experiences have been so far.  This will be my 3rd treatment I'm trying!  Ready to get started.  The trial nurse did say they are hoping this can be a 1-2 punch with ipi.  The other arms of the trial that I'm in combine ipi and pd1.  But since I've already had it I'll just do the pd1 arm of it.

                        I'll keep you posted.  

                        • January 18, 2013 at 4:12 pm
                        Erinmay22
                        Participant

                          FYI – found out the results of my scan today!! Since Dec 18th the tumor (lymph node) has shrunk! From 3.7 cm to 2.8 cm! and still nothing new! The best news is that they are still going to allow me in the pd1 clinical trial! First dose on Monday!

                          • January 18, 2013 at 4:12 pm
                          Erinmay22
                          Participant

                            FYI – found out the results of my scan today!! Since Dec 18th the tumor (lymph node) has shrunk! From 3.7 cm to 2.8 cm! and still nothing new! The best news is that they are still going to allow me in the pd1 clinical trial! First dose on Monday!

                            • January 18, 2013 at 5:53 pm
                            awillett1991
                            Participant
                              Yay!!! Go Erin!! Best news I’ve heard all day!!

                              Have a great weekend – I know you will!

                              • January 18, 2013 at 5:53 pm
                              awillett1991
                              Participant
                                Yay!!! Go Erin!! Best news I’ve heard all day!!

                                Have a great weekend – I know you will!

                                • January 18, 2013 at 5:53 pm
                                awillett1991
                                Participant
                                  Yay!!! Go Erin!! Best news I’ve heard all day!!

                                  Have a great weekend – I know you will!

                                  • January 19, 2013 at 12:28 am
                                  Tina D
                                  Participant

                                    YAY!! Amy told me you had gotten good news, so I had to come find it 🙂  . This is fantastic all the way around. So So happy! Enjoy your weekend!!

                                    Tina

                                    • January 20, 2013 at 2:47 pm
                                    Erinmay22
                                    Participant

                                      Tina – thanks!!  🙂  Hope you're having a great weekend!

                                      • January 20, 2013 at 2:47 pm
                                      Erinmay22
                                      Participant

                                        Tina – thanks!!  🙂  Hope you're having a great weekend!

                                        • January 20, 2013 at 2:47 pm
                                        Erinmay22
                                        Participant

                                          Tina – thanks!!  🙂  Hope you're having a great weekend!

                                          • January 19, 2013 at 12:28 am
                                          Tina D
                                          Participant

                                            YAY!! Amy told me you had gotten good news, so I had to come find it 🙂  . This is fantastic all the way around. So So happy! Enjoy your weekend!!

                                            Tina

                                            • January 19, 2013 at 12:28 am
                                            Tina D
                                            Participant

                                              YAY!! Amy told me you had gotten good news, so I had to come find it 🙂  . This is fantastic all the way around. So So happy! Enjoy your weekend!!

                                              Tina

                                              • January 18, 2013 at 4:12 pm
                                              Erinmay22
                                              Participant

                                                FYI – found out the results of my scan today!! Since Dec 18th the tumor (lymph node) has shrunk! From 3.7 cm to 2.8 cm! and still nothing new! The best news is that they are still going to allow me in the pd1 clinical trial! First dose on Monday!

                                                • January 18, 2013 at 7:54 pm
                                                POW
                                                Participant

                                                  Erin, that's wonderful news! Actually, BOTH pieces of news– the shrinking tumors AND the PD-1!! Praying for your best response yet!

                                                  • January 18, 2013 at 7:54 pm
                                                  POW
                                                  Participant

                                                    Erin, that's wonderful news! Actually, BOTH pieces of news– the shrinking tumors AND the PD-1!! Praying for your best response yet!

                                                    • January 18, 2013 at 7:54 pm
                                                    POW
                                                    Participant

                                                      Erin, that's wonderful news! Actually, BOTH pieces of news– the shrinking tumors AND the PD-1!! Praying for your best response yet!

                                                    • January 18, 2013 at 2:09 am
                                                    POW
                                                    Participant

                                                      Dr. Gibney at Moffitt told me the other day that they are now limiting anti-PD-1 clinical trials to people who have already tried ipi. I don't know why, but I assume that anti-PD-1 works well after ipi, maybe even better than before ipi. 

                                                      • January 18, 2013 at 2:09 am
                                                      POW
                                                      Participant

                                                        Dr. Gibney at Moffitt told me the other day that they are now limiting anti-PD-1 clinical trials to people who have already tried ipi. I don't know why, but I assume that anti-PD-1 works well after ipi, maybe even better than before ipi. 

                                                        • February 4, 2013 at 4:12 am
                                                        Erinlisay38
                                                        Participant
                                                          Hi I had Ippi didn’t respond every tumor grew a lot and now have a few new I just had scans blood work and biopsy done last week to get on the PD1 trial I’m just waiting on the call to tell me when I can start I’m getting nervous because I can actually feel changes tumors growing hopeful this may be the answer for us who have failed for the most part on Ipp
                                                            • February 12, 2013 at 12:58 am
                                                            Erinlisay38
                                                            Participant
                                                              So update I start my pd1 tomorrow 11:30 am Yay fingers and toes crossed for this treatment to work 🙂
                                                              • February 12, 2013 at 12:58 am
                                                              Erinlisay38
                                                              Participant
                                                                So update I start my pd1 tomorrow 11:30 am Yay fingers and toes crossed for this treatment to work 🙂
                                                                • February 12, 2013 at 12:58 am
                                                                Erinlisay38
                                                                Participant
                                                                  So update I start my pd1 tomorrow 11:30 am Yay fingers and toes crossed for this treatment to work 🙂
                                                                  • February 12, 2013 at 12:59 am
                                                                  Erinlisay38
                                                                  Participant
                                                                    So update I start my pd1 tomorrow 11:30 am Yay fingers and toes crossed for this treatment to work 🙂
                                                                    • February 18, 2013 at 3:12 pm
                                                                    Sandy11
                                                                    Participant

                                                                      Hi Erin,

                                                                      My husband started IPI a couple of months after you.  He has numerous lung mets and the most recent scan shows possible mets just outside his pancreas.  The good news, growth rate on the lung mets appear to have slowed… not shrunk, but slowed down a bit.  We'll take it.  He has a follow up scan to verify the new activity in March.  We had wondered about a possible "next step".  Sounds like PD1 has potential for better results.  Thanks for paving the way and the best of success to you.

                                                                      • February 18, 2013 at 3:12 pm
                                                                      Sandy11
                                                                      Participant

                                                                        Hi Erin,

                                                                        My husband started IPI a couple of months after you.  He has numerous lung mets and the most recent scan shows possible mets just outside his pancreas.  The good news, growth rate on the lung mets appear to have slowed… not shrunk, but slowed down a bit.  We'll take it.  He has a follow up scan to verify the new activity in March.  We had wondered about a possible "next step".  Sounds like PD1 has potential for better results.  Thanks for paving the way and the best of success to you.

                                                                        • February 18, 2013 at 3:12 pm
                                                                        Sandy11
                                                                        Participant

                                                                          Hi Erin,

                                                                          My husband started IPI a couple of months after you.  He has numerous lung mets and the most recent scan shows possible mets just outside his pancreas.  The good news, growth rate on the lung mets appear to have slowed… not shrunk, but slowed down a bit.  We'll take it.  He has a follow up scan to verify the new activity in March.  We had wondered about a possible "next step".  Sounds like PD1 has potential for better results.  Thanks for paving the way and the best of success to you.

                                                                          • February 12, 2013 at 12:59 am
                                                                          Erinlisay38
                                                                          Participant
                                                                            So update I start my pd1 tomorrow 11:30 am Yay fingers and toes crossed for this treatment to work 🙂
                                                                            • February 12, 2013 at 12:59 am
                                                                            Erinlisay38
                                                                            Participant
                                                                              So update I start my pd1 tomorrow 11:30 am Yay fingers and toes crossed for this treatment to work 🙂
                                                                            • February 4, 2013 at 4:12 am
                                                                            Erinlisay38
                                                                            Participant
                                                                              Hi I had Ippi didn’t respond every tumor grew a lot and now have a few new I just had scans blood work and biopsy done last week to get on the PD1 trial I’m just waiting on the call to tell me when I can start I’m getting nervous because I can actually feel changes tumors growing hopeful this may be the answer for us who have failed for the most part on Ipp
                                                                              • February 4, 2013 at 4:12 am
                                                                              Erinlisay38
                                                                              Participant
                                                                                Hi I had Ippi didn’t respond every tumor grew a lot and now have a few new I just had scans blood work and biopsy done last week to get on the PD1 trial I’m just waiting on the call to tell me when I can start I’m getting nervous because I can actually feel changes tumors growing hopeful this may be the answer for us who have failed for the most part on Ipp
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