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LDH question- curious to hear thoughts
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LDH question- curious to hear thoughts

› Forums › General Melanoma Community › LDH question- curious to hear thoughts

  • Post
    • March 19, 2016 at 6:11 pm
    jenny22
    Participant

      Hi,

      I've seen many posts on LDH, and know its not considered a  reliable "marker", and can fluctuate for many reasons other than  diesase progression….

      I had lab tests done last Tuesday, normal, just routine, while at NYU….they are then sent to me via their patient portal….this morning when I recived them I was shocked to see my LDH jumped amost 240 pts …..

      One thing to note, is that the NYUs lab range  for normal is 313-618….mine has stayed anywhere from 429-472 over the last year and a half….Febraury 16 th, the last one was 459…..and apparently it is now 695…… almost 240 pts higher than last month or EVER !!!!!

      I know Dr. Pavlick is not going to be too concerned as she doesn't think its a necesssary test in the absence of metatstatic disease….BUT I must say, It certainly scared me this morning.

      Just curious of others thoughts or experience on this.

      TKS,

      jenny

       

       

       

    Viewing 5 reply threads
    • Replies
        • March 19, 2016 at 9:18 pm
        ed williams
        Participant

          Hi Jenny, if you go back on the forum you will find others have talked about this topic several times over the last couple of years. Best wishes!!!! Ed

            • March 20, 2016 at 3:09 pm
            jenny22
            Participant

              Thanks Ed and Mat-

              I did so some searching…lots here for sure….

              I wondered if post radiation changes could be "the culprit" to cause elevated LDH…i am having some delayed side effects now, though it ended Jan 12th. so hoping that may be the cause.

              I am sure it will lbe repeated next month and hopefully will go down again…and will be no further cause for concern.

              Thank you both for your responses,

               

              best,

              jenny

              • March 20, 2016 at 3:09 pm
              jenny22
              Participant

                Thanks Ed and Mat-

                I did so some searching…lots here for sure….

                I wondered if post radiation changes could be "the culprit" to cause elevated LDH…i am having some delayed side effects now, though it ended Jan 12th. so hoping that may be the cause.

                I am sure it will lbe repeated next month and hopefully will go down again…and will be no further cause for concern.

                Thank you both for your responses,

                 

                best,

                jenny

                • March 20, 2016 at 3:09 pm
                jenny22
                Participant

                  Thanks Ed and Mat-

                  I did so some searching…lots here for sure….

                  I wondered if post radiation changes could be "the culprit" to cause elevated LDH…i am having some delayed side effects now, though it ended Jan 12th. so hoping that may be the cause.

                  I am sure it will lbe repeated next month and hopefully will go down again…and will be no further cause for concern.

                  Thank you both for your responses,

                   

                  best,

                  jenny

                • March 19, 2016 at 9:18 pm
                ed williams
                Participant

                  Hi Jenny, if you go back on the forum you will find others have talked about this topic several times over the last couple of years. Best wishes!!!! Ed

                  • March 19, 2016 at 9:18 pm
                  ed williams
                  Participant

                    Hi Jenny, if you go back on the forum you will find others have talked about this topic several times over the last couple of years. Best wishes!!!! Ed

                    • March 19, 2016 at 11:33 pm
                    Mat
                    Participant

                      LDH can be a marker for progression in untreated patients.  It is a less reliable marker for folks on treatment.  LDH can rise due to inflammation, which is a common side effect of the checkpoint inhibitors, eg, all of the disorders ending in "is" like colitis.  Agree with Ed–many prior posts on this.

                      • March 19, 2016 at 11:33 pm
                      Mat
                      Participant

                        LDH can be a marker for progression in untreated patients.  It is a less reliable marker for folks on treatment.  LDH can rise due to inflammation, which is a common side effect of the checkpoint inhibitors, eg, all of the disorders ending in "is" like colitis.  Agree with Ed–many prior posts on this.

                        • March 19, 2016 at 11:33 pm
                        Mat
                        Participant

                          LDH can be a marker for progression in untreated patients.  It is a less reliable marker for folks on treatment.  LDH can rise due to inflammation, which is a common side effect of the checkpoint inhibitors, eg, all of the disorders ending in "is" like colitis.  Agree with Ed–many prior posts on this.

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