LDH question- curious to hear thoughts
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

LDH question- curious to hear thoughts

› Forums › General Melanoma Community › LDH question- curious to hear thoughts

  • Post
    • March 19, 2016 at 6:11 pm
    jenny22
    Participant

    Hi,

    I've seen many posts on LDH, and know its not considered a  reliable "marker", and can fluctuate for many reasons other than  diesase progression….

    I had lab tests done last Tuesday, normal, just routine, while at NYU….they are then sent to me via their patient portal….this morning when I recived them I was shocked to see my LDH jumped amost 240 pts …..

    One thing to note, is that the NYUs lab range  for normal is 313-618….mine has stayed anywhere from 429-472 over the last year and a half….Febraury 16 th, the last one was 459…..and apparently it is now 695…… almost 240 pts higher than last month or EVER !!!!!

    I know Dr. Pavlick is not going to be too concerned as she doesn't think its a necesssary test in the absence of metatstatic disease….BUT I must say, It certainly scared me this morning.

    Just curious of others thoughts or experience on this.

    TKS,

    jenny

     

     

     

Viewing 5 reply threads
  • Replies
      • March 19, 2016 at 9:18 pm
      ed williams
      Participant

      Hi Jenny, if you go back on the forum you will find others have talked about this topic several times over the last couple of years. Best wishes!!!! Ed

      • March 19, 2016 at 9:18 pm
      ed williams
      Participant

      Hi Jenny, if you go back on the forum you will find others have talked about this topic several times over the last couple of years. Best wishes!!!! Ed

      • March 19, 2016 at 9:18 pm
      ed williams
      Participant

      Hi Jenny, if you go back on the forum you will find others have talked about this topic several times over the last couple of years. Best wishes!!!! Ed

        • March 20, 2016 at 3:09 pm
        jenny22
        Participant

        Thanks Ed and Mat-

        I did so some searching…lots here for sure….

        I wondered if post radiation changes could be "the culprit" to cause elevated LDH…i am having some delayed side effects now, though it ended Jan 12th. so hoping that may be the cause.

        I am sure it will lbe repeated next month and hopefully will go down again…and will be no further cause for concern.

        Thank you both for your responses,

         

        best,

        jenny

        • March 20, 2016 at 3:09 pm
        jenny22
        Participant

        Thanks Ed and Mat-

        I did so some searching…lots here for sure….

        I wondered if post radiation changes could be "the culprit" to cause elevated LDH…i am having some delayed side effects now, though it ended Jan 12th. so hoping that may be the cause.

        I am sure it will lbe repeated next month and hopefully will go down again…and will be no further cause for concern.

        Thank you both for your responses,

         

        best,

        jenny

        • March 20, 2016 at 3:09 pm
        jenny22
        Participant

        Thanks Ed and Mat-

        I did so some searching…lots here for sure….

        I wondered if post radiation changes could be "the culprit" to cause elevated LDH…i am having some delayed side effects now, though it ended Jan 12th. so hoping that may be the cause.

        I am sure it will lbe repeated next month and hopefully will go down again…and will be no further cause for concern.

        Thank you both for your responses,

         

        best,

        jenny

      • March 19, 2016 at 11:33 pm
      Mat
      Participant

      LDH can be a marker for progression in untreated patients.  It is a less reliable marker for folks on treatment.  LDH can rise due to inflammation, which is a common side effect of the checkpoint inhibitors, eg, all of the disorders ending in "is" like colitis.  Agree with Ed–many prior posts on this.

      • March 19, 2016 at 11:33 pm
      Mat
      Participant

      LDH can be a marker for progression in untreated patients.  It is a less reliable marker for folks on treatment.  LDH can rise due to inflammation, which is a common side effect of the checkpoint inhibitors, eg, all of the disorders ending in "is" like colitis.  Agree with Ed–many prior posts on this.

      • March 19, 2016 at 11:33 pm
      Mat
      Participant

      LDH can be a marker for progression in untreated patients.  It is a less reliable marker for folks on treatment.  LDH can rise due to inflammation, which is a common side effect of the checkpoint inhibitors, eg, all of the disorders ending in "is" like colitis.  Agree with Ed–many prior posts on this.

Viewing 5 reply threads
  • You must be logged in to reply to this topic.
About the MRF Patient Forum

The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.