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Mitosis
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Mitosis

› Forums › General Melanoma Community › Mitosis

  • Post
    • November 1, 2013 at 1:21 pm
    SBeattie
    Participant

      just curious if any of you smart, wonderful folk know if one is 'locked in' with mitotic rate of initial lesion…can it slow down, or speed up in subsequent lesions/metastasis? Haven't seen anything in the lit/research I've perused over the last 2  + yrs…however, I know it is a prognostic indicator of recurrence…thanks very much

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    • Replies
        • November 1, 2013 at 2:11 pm
        sharon0803
        Participant

          Great question!  I too wondered about this.

           

            • November 1, 2013 at 2:57 pm
            DebbieH
            Participant

              I wouldn't worry too much about it.  I've seen people with high mitotic rates with no recurrence and I've seen others with very low ones (like mine at less than 1) come back. 

              DebbieH, stage 3C, NED 12+ years after interferon and no scans

              • November 1, 2013 at 3:08 pm
              SBeattie
              Participant

                thank you…!

                • November 1, 2013 at 3:08 pm
                SBeattie
                Participant

                  thank you…!

                  • November 1, 2013 at 3:08 pm
                  SBeattie
                  Participant

                    thank you…!

                    • November 1, 2013 at 2:57 pm
                    DebbieH
                    Participant

                      I wouldn't worry too much about it.  I've seen people with high mitotic rates with no recurrence and I've seen others with very low ones (like mine at less than 1) come back. 

                      DebbieH, stage 3C, NED 12+ years after interferon and no scans

                      • November 1, 2013 at 2:57 pm
                      DebbieH
                      Participant

                        I wouldn't worry too much about it.  I've seen people with high mitotic rates with no recurrence and I've seen others with very low ones (like mine at less than 1) come back. 

                        DebbieH, stage 3C, NED 12+ years after interferon and no scans

                      • November 1, 2013 at 2:11 pm
                      sharon0803
                      Participant

                        Great question!  I too wondered about this.

                         

                        • November 1, 2013 at 2:11 pm
                        sharon0803
                        Participant

                          Great question!  I too wondered about this.

                           

                          • November 1, 2013 at 6:18 pm
                          Janner
                          Participant

                            Mitosis (in some circles) is still a bit controversial because if something is invasive, it implies that some mitosis exists.  In addition, it really depends what sample of tissue you look at.  Right now, it's only used in staging to distinguish between stage IA and stage IB.  It's really a newer prognostic factor and depth, to date, is still THE most important prognostic factor.   

                              • November 1, 2013 at 8:16 pm
                              SBeattie
                              Participant

                                Thank you!

                                • November 1, 2013 at 8:16 pm
                                SBeattie
                                Participant

                                  Thank you!

                                  • November 1, 2013 at 8:16 pm
                                  SBeattie
                                  Participant

                                    Thank you!

                                  • November 1, 2013 at 6:18 pm
                                  Janner
                                  Participant

                                    Mitosis (in some circles) is still a bit controversial because if something is invasive, it implies that some mitosis exists.  In addition, it really depends what sample of tissue you look at.  Right now, it's only used in staging to distinguish between stage IA and stage IB.  It's really a newer prognostic factor and depth, to date, is still THE most important prognostic factor.   

                                    • November 1, 2013 at 6:18 pm
                                    Janner
                                    Participant

                                      Mitosis (in some circles) is still a bit controversial because if something is invasive, it implies that some mitosis exists.  In addition, it really depends what sample of tissue you look at.  Right now, it's only used in staging to distinguish between stage IA and stage IB.  It's really a newer prognostic factor and depth, to date, is still THE most important prognostic factor.   

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