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Merck PD1 – a MIRACLE Drug!

Forums General Melanoma Community Merck PD1 – a MIRACLE Drug!

  • Post
    Candi13
    Participant
      Hi,
      
      I am posting my good news to share information on the Merck PD-1 trial.
      
      I started this trial on 12/20/11. After only 3 infusions, I could see 2 subq's on my leg and chest start shrinking.
      
      Last week, I had my first 12 week scans since starting to take this drug. My doctor told me that there was NO CANCER 
      anywhere in my body. 
      
      Starting the trial, I had tumors in my leg, on my chest and BOTH lungs. Being stage 4, this is truly a miracle after 
      only taking this drug for 12 weeks. My doctor told me, I am a “complete responder”.
      
      I know of 2 other patients who started this trial in December 2011 with me. One patient with lung mets is a complete 
      responder. The other patient is a partial responder.
      
      For those interested in this trial, here is the link:
      http://clinicaltrials.gov/ct2/show/NCT01295827
      
      I know that there are openings for this trial at UCLA Medical Center with Dr. Ribas. His email [email protected] 
      
      Good Luck to Everyone fighting Mel.
      
      Candi
    Viewing 44 reply threads
    • Replies
        audgator
        Participant

          Although no one is happier than you, I guarantee there are a LOT of happy people reading this, including me. Congrats.

          Dan

          audgator
          Participant

            Although no one is happier than you, I guarantee there are a LOT of happy people reading this, including me. Congrats.

            Dan

            audgator
            Participant

              Although no one is happier than you, I guarantee there are a LOT of happy people reading this, including me. Congrats.

              Dan

              Gene_S
              Participant

                Wow what wonderful news you received.  We are so happy for you.

                NED is one thing my husband keep hoping for also.  He is making progress but is really hoping one day he can add to his profile. NED.

                Sounds to me like it is time for you to celebrate.

                Judy (loving wife and caregiver of Gene Stage IV)

                Gene_S
                Participant

                  Wow what wonderful news you received.  We are so happy for you.

                  NED is one thing my husband keep hoping for also.  He is making progress but is really hoping one day he can add to his profile. NED.

                  Sounds to me like it is time for you to celebrate.

                  Judy (loving wife and caregiver of Gene Stage IV)

                  Gene_S
                  Participant

                    Wow what wonderful news you received.  We are so happy for you.

                    NED is one thing my husband keep hoping for also.  He is making progress but is really hoping one day he can add to his profile. NED.

                    Sounds to me like it is time for you to celebrate.

                    Judy (loving wife and caregiver of Gene Stage IV)

                    MaryD
                    Participant

                      Wow – that is fantastic news – so happy for you!    Thanks for sharing this as it will give hope to so many  . .and I wish you continued successful results!

                      Mary

                      MaryD
                      Participant

                        Wow – that is fantastic news – so happy for you!    Thanks for sharing this as it will give hope to so many  . .and I wish you continued successful results!

                        Mary

                        MaryD
                        Participant

                          Wow – that is fantastic news – so happy for you!    Thanks for sharing this as it will give hope to so many  . .and I wish you continued successful results!

                          Mary

                          yoopergirl
                          Participant

                            Such good news, I may be taking part in that PD 1 trial at the UW Madison, will have my scans on the 26th and go from there. You bring so much hope to all of us.

                            yoopergirl
                            Participant

                              Such good news, I may be taking part in that PD 1 trial at the UW Madison, will have my scans on the 26th and go from there. You bring so much hope to all of us.

                              yoopergirl
                              Participant

                                Such good news, I may be taking part in that PD 1 trial at the UW Madison, will have my scans on the 26th and go from there. You bring so much hope to all of us.

                                jim Breitfeller
                                Participant

                                  Candi, Congrats!!!

                                  Could you go though your time-line of therapies and doses with dates. I would like to see how it falls on a theoretical time scale. It is in my post called "Redirecting the Melanoma Tumor’s Microenvironment in Favor of the Activation of T-cells ". The second graphic.

                                  Thanks in advance

                                   

                                  Jimmy B

                                    Candi13
                                    Participant

                                      Jimmy,

                                       

                                      2009-leukine, 2010-temador, and multiple surgeries

                                       

                                      Candi

                                      Candi13
                                      Participant

                                        Jimmy,

                                         

                                        2009-leukine, 2010-temador, and multiple surgeries

                                         

                                        Candi

                                        Candi13
                                        Participant

                                          Jimmy,

                                           

                                          2009-leukine, 2010-temador, and multiple surgeries

                                           

                                          Candi

                                        jim Breitfeller
                                        Participant

                                          Candi, Congrats!!!

                                          Could you go though your time-line of therapies and doses with dates. I would like to see how it falls on a theoretical time scale. It is in my post called "Redirecting the Melanoma Tumor’s Microenvironment in Favor of the Activation of T-cells ". The second graphic.

                                          Thanks in advance

                                           

                                          Jimmy B

                                          jim Breitfeller
                                          Participant

                                            Candi, Congrats!!!

                                            Could you go though your time-line of therapies and doses with dates. I would like to see how it falls on a theoretical time scale. It is in my post called "Redirecting the Melanoma Tumor’s Microenvironment in Favor of the Activation of T-cells ". The second graphic.

                                            Thanks in advance

                                             

                                            Jimmy B

                                            rbruce
                                            Participant

                                              AWESOME News!!!!!!!!   I started this trial at UCSF on the 15th of this month and have been dreading having to wait 12 weeks to see if anything is working.  Having a really bad day today yand then I see your posting and turned my day around.  Thank you for sharing your wonderful news and I look forward to reading future posts about your continued great response.  Have you expereinced any side affects?  I had flu like symptoms, achey bones and muscles for a couple days after infusion but that seems to be gone.   Robert

                                                Candi13
                                                Participant

                                                  Hi Robert,

                                                   

                                                  Do you know if there are any openings a UCSF?? How often do you get infusions???

                                                   

                                                  Good Luck with this trial. I hope you are a complete responder.

                                                   

                                                  BettyJo

                                                  rbruce
                                                  Participant

                                                    BettyJo,

                                                    No openings right now, but they are trying to get additional seats so I would contact them and get on the list.

                                                    Robert

                                                    Candi13
                                                    Participant

                                                      Thanks Robert…how often do you have an infusion? how long is the infusion?  BettyJo

                                                      rbruce
                                                      Participant

                                                        Infusion only lasts about 30 minutes.  Clinic vist with Dr., blood test before and after then EKG after takes a total of about 2-3 hours at clinic.     Robert

                                                        killmel
                                                        Participant

                                                          how often are the infusions?

                                                          rbruce
                                                          Participant

                                                            every 2 weeks.

                                                            rbruce
                                                            Participant

                                                              every 2 weeks.

                                                              rbruce
                                                              Participant

                                                                every 2 weeks.

                                                                killmel
                                                                Participant

                                                                  how often are the infusions?

                                                                  killmel
                                                                  Participant

                                                                    how often are the infusions?

                                                                    rbruce
                                                                    Participant

                                                                      Infusion only lasts about 30 minutes.  Clinic vist with Dr., blood test before and after then EKG after takes a total of about 2-3 hours at clinic.     Robert

                                                                      rbruce
                                                                      Participant

                                                                        Infusion only lasts about 30 minutes.  Clinic vist with Dr., blood test before and after then EKG after takes a total of about 2-3 hours at clinic.     Robert

                                                                        Candi13
                                                                        Participant

                                                                          Thanks Robert…how often do you have an infusion? how long is the infusion?  BettyJo

                                                                          Candi13
                                                                          Participant

                                                                            Thanks Robert…how often do you have an infusion? how long is the infusion?  BettyJo

                                                                            rbruce
                                                                            Participant

                                                                              BettyJo,

                                                                              No openings right now, but they are trying to get additional seats so I would contact them and get on the list.

                                                                              Robert

                                                                              rbruce
                                                                              Participant

                                                                                BettyJo,

                                                                                No openings right now, but they are trying to get additional seats so I would contact them and get on the list.

                                                                                Robert

                                                                                Candi13
                                                                                Participant

                                                                                  Hi Robert,

                                                                                   

                                                                                  Do you know if there are any openings a UCSF?? How often do you get infusions???

                                                                                   

                                                                                  Good Luck with this trial. I hope you are a complete responder.

                                                                                   

                                                                                  BettyJo

                                                                                  Candi13
                                                                                  Participant

                                                                                    Hi Robert,

                                                                                     

                                                                                    Do you know if there are any openings a UCSF?? How often do you get infusions???

                                                                                     

                                                                                    Good Luck with this trial. I hope you are a complete responder.

                                                                                     

                                                                                    BettyJo

                                                                                  rbruce
                                                                                  Participant

                                                                                    AWESOME News!!!!!!!!   I started this trial at UCSF on the 15th of this month and have been dreading having to wait 12 weeks to see if anything is working.  Having a really bad day today yand then I see your posting and turned my day around.  Thank you for sharing your wonderful news and I look forward to reading future posts about your continued great response.  Have you expereinced any side affects?  I had flu like symptoms, achey bones and muscles for a couple days after infusion but that seems to be gone.   Robert

                                                                                    rbruce
                                                                                    Participant

                                                                                      AWESOME News!!!!!!!!   I started this trial at UCSF on the 15th of this month and have been dreading having to wait 12 weeks to see if anything is working.  Having a really bad day today yand then I see your posting and turned my day around.  Thank you for sharing your wonderful news and I look forward to reading future posts about your continued great response.  Have you expereinced any side affects?  I had flu like symptoms, achey bones and muscles for a couple days after infusion but that seems to be gone.   Robert

                                                                                      hope4cure1
                                                                                      Participant

                                                                                        Terrific, terrific,terrific! Thank you so much for sharing.  I'm raising a glass to your continued NED!!!

                                                                                        Hope

                                                                                        hope4cure1
                                                                                        Participant

                                                                                          Terrific, terrific,terrific! Thank you so much for sharing.  I'm raising a glass to your continued NED!!!

                                                                                          Hope

                                                                                          hope4cure1
                                                                                          Participant

                                                                                            Terrific, terrific,terrific! Thank you so much for sharing.  I'm raising a glass to your continued NED!!!

                                                                                            Hope

                                                                                            melmar
                                                                                            Participant

                                                                                              Congratulations!  Thanks for sharing the good news!

                                                                                              melmar
                                                                                              Participant

                                                                                                Congratulations!  Thanks for sharing the good news!

                                                                                                melmar
                                                                                                Participant

                                                                                                  Congratulations!  Thanks for sharing the good news!

                                                                                                  melmar
                                                                                                  Participant

                                                                                                    Congratulations!  Thanks for sharing the good news!

                                                                                                    melmar
                                                                                                    Participant

                                                                                                      Congratulations!  Thanks for sharing the good news!

                                                                                                      melmar
                                                                                                      Participant

                                                                                                        Congratulations!  Thanks for sharing the good news!

                                                                                                        Eileen L
                                                                                                        Participant

                                                                                                          Great news. Thx for posting. Gives all of us Stage 4 folks hope!

                                                                                                          Eileen L

                                                                                                          Eileen L
                                                                                                          Participant

                                                                                                            Great news. Thx for posting. Gives all of us Stage 4 folks hope!

                                                                                                            Eileen L

                                                                                                            Eileen L
                                                                                                            Participant

                                                                                                              Great news. Thx for posting. Gives all of us Stage 4 folks hope!

                                                                                                              Eileen L

                                                                                                              MeNDave
                                                                                                              Participant

                                                                                                                Congrats Candi!!  Doing a happy dance for you!  Thanks for posting the good news…. it gives many hope ๐Ÿ™‚

                                                                                                                MeNDave
                                                                                                                Participant

                                                                                                                  Congrats Candi!!  Doing a happy dance for you!  Thanks for posting the good news…. it gives many hope ๐Ÿ™‚

                                                                                                                  MeNDave
                                                                                                                  Participant

                                                                                                                    Congrats Candi!!  Doing a happy dance for you!  Thanks for posting the good news…. it gives many hope ๐Ÿ™‚

                                                                                                                    Drew N
                                                                                                                    Participant

                                                                                                                      Even though I'm not actively fighting C these days, it's amazing to hear about the progress in the last year. Plus, my secretary's MiL just started 3475 yesterday, and we now have positive experiences to think about.

                                                                                                                      Drew Nelson

                                                                                                                      3b since 1/09

                                                                                                                      Drew N
                                                                                                                      Participant

                                                                                                                        Even though I'm not actively fighting C these days, it's amazing to hear about the progress in the last year. Plus, my secretary's MiL just started 3475 yesterday, and we now have positive experiences to think about.

                                                                                                                        Drew Nelson

                                                                                                                        3b since 1/09

                                                                                                                        Drew N
                                                                                                                        Participant

                                                                                                                          Even though I'm not actively fighting C these days, it's amazing to hear about the progress in the last year. Plus, my secretary's MiL just started 3475 yesterday, and we now have positive experiences to think about.

                                                                                                                          Drew Nelson

                                                                                                                          3b since 1/09

                                                                                                                          Linny
                                                                                                                          Participant

                                                                                                                            What wonderful news! I hope you went out and celebrated. smiley

                                                                                                                              Candi13
                                                                                                                              Participant

                                                                                                                                Thank you all for the well wishes.

                                                                                                                                Update on results from Merck pd1 trial…I was told by my the study nurse today, that there were more patients having a partial response after their 12 weeks scans. Hopeful news for this drug!

                                                                                                                                Candi

                                                                                                                                Candi13
                                                                                                                                Participant

                                                                                                                                  Thank you all for the well wishes.

                                                                                                                                  Update on results from Merck pd1 trial…I was told by my the study nurse today, that there were more patients having a partial response after their 12 weeks scans. Hopeful news for this drug!

                                                                                                                                  Candi

                                                                                                                                  Candi13
                                                                                                                                  Participant

                                                                                                                                    Thank you all for the well wishes.

                                                                                                                                    Update on results from Merck pd1 trial…I was told by my the study nurse today, that there were more patients having a partial response after their 12 weeks scans. Hopeful news for this drug!

                                                                                                                                    Candi

                                                                                                                                  Linny
                                                                                                                                  Participant

                                                                                                                                    What wonderful news! I hope you went out and celebrated. smiley

                                                                                                                                    Linny
                                                                                                                                    Participant

                                                                                                                                      What wonderful news! I hope you went out and celebrated. smiley

                                                                                                                                      caseym
                                                                                                                                      Participant

                                                                                                                                        Hi everyone,

                                                                                                                                        I just wanted to see how you are all going on the PD1 trial? My mum is 3rd on the list for the second round of trials in Australia. I want to give her the good news that i have already read about this drug and also any more details that you can provide to me.

                                                                                                                                        I am so happy to hear that this trial seems to be working and so pleased to hear you are doing well Candi.

                                                                                                                                        Look forward to hearing from you

                                                                                                                                        caseym
                                                                                                                                        Participant

                                                                                                                                          Hi everyone,

                                                                                                                                          I just wanted to see how you are all going on the PD1 trial? My mum is 3rd on the list for the second round of trials in Australia. I want to give her the good news that i have already read about this drug and also any more details that you can provide to me.

                                                                                                                                          I am so happy to hear that this trial seems to be working and so pleased to hear you are doing well Candi.

                                                                                                                                          Look forward to hearing from you

                                                                                                                                          caseym
                                                                                                                                          Participant

                                                                                                                                            Hi everyone,

                                                                                                                                            I just wanted to see how you are all going on the PD1 trial? My mum is 3rd on the list for the second round of trials in Australia. I want to give her the good news that i have already read about this drug and also any more details that you can provide to me.

                                                                                                                                            I am so happy to hear that this trial seems to be working and so pleased to hear you are doing well Candi.

                                                                                                                                            Look forward to hearing from you

                                                                                                                                            melinda2
                                                                                                                                            Participant

                                                                                                                                              THANK YOU for your post that just gave me a big, bright spot in my day.  My husband is Stage IV and will start the Merck PD-1 trial at Emory in two weeks.  He completed Yervoy recently and his cancer did not respond to it at all.  For southeast folks, I am aware that the PD-1 trials are being done at Mayo in Jacksonville as well as Emory in Atlanta.  Don't know if Moffet in Tampa has a trial program.

                                                                                                                                              melinda2
                                                                                                                                              Participant

                                                                                                                                                THANK YOU for your post that just gave me a big, bright spot in my day.  My husband is Stage IV and will start the Merck PD-1 trial at Emory in two weeks.  He completed Yervoy recently and his cancer did not respond to it at all.  For southeast folks, I am aware that the PD-1 trials are being done at Mayo in Jacksonville as well as Emory in Atlanta.  Don't know if Moffet in Tampa has a trial program.

                                                                                                                                                melinda2
                                                                                                                                                Participant

                                                                                                                                                  THANK YOU for your post that just gave me a big, bright spot in my day.  My husband is Stage IV and will start the Merck PD-1 trial at Emory in two weeks.  He completed Yervoy recently and his cancer did not respond to it at all.  For southeast folks, I am aware that the PD-1 trials are being done at Mayo in Jacksonville as well as Emory in Atlanta.  Don't know if Moffet in Tampa has a trial program.

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