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?? for anyone on a Merck PD1 trial, please
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?? for anyone on a Merck PD1 trial, please

› Forums › General Melanoma Community › ?? for anyone on a Merck PD1 trial, please

  • Post
    • June 13, 2013 at 6:24 pm
    NYKaren
    Participant
      Hello,
      If you are on a Merck PD1 trial and had to do a 28-day washout from another drug (in my case, Zelboraf), did you have to wait to have your scans until the 28 days were up, or were you able to have the scans the week before and then actually begin the trial on day 29 or 30?

      It looks like I'll be on the Phase 2 trial (with the chemo arm, urggh), provided of course my brain MRI is clean, and I'm trying to see how fast I can actually start whichever drug I get. My onc has me scheduled for scans on day 29, but she's asking Merck if the scans can be done the week before, so I thought I'd ask you'all here.
      Thankfully, she prescribed Ativan, as I am a real mess with the waiting.  It's back in my ear, and quite painful. 
      Thanks,
      Karen 

    Viewing 11 reply threads
    • Replies
        • June 13, 2013 at 9:05 pm
        awillett1991
        Participant
          Karen – I messaged you details but I started exactly 28 days after my last Zelboraf. It’s possible! Hang in there!!

          Amy

          • June 13, 2013 at 9:05 pm
          awillett1991
          Participant
            Karen – I messaged you details but I started exactly 28 days after my last Zelboraf. It’s possible! Hang in there!!

            Amy

            • June 13, 2013 at 9:05 pm
            awillett1991
            Participant
              Karen – I messaged you details but I started exactly 28 days after my last Zelboraf. It’s possible! Hang in there!!

              Amy

              • June 15, 2013 at 5:25 pm
              tasjacques
              Participant
                Hi Karen,
                My husband’s trial is Phase 1 anti PD1.
                First set of CT scans before IPi was on 2-27, started ipi on 3-7, second and last ipi on 3-27 … repeated CT scans for trial on May 10. Started PD1 on June 7.
                Hope this time line helps you a bit. The waiting time for scans to be done, and be read by trial radiologist is uneasy and super hard … You want answer yesterday at least I did !!! My husband kept telling patience is a virtue. Well my patience was tested very second 🙂
                I pray for your MRI TO be clean! And you get the necessary help.
                Take care,
                Elenise
                • June 15, 2013 at 5:25 pm
                tasjacques
                Participant
                  Hi Karen,
                  My husband’s trial is Phase 1 anti PD1.
                  First set of CT scans before IPi was on 2-27, started ipi on 3-7, second and last ipi on 3-27 … repeated CT scans for trial on May 10. Started PD1 on June 7.
                  Hope this time line helps you a bit. The waiting time for scans to be done, and be read by trial radiologist is uneasy and super hard … You want answer yesterday at least I did !!! My husband kept telling patience is a virtue. Well my patience was tested very second 🙂
                  I pray for your MRI TO be clean! And you get the necessary help.
                  Take care,
                  Elenise
                  • June 15, 2013 at 5:25 pm
                  tasjacques
                  Participant
                    Hi Karen,
                    My husband’s trial is Phase 1 anti PD1.
                    First set of CT scans before IPi was on 2-27, started ipi on 3-7, second and last ipi on 3-27 … repeated CT scans for trial on May 10. Started PD1 on June 7.
                    Hope this time line helps you a bit. The waiting time for scans to be done, and be read by trial radiologist is uneasy and super hard … You want answer yesterday at least I did !!! My husband kept telling patience is a virtue. Well my patience was tested very second 🙂
                    I pray for your MRI TO be clean! And you get the necessary help.
                    Take care,
                    Elenise
                    • June 19, 2013 at 12:47 am
                    5374brian
                    Participant

                      Keep pushing and praying. My wife was all good on her scans and MRI but her hemogloban was low. Our oncologist had discussions for a few days with the clinical trial investagator and we could not get in. As of yesterday we are now hopefully approved for the BMS trial. We were due for a call today but did not get it. My wife finished her IPI and has not had a good response so our oncologist is pushing for the PD-1 trials. Since Dec 07 when she was diagnosed we have noticed when 1 door closes another 1 opens. Good luck… My wife is a patient at Moffitt in Fl. 

                      • June 19, 2013 at 12:47 am
                      5374brian
                      Participant

                        Keep pushing and praying. My wife was all good on her scans and MRI but her hemogloban was low. Our oncologist had discussions for a few days with the clinical trial investagator and we could not get in. As of yesterday we are now hopefully approved for the BMS trial. We were due for a call today but did not get it. My wife finished her IPI and has not had a good response so our oncologist is pushing for the PD-1 trials. Since Dec 07 when she was diagnosed we have noticed when 1 door closes another 1 opens. Good luck… My wife is a patient at Moffitt in Fl. 

                        • June 19, 2013 at 12:47 am
                        5374brian
                        Participant

                          Keep pushing and praying. My wife was all good on her scans and MRI but her hemogloban was low. Our oncologist had discussions for a few days with the clinical trial investagator and we could not get in. As of yesterday we are now hopefully approved for the BMS trial. We were due for a call today but did not get it. My wife finished her IPI and has not had a good response so our oncologist is pushing for the PD-1 trials. Since Dec 07 when she was diagnosed we have noticed when 1 door closes another 1 opens. Good luck… My wife is a patient at Moffitt in Fl. 

                          • June 20, 2013 at 2:01 am
                          aldakota22
                          Participant

                            Karen, So sorry that you are having to wait what seems like an eternity.Will keep you in my prayers for a complete response once you are in the PD1 trial. Beat the Beast.   Al

                            • June 20, 2013 at 2:01 am
                            aldakota22
                            Participant

                              Karen, So sorry that you are having to wait what seems like an eternity.Will keep you in my prayers for a complete response once you are in the PD1 trial. Beat the Beast.   Al

                              • June 20, 2013 at 2:01 am
                              aldakota22
                              Participant

                                Karen, So sorry that you are having to wait what seems like an eternity.Will keep you in my prayers for a complete response once you are in the PD1 trial. Beat the Beast.   Al

                                • June 20, 2013 at 1:52 pm
                                Snickers60
                                Participant

                                  Waiting on anything pertaining to Melanoma is hard.   Hang in there, Karen !   You're getting there.   We will be interested to follow you on the PD-1. 

                                  Nancy (devoted wife of 3X Warrior Wayne) 

                                  • June 20, 2013 at 1:52 pm
                                  Snickers60
                                  Participant

                                    Waiting on anything pertaining to Melanoma is hard.   Hang in there, Karen !   You're getting there.   We will be interested to follow you on the PD-1. 

                                    Nancy (devoted wife of 3X Warrior Wayne) 

                                    • June 20, 2013 at 1:52 pm
                                    Snickers60
                                    Participant

                                      Waiting on anything pertaining to Melanoma is hard.   Hang in there, Karen !   You're getting there.   We will be interested to follow you on the PD-1. 

                                      Nancy (devoted wife of 3X Warrior Wayne) 

                                  Viewing 11 reply threads
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