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Necrosis on PET/CT Bad or Good ???

Forums General Melanoma Community Necrosis on PET/CT Bad or Good ???

  • Post
    susanr
    Participant

      Hello Everyone,

      Hello Everyone,

      I see many posts re: PET/CT scans.  Many of the posts reveal necrosis within many organs. I see some post Brain, liver, lung, etc.  My brother just had his PET/CT this week and had necrosis at the center of a left pelvic mass along with some nodes containing necrosis.  Had yervoy 12/2011, just finished Temodor and Abraxane.  Some comments I hear that it can be a good sign, bad sign,  or no significance.  Any comments to help offer some in- sight.   Doctor did not even comment on this but I see so many of us post this ?  Thanks so much…!!!!!!

       

      Susan R.  NY

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    • Replies
        Janner
        Participant

          Necrosis means dead tissue – totally inactive.  I can't see anything other than it being a good sign as long as you're referring to melanoma tumors.  Certainly you wouldn't want to see it in healthy tissue, but it's a desirable trait in tumors!

          Janner
          Participant

            Necrosis means dead tissue – totally inactive.  I can't see anything other than it being a good sign as long as you're referring to melanoma tumors.  Certainly you wouldn't want to see it in healthy tissue, but it's a desirable trait in tumors!

              awillett1991
              Participant
                Here is what I was told concerning the necrotic center of a tumor ( was on no treatment at the time, and was told the mass was still growing): one doc said we have absolutely no idea what it means. Another doc explained it is not good or bad, often times it mans the tumor has outgrown the blood supply it is attached to, in other words the blood supply can’t support the entire tumor mass anymore. We chose to take it as a good sign! My most recent scan last week didn’t mention the necrotic tissue but did show tumor shrinkage due to Zelboraf. Best of luck to you!
                susanr
                Participant

                  I really appreciate your post.  This is why I posted this.  So many conflicting feed back from docs.

                  I am glad you had  this report from Zelboraf.  Very Happy you are a responder.  Best of luck to you also.  Keep us posted on your treatment……..

                   

                  thank you !!!!!!!!!!!!!

                  susanr
                  Participant

                    I really appreciate your post.  This is why I posted this.  So many conflicting feed back from docs.

                    I am glad you had  this report from Zelboraf.  Very Happy you are a responder.  Best of luck to you also.  Keep us posted on your treatment……..

                     

                    thank you !!!!!!!!!!!!!

                    susanr
                    Participant

                      I really appreciate your post.  This is why I posted this.  So many conflicting feed back from docs.

                      I am glad you had  this report from Zelboraf.  Very Happy you are a responder.  Best of luck to you also.  Keep us posted on your treatment……..

                       

                      thank you !!!!!!!!!!!!!

                      awillett1991
                      Participant
                        Here is what I was told concerning the necrotic center of a tumor ( was on no treatment at the time, and was told the mass was still growing): one doc said we have absolutely no idea what it means. Another doc explained it is not good or bad, often times it mans the tumor has outgrown the blood supply it is attached to, in other words the blood supply can’t support the entire tumor mass anymore. We chose to take it as a good sign! My most recent scan last week didn’t mention the necrotic tissue but did show tumor shrinkage due to Zelboraf. Best of luck to you!
                        awillett1991
                        Participant
                          Here is what I was told concerning the necrotic center of a tumor ( was on no treatment at the time, and was told the mass was still growing): one doc said we have absolutely no idea what it means. Another doc explained it is not good or bad, often times it mans the tumor has outgrown the blood supply it is attached to, in other words the blood supply can’t support the entire tumor mass anymore. We chose to take it as a good sign! My most recent scan last week didn’t mention the necrotic tissue but did show tumor shrinkage due to Zelboraf. Best of luck to you!
                          susanr
                          Participant

                            Thank you janner.   Yes, Its in a melanoma tumor.  Some of the docs are not impressed that it is a good trait….I would rather see this and hope the rest of the tumor will die.  Will see…Thank you

                            susanr
                            Participant

                              Thank you janner.   Yes, Its in a melanoma tumor.  Some of the docs are not impressed that it is a good trait….I would rather see this and hope the rest of the tumor will die.  Will see…Thank you

                              susanr
                              Participant

                                Thank you janner.   Yes, Its in a melanoma tumor.  Some of the docs are not impressed that it is a good trait….I would rather see this and hope the rest of the tumor will die.  Will see…Thank you

                              Janner
                              Participant

                                Necrosis means dead tissue – totally inactive.  I can't see anything other than it being a good sign as long as you're referring to melanoma tumors.  Certainly you wouldn't want to see it in healthy tissue, but it's a desirable trait in tumors!

                                LynnLuc
                                Participant

                                  My tumor by my superior vena cava was 6.8 cent. at the widest area and it was also partially necrotic when they removed it. The surgeon at Mayo said this was due to the previous radiation. It still had living cells but part of the melanoma was damaged by the radiation and died…unless its totally necrotic  it has the potential to grow and travel to other parts of the body.

                                    susanr
                                    Participant

                                      Thank you Lynn,

                                      I enjoy reading your posts and really appreciate responding to everyone.  I read your comments and saw your profile….you are a " warrior " !!!!!  Very happy for you and keep guiding all of us with your posts.

                                       

                                      Thanks

                                      SusanR NY 

                                      susanr
                                      Participant

                                        Thank you Lynn,

                                        I enjoy reading your posts and really appreciate responding to everyone.  I read your comments and saw your profile….you are a " warrior " !!!!!  Very happy for you and keep guiding all of us with your posts.

                                         

                                        Thanks

                                        SusanR NY 

                                        susanr
                                        Participant

                                          Thank you Lynn,

                                          I enjoy reading your posts and really appreciate responding to everyone.  I read your comments and saw your profile….you are a " warrior " !!!!!  Very happy for you and keep guiding all of us with your posts.

                                           

                                          Thanks

                                          SusanR NY 

                                        LynnLuc
                                        Participant

                                          My tumor by my superior vena cava was 6.8 cent. at the widest area and it was also partially necrotic when they removed it. The surgeon at Mayo said this was due to the previous radiation. It still had living cells but part of the melanoma was damaged by the radiation and died…unless its totally necrotic  it has the potential to grow and travel to other parts of the body.

                                          LynnLuc
                                          Participant

                                            My tumor by my superior vena cava was 6.8 cent. at the widest area and it was also partially necrotic when they removed it. The surgeon at Mayo said this was due to the previous radiation. It still had living cells but part of the melanoma was damaged by the radiation and died…unless its totally necrotic  it has the potential to grow and travel to other parts of the body.

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