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Melanoma and Psoriasis

Forums General Melanoma Community Melanoma and Psoriasis

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      Hello lovely board:

      I’m wondering if anyone else on here has also had psoriasis and, if so:

      a) Did you have psoriasis treatment before your melanoma or after?

      b) If you had psoriasis treatment after your melanoma, how was your psoriasis treatment affected? Did the risk of additional melanoma prevent you from taking the medications/treatments you needed to make your psoriasis / psoriatric arthritis  better?

      It seems to be a difficult balance and I’m trying to understand this before figuring this out with the rheumatologist.

      Thank you.


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          I have psoriasis and PSA which is fully in remission.

          I took low dose methotrexate before melanoma, which was 1a or insitu, depending on which pathologist you choose to believe.

          I also have a narrow band UVB light box which I use once a week, before melanoma I used it twice a week.  I have been able to scale the treatment down with no impact on the control of my psoriasis.

          After consulting with a Stanford dermatologist and one at UCSF, I am convinced these treatments did not cause the melanoma.  My dermatologist concurs, and I have continued the treatment post my one experience with melanoma, which was five years ago.

          In my experience, some doctor’s overreact and say you should not use methotrexate, light or biologics to treat your psoriasis and PSA, if you have had melanoma.

          However, they are also serious diseases and can cause severe damage and ruin your quality of life.  Educate yourself and make your own decision,  I consulted doctors outside my main insurance because I was concerned they might limit my treatment no matter what my decision.

          Your decision depends on a lot of things the severity of your melanoma, psoriasis and PSA,  If you have control over the psoriasis and PSA.    I personally have chosen to continue to treat without too much concern that these treatments cause melanoma.  Most studies on narrow band UVB and methotrexate indicate they do not increase your risk.  Read, educate yourself, consult outside experts and make your own treatment decision.

          My dermatologists were much more helpful than my rheumatologist.

          I hope this helps.



            This is just what I was looking for. Thank you, slholmdahl. I appreciate it.
              Interesting thread. I also have Psoriasis and was diagnosed with Melanoma on the thigh *Stage IIIa” at the end of 2018.

              There are various studies, which compare psoriasis patients to healthy control groups and they state that :

              a) Other types of skin cancer tend to be more frequent among the Psoriasis group, but melanoma is much less frequent in the psoriasis group compared to healthy the control group – THAT IS GOOD NEWS

              b) There is an Italian study ,which is digging into the hypothesis of a previous study that Psoriasis vulgaris might have a protective role in preventing Melanoma from becoming systemic.

              Psoriasis in melanoma patients: a prospective pilot study – PubMed (

              Here just one link, but if you google more comes up.

              Hope this helps.

              Take care


                Thanks, Christian. I appreciate the link. I will check that out.
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