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Immuno Article
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Immuno Article

› Forums › General Melanoma Community › Immuno Article

  • This topic has 6 replies, 2 voices, and was last updated 8 years ago by Mat.
  • Post
    • April 7, 2016 at 6:53 pm
    khubes
    Participant

      Hey all, I came across this article and thought I would share. http://www.onclive.com/web-exclusives/expert-always-use-frontline-immunotherapy-in-melanoma-care/1

       I know Mat mentioned looking for response rates for people on the combo after failing pembro – it looks like Dr. Luke is going to be running a trial looking into this, as he is quoted saying, "I am going to launch a clinical trial in which we are going to treat patients who received PD-1 as a single agent who progress with the combination of pembrolizumab plus ipilimumab at a low dose. We want to determine if the combination is just as good in second-line as first-line, because then we can avoid exposing the patients to the side effects until we know that they need them." 

      We may have to wait a bit longer to get this data but at least it's on their radar!  

      Best,

      Katie 

    Viewing 5 reply threads
    • Replies
        • April 9, 2016 at 2:15 am
        Maria C
        Participant

          Katie, thanks for sharing, and it's encouraging to hear of the many researchers tweaking the combo "formula" to optimize results without being so harsh on the body…keep the articles/information sharing coming!!

          • April 9, 2016 at 2:15 am
          Maria C
          Participant

            Katie, thanks for sharing, and it's encouraging to hear of the many researchers tweaking the combo "formula" to optimize results without being so harsh on the body…keep the articles/information sharing coming!!

            • April 9, 2016 at 2:15 am
            Maria C
            Participant

              Katie, thanks for sharing, and it's encouraging to hear of the many researchers tweaking the combo "formula" to optimize results without being so harsh on the body…keep the articles/information sharing coming!!

              • April 9, 2016 at 7:16 pm
              Mat
              Participant

                Yes, great article.  Thanks for posting.  Not that I had a real choice at the time, but I often wonder whether my time on BRAF-MEK (which saved my life) has diminished my ability to benefit from immunotherapy.

                • April 9, 2016 at 7:16 pm
                Mat
                Participant

                  Yes, great article.  Thanks for posting.  Not that I had a real choice at the time, but I often wonder whether my time on BRAF-MEK (which saved my life) has diminished my ability to benefit from immunotherapy.

                  • April 9, 2016 at 7:16 pm
                  Mat
                  Participant

                    Yes, great article.  Thanks for posting.  Not that I had a real choice at the time, but I often wonder whether my time on BRAF-MEK (which saved my life) has diminished my ability to benefit from immunotherapy.

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