NRAS mutation
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NRAS mutation

› Forums › General Melanoma Community › NRAS mutation

  • Post
    • June 1, 2015 at 12:51 pm
    mary1233
    Participant

    Can anyone clarify this for me?

    If someone has the NRAS mutation, is that considered wild-type?

    Thank you.

Viewing 2 reply threads
  • Replies
      • June 2, 2015 at 2:40 am
      kylez
      Participant

      See this http://www.bio.miami.edu/dana/dox/wildtype.html

      With an NRAS mutation, and no BRAF mutation (I understand they're usually exclusive), someone's biopsy would be both:

      – BRAF wild type, and

      – NRAS mutated

       

        • June 2, 2015 at 1:02 pm
        mary1233
        Participant

        What I am trying to understand is if I was told that I was a wild type does that mean that I do not have the NRAS mutation?

        Thanks.

        • June 2, 2015 at 1:55 pm
        Janner
        Participant

        Wild type means no mutation.  Wild type is "normal".

        • June 2, 2015 at 2:02 pm
        mary1233
        Participant

        I was told that wild type was no mutation that has yet been identified.

        • June 2, 2015 at 10:16 pm
        kylez
        Participant

        If someone was told tjey were NRAS wild type that means no NRAS mutation.

        They can be both NRAS wild type and BRAF wild type — that means neither mutation is present.

        • June 2, 2015 at 10:16 pm
        kylez
        Participant

        If someone was told tjey were NRAS wild type that means no NRAS mutation.

        They can be both NRAS wild type and BRAF wild type — that means neither mutation is present.

        • June 2, 2015 at 10:16 pm
        kylez
        Participant

        If someone was told tjey were NRAS wild type that means no NRAS mutation.

        They can be both NRAS wild type and BRAF wild type — that means neither mutation is present.

        • June 2, 2015 at 10:39 pm
        kylez
        Participant

        It was confusing to me at first. I hope I'm explaining it less confusingly now.

        • June 2, 2015 at 10:39 pm
        kylez
        Participant

        It was confusing to me at first. I hope I'm explaining it less confusingly now.

        • June 2, 2015 at 10:39 pm
        kylez
        Participant

        It was confusing to me at first. I hope I'm explaining it less confusingly now.

        • June 2, 2015 at 2:02 pm
        mary1233
        Participant

        I was told that wild type was no mutation that has yet been identified.

        • June 2, 2015 at 2:02 pm
        mary1233
        Participant

        I was told that wild type was no mutation that has yet been identified.

        • June 2, 2015 at 1:55 pm
        Janner
        Participant

        Wild type means no mutation.  Wild type is "normal".

        • June 2, 2015 at 1:55 pm
        Janner
        Participant

        Wild type means no mutation.  Wild type is "normal".

        • June 2, 2015 at 1:02 pm
        mary1233
        Participant

        What I am trying to understand is if I was told that I was a wild type does that mean that I do not have the NRAS mutation?

        Thanks.

        • June 2, 2015 at 1:02 pm
        mary1233
        Participant

        What I am trying to understand is if I was told that I was a wild type does that mean that I do not have the NRAS mutation?

        Thanks.

      • June 2, 2015 at 2:40 am
      kylez
      Participant

      See this http://www.bio.miami.edu/dana/dox/wildtype.html

      With an NRAS mutation, and no BRAF mutation (I understand they're usually exclusive), someone's biopsy would be both:

      – BRAF wild type, and

      – NRAS mutated

       

      • June 2, 2015 at 2:40 am
      kylez
      Participant

      See this http://www.bio.miami.edu/dana/dox/wildtype.html

      With an NRAS mutation, and no BRAF mutation (I understand they're usually exclusive), someone's biopsy would be both:

      – BRAF wild type, and

      – NRAS mutated

       

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