New Video by Dr. Weber reviewing treatment options for metastatic melanoma

This topic has 8 replies, 7 voices, and was last updated 3 years, 2 months ago by Sdmotorcop.

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- May 21, 2020 at 2:21 am
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Mark_DC
Participant
I think its from a February presentation, but Dr. Hamid just posted a link to it. There are a couple of other videos too.
This seems a great survey of treatments but at the end he also started mentioning new trials, which sound promising.

Hope this is useful and that it was not already posted.

Good luck to everyone
Mark

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- - May 21, 2020 at 2:28 am
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  Mark_DC
  Participant
  https://youtu.be/icplmCpkWoA I think this is a presentation at the same event on targetted therapy
- - May 22, 2020 at 2:27 am
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  Brian j
  Participant
  Thanks Mark, Great Video…Where we’ve been, where we are, and whats coming down the pike. Might have missed it if you hadn’t posted it.
- - May 23, 2020 at 5:48 am
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  MelMel
  Participant
  The more times one hears data from different sources, the more impact it makes. There is also a certain degree of comfort and satisfaction knowing that maybe each of us have made the best decision in our treatments. The future definitely looks much brighter and more promising.
  Thank you for sharing!
  Melanie
- - May 25, 2020 at 2:23 am
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  BrianP
  Participant
  Great info. Always love me some straight shooting Dr. Weber wisdom.
- - January 24, 2021 at 2:55 pm
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  Rosiepup
  Participant
  Thanks for sharing Mark. I will have a look and see if I can see what Corrales with what’s on offer!🤞🙏 Sorry, I sound bitter and don’t mean to be!
  I wish I could share photos here for cheer up purposes. A fantastic friend brought round two, yes two! Delicious tray bakes! ❤️
- - January 25, 2021 at 7:47 am
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  tkoss
  Participant
  interesting comment about toxicty of combo vs. nivo…..
  
  given the statistical similarity of SR’s it would seem that there is a real judgment call on combo v. nivo , quality of life v. SR.
  
  is this true amongst doctors?
- - January 27, 2021 at 1:47 pm
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  Sdmotorcop
  Participant
  Did I hear Dr Weber correctly when he said if you are BRAF wild and you progress on IPI/Nivo that you are kind of hosed? I would hope they’d be looking into treatments for that also..
  - January 27, 2021 at 3:43 pm
    
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    ed williams
    Participant
    
    Hi there Sdmotorcop, there is a lot going on in this area but we are left waiting on phase three reporting. For example NKTR-214, Lag-3, TLR-9 and other interlesional injectable drugs, LN-144 Lifileucel TIL’s treatment is at FDA looking for approval and it has shown good uptake for patients that have progressed on Ipi+Nivo, gut microbiome trials, VEGF, Bispecfics, Oxphos at MD Anderson and there are many more in early phase combinations trying to find the next great thing. I would never argue with Dr. Weber, he is the best in the business, and in this case as far as melanoma patients that have progressed on ipi+nivo right now “today” he is telling it like it is, but there is a lot of hope on what is coming down the pipeline. Clinical trials would be the way to go, just hard to find a trial that is open and recruiting just when a patient might need it. Many travel and go to the big hospital like MD Anderson where they have a lot going on in many different research areas.
- - January 28, 2021 at 9:37 pm
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  Sdmotorcop
  Participant
  Thanks for encouraging news Ed. I went to stage 4 after 10 months of Nivo (lung, stomach and lymph node Mets). I did three doses of Ipi (June 20) before my liver started to go wonky. My last Pet was encouraging with a decrease in size of all Mets. I have a ct next week so I’m keeping my fingers crossed.