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Had first Yervoy infusion on Friday/side effects
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Had first Yervoy infusion on Friday/side effects

› Forums › General Melanoma Community › Had first Yervoy infusion on Friday/side effects

  • Post
    • February 3, 2013 at 9:11 pm
    Jinx
    Participant

       

       

      I had my first Yervoy infusion on Friday (2/1) and actually had a side effect not from the Yervoy but from the Benadryl they gave me pryer to the infussion. Belive it or not I have never taken Benadryl in any form. Aside from this cancer, I really have never been one to get sick. The last time I was sick was about 15 years ago when there was a bad flu hitting.
      Anyway…I started feeling very strange and felt like I was going to pass out, but not really dizzy. It was like a hyper anxioty about something about to happen, alone with a feeling I was going to pass out. My blood pressure dropped from 120/72 to 88/65. They opended the iv and flushed my vein. It fianlly went away after about ten minutes. 
      Anyone else here have this happen? If so, did they use something other than Benadryl before the next infusion/

      The only side effect I had from the Yervoy (if it really was one) was a few back to back adrenalin head rushes later that night. I was a little bit slow to get going the next day, but have felt fine since.

      Jerry

    Viewing 11 reply threads
    • Replies
        • February 3, 2013 at 10:09 pm
        Lucassi
        Participant

          Hi Jerry,

          The same thing happened to my husband, although it was not with his first Yervoy infusion.  The infusion room nurse called the physician on call and it was decided that my husband was dehydrated.  After drinking some water he was fine and he didn't have the problem with the next infusion.  I made sure that he drank plenty of fluids prior to the infusion visit.

          Best of luck to you.

          Sigrid

          • February 3, 2013 at 10:09 pm
          Lucassi
          Participant

            Hi Jerry,

            The same thing happened to my husband, although it was not with his first Yervoy infusion.  The infusion room nurse called the physician on call and it was decided that my husband was dehydrated.  After drinking some water he was fine and he didn't have the problem with the next infusion.  I made sure that he drank plenty of fluids prior to the infusion visit.

            Best of luck to you.

            Sigrid

            • February 3, 2013 at 10:09 pm
            Lucassi
            Participant

              Hi Jerry,

              The same thing happened to my husband, although it was not with his first Yervoy infusion.  The infusion room nurse called the physician on call and it was decided that my husband was dehydrated.  After drinking some water he was fine and he didn't have the problem with the next infusion.  I made sure that he drank plenty of fluids prior to the infusion visit.

              Best of luck to you.

              Sigrid

                • February 3, 2013 at 10:54 pm
                Jinx
                Participant

                  Thank you Sigrid

                  That is good to know and a simple solution. I am sure I did not drink much water the day I went as I find it hard sometimes to drink water. I have been working at it and I will work harder now.

                  J

                  • February 3, 2013 at 10:54 pm
                  Jinx
                  Participant

                    Thank you Sigrid

                    That is good to know and a simple solution. I am sure I did not drink much water the day I went as I find it hard sometimes to drink water. I have been working at it and I will work harder now.

                    J

                    • February 3, 2013 at 10:54 pm
                    Jinx
                    Participant

                      Thank you Sigrid

                      That is good to know and a simple solution. I am sure I did not drink much water the day I went as I find it hard sometimes to drink water. I have been working at it and I will work harder now.

                      J

                    • February 4, 2013 at 12:41 am
                    awillett1991
                    Participant
                      I have had problems with dehydration from Yervoy since I finished round 2. Still having to drink plenty of extra fluids, finished 12/3/12. Not just water, but Gatorade too!!
                        • February 6, 2013 at 2:10 am
                        Marcia1
                        Participant

                          My Mom, who has Stage IV Melanoma and is 86, had her 1st Yervoy treatment Jan. 21 and she is now in the hospital with dehydration, but she has constant diarrhea and they can't seem to get it under control.  Gave her steroids so far.  I'll have to make sure she drinks lots of water prior to and during her next treatment (which she wants to have).

                          • February 6, 2013 at 2:10 am
                          Marcia1
                          Participant

                            My Mom, who has Stage IV Melanoma and is 86, had her 1st Yervoy treatment Jan. 21 and she is now in the hospital with dehydration, but she has constant diarrhea and they can't seem to get it under control.  Gave her steroids so far.  I'll have to make sure she drinks lots of water prior to and during her next treatment (which she wants to have).

                            • February 6, 2013 at 2:10 am
                            Marcia1
                            Participant

                              My Mom, who has Stage IV Melanoma and is 86, had her 1st Yervoy treatment Jan. 21 and she is now in the hospital with dehydration, but she has constant diarrhea and they can't seem to get it under control.  Gave her steroids so far.  I'll have to make sure she drinks lots of water prior to and during her next treatment (which she wants to have).

                            • February 4, 2013 at 12:41 am
                            awillett1991
                            Participant
                              I have had problems with dehydration from Yervoy since I finished round 2. Still having to drink plenty of extra fluids, finished 12/3/12. Not just water, but Gatorade too!!
                              • February 4, 2013 at 12:41 am
                              awillett1991
                              Participant
                                I have had problems with dehydration from Yervoy since I finished round 2. Still having to drink plenty of extra fluids, finished 12/3/12. Not just water, but Gatorade too!!
                                • February 6, 2013 at 4:28 pm
                                Gene_S
                                Participant

                                  My husband never had Benadryl administered before his Ipi infusions and still doesn't.  Maybe next time they will just try the Ipi and forgo anything else.

                                  Judy (loving wife of Gene Stage IV on Ipi since March 2011 and NED)

                                  • February 6, 2013 at 4:28 pm
                                  Gene_S
                                  Participant

                                    My husband never had Benadryl administered before his Ipi infusions and still doesn't.  Maybe next time they will just try the Ipi and forgo anything else.

                                    Judy (loving wife of Gene Stage IV on Ipi since March 2011 and NED)

                                      • February 7, 2013 at 5:39 am
                                      kylez
                                      Participant

                                        Judy, I can't recall being asked to take any pills before any of the Ipi infusions either.

                                        • February 7, 2013 at 5:39 am
                                        kylez
                                        Participant

                                          Judy, I can't recall being asked to take any pills before any of the Ipi infusions either.

                                          • February 7, 2013 at 5:39 am
                                          kylez
                                          Participant

                                            Judy, I can't recall being asked to take any pills before any of the Ipi infusions either.

                                          • February 6, 2013 at 4:28 pm
                                          Gene_S
                                          Participant

                                            My husband never had Benadryl administered before his Ipi infusions and still doesn't.  Maybe next time they will just try the Ipi and forgo anything else.

                                            Judy (loving wife of Gene Stage IV on Ipi since March 2011 and NED)

                                            • February 8, 2013 at 4:52 pm
                                            fishook40
                                            Participant

                                               

                                              Hi, I’m into my second week after the first IV treatment of the Yervoy. So far no problems, I feel great and the dog and I walked about 3 miles today. Now to your question about the Benadryl. I started on interferon the second of Jan. in 2011. After they started the IV , my legs would jump all over the place, I had trouble staying in the chair. I complained and they removed the Benadryl, and everything was better, no jerks or spasms . Last week when I started the IV of the Yervoy I told my doctor , no Benadryl, at first she said they would cut it in half, and was adamant that I wanted no, none of the Benadryl. So they left it out and gave me Tylenol half way through the treatment and I never had any problems. Jerre
                                              • February 8, 2013 at 4:52 pm
                                              fishook40
                                              Participant

                                                 

                                                Hi, I’m into my second week after the first IV treatment of the Yervoy. So far no problems, I feel great and the dog and I walked about 3 miles today. Now to your question about the Benadryl. I started on interferon the second of Jan. in 2011. After they started the IV , my legs would jump all over the place, I had trouble staying in the chair. I complained and they removed the Benadryl, and everything was better, no jerks or spasms . Last week when I started the IV of the Yervoy I told my doctor , no Benadryl, at first she said they would cut it in half, and was adamant that I wanted no, none of the Benadryl. So they left it out and gave me Tylenol half way through the treatment and I never had any problems. Jerre
                                                • February 8, 2013 at 4:52 pm
                                                fishook40
                                                Participant

                                                   

                                                  Hi, I’m into my second week after the first IV treatment of the Yervoy. So far no problems, I feel great and the dog and I walked about 3 miles today. Now to your question about the Benadryl. I started on interferon the second of Jan. in 2011. After they started the IV , my legs would jump all over the place, I had trouble staying in the chair. I complained and they removed the Benadryl, and everything was better, no jerks or spasms . Last week when I started the IV of the Yervoy I told my doctor , no Benadryl, at first she said they would cut it in half, and was adamant that I wanted no, none of the Benadryl. So they left it out and gave me Tylenol half way through the treatment and I never had any problems. Jerre
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