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Dabrafenib is working!!
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Dabrafenib is working!!

› Forums › General Melanoma Community › Dabrafenib is working!!

  • Post
    • November 21, 2013 at 8:21 pm
    awillett1991
    Participant

      After cardiac surgery in Sept I went on Dabrafenib. Then added Mekinist. I could not tolerate the Mekinist so I went back to just Dabrafenib.  Been on it 8 wks .  

      Today my onc said it was so clear I was responding and he was thrilled. I even have a patch of vitiligo which he said they have seen with dabrafenib or could be the Ipi I finished a year ago or a combo of dab and the anti pd1 doses I had, who knows? Anyway, just thrilled and thankful to God!

      Amy

    Viewing 17 reply threads
    • Replies
        • November 21, 2013 at 9:31 pm
        killmel
        Participant

          Amy,

           

          I am so happy for you. Have you had scans that show shrinking tumors or tumors that are gone?

          God Bless

            • November 22, 2013 at 2:29 am
            awillett1991
            Participant

              My scans show stable tumors in heart and brain. LDH has dropped from 300s to 101 and the rest of my bloodwork was very good. 

              • November 22, 2013 at 2:29 am
              awillett1991
              Participant

                My scans show stable tumors in heart and brain. LDH has dropped from 300s to 101 and the rest of my bloodwork was very good. 

                • November 22, 2013 at 2:29 am
                awillett1991
                Participant

                  My scans show stable tumors in heart and brain. LDH has dropped from 300s to 101 and the rest of my bloodwork was very good. 

                • November 21, 2013 at 9:31 pm
                killmel
                Participant

                  Amy,

                   

                  I am so happy for you. Have you had scans that show shrinking tumors or tumors that are gone?

                  God Bless

                  • November 21, 2013 at 9:31 pm
                  killmel
                  Participant

                    Amy,

                     

                    I am so happy for you. Have you had scans that show shrinking tumors or tumors that are gone?

                    God Bless

                    • November 22, 2013 at 12:04 am
                    cep3700
                    Participant

                      So happy for you!!!! Such great news! Your strength is amazing, Congrats!

                        • November 22, 2013 at 12:55 am
                        Maureen038
                        Participant

                          That's such wonderful news Amy!!

                          maureen

                          • November 22, 2013 at 12:55 am
                          Maureen038
                          Participant

                            That's such wonderful news Amy!!

                            maureen

                            • November 22, 2013 at 12:55 am
                            Maureen038
                            Participant

                              That's such wonderful news Amy!!

                              maureen

                            • November 22, 2013 at 12:04 am
                            cep3700
                            Participant

                              So happy for you!!!! Such great news! Your strength is amazing, Congrats!

                              • November 22, 2013 at 12:04 am
                              cep3700
                              Participant

                                So happy for you!!!! Such great news! Your strength is amazing, Congrats!

                                • November 22, 2013 at 3:05 am
                                POW
                                Participant

                                  That's absoutely fantastic news, Amy! Good for you! I was disappointed when you had to get off the MEK but it looks like you're responding just fine to the dabrafenib alone, which some people do. Keep eating healthfully and get a little exercise and maybe your immune system will now be able to kick mel's butt!

                                  • November 22, 2013 at 3:05 am
                                  POW
                                  Participant

                                    That's absoutely fantastic news, Amy! Good for you! I was disappointed when you had to get off the MEK but it looks like you're responding just fine to the dabrafenib alone, which some people do. Keep eating healthfully and get a little exercise and maybe your immune system will now be able to kick mel's butt!

                                    • November 22, 2013 at 3:05 am
                                    POW
                                    Participant

                                      That's absoutely fantastic news, Amy! Good for you! I was disappointed when you had to get off the MEK but it looks like you're responding just fine to the dabrafenib alone, which some people do. Keep eating healthfully and get a little exercise and maybe your immune system will now be able to kick mel's butt!

                                      • November 22, 2013 at 3:43 am
                                      BrianP
                                      Participant

                                        That's awesome Amy!

                                        So let me get this straight.  You have Mek, Dab, Ipi, and pd1 swimming around that blood of yours.  No wonder that melanoma is crying uncle!  Nice work.

                                        Brian

                                        • November 22, 2013 at 3:43 am
                                        BrianP
                                        Participant

                                          That's awesome Amy!

                                          So let me get this straight.  You have Mek, Dab, Ipi, and pd1 swimming around that blood of yours.  No wonder that melanoma is crying uncle!  Nice work.

                                          Brian

                                          • November 22, 2013 at 3:43 am
                                          BrianP
                                          Participant

                                            That's awesome Amy!

                                            So let me get this straight.  You have Mek, Dab, Ipi, and pd1 swimming around that blood of yours.  No wonder that melanoma is crying uncle!  Nice work.

                                            Brian

                                            • November 22, 2013 at 6:27 am
                                            tasjacques
                                            Participant

                                              Amy so happy for you!!! You go girl!!! So many treatments and to see somethin working is great. The vitiligo is something that happens with PD 1 (My husband has it as a respond to PD 1), I don't know if the other treatments also has that side effect …. but it does not matter which one is causing it as long as YOU ARE RESPONDING YEY

                                              Elenise

                                                • November 22, 2013 at 3:34 pm
                                                NYKaren
                                                Participant

                                                  AMY, I am so thrilled for you! 

                                                  That's our motto—never give up!

                                                  Just out of curiousity (because I'll hopefully be on it too soon), how bad and what were the side effects of the Menkinist?

                                                  xoxo,

                                                  Karen

                                                  • November 22, 2013 at 3:34 pm
                                                  NYKaren
                                                  Participant

                                                    AMY, I am so thrilled for you! 

                                                    That's our motto—never give up!

                                                    Just out of curiousity (because I'll hopefully be on it too soon), how bad and what were the side effects of the Menkinist?

                                                    xoxo,

                                                    Karen

                                                    • November 22, 2013 at 3:34 pm
                                                    NYKaren
                                                    Participant

                                                      AMY, I am so thrilled for you! 

                                                      That's our motto—never give up!

                                                      Just out of curiousity (because I'll hopefully be on it too soon), how bad and what were the side effects of the Menkinist?

                                                      xoxo,

                                                      Karen

                                                      • November 22, 2013 at 11:15 pm
                                                      awillett1991
                                                      Participant

                                                        Karen – my side effects were really bad, I was in the hospital for two days, but this is  not common. I am BRAF v600D so maybe that's why, I don't know. I had a fever of 102.8, delirium, mouth sores, wasn't eating, severe chills, anemia, and slept all the time.  It was a little scary. 

                                                        Amy

                                                        • November 22, 2013 at 11:15 pm
                                                        awillett1991
                                                        Participant

                                                          Karen – my side effects were really bad, I was in the hospital for two days, but this is  not common. I am BRAF v600D so maybe that's why, I don't know. I had a fever of 102.8, delirium, mouth sores, wasn't eating, severe chills, anemia, and slept all the time.  It was a little scary. 

                                                          Amy

                                                          • November 22, 2013 at 11:15 pm
                                                          awillett1991
                                                          Participant

                                                            Karen – my side effects were really bad, I was in the hospital for two days, but this is  not common. I am BRAF v600D so maybe that's why, I don't know. I had a fever of 102.8, delirium, mouth sores, wasn't eating, severe chills, anemia, and slept all the time.  It was a little scary. 

                                                            Amy

                                                            • November 23, 2013 at 11:00 pm
                                                            NYKaren
                                                            Participant

                                                              Thanks, Amy. Yes, that does sound bad. There's nothing quite like waking up in the hospital with no idea how you got there. 

                                                              Thinking of you,

                                                              karen

                                                              • November 23, 2013 at 11:00 pm
                                                              NYKaren
                                                              Participant

                                                                Thanks, Amy. Yes, that does sound bad. There's nothing quite like waking up in the hospital with no idea how you got there. 

                                                                Thinking of you,

                                                                karen

                                                                • November 23, 2013 at 11:00 pm
                                                                NYKaren
                                                                Participant

                                                                  Thanks, Amy. Yes, that does sound bad. There's nothing quite like waking up in the hospital with no idea how you got there. 

                                                                  Thinking of you,

                                                                  karen

                                                                • November 22, 2013 at 6:27 am
                                                                tasjacques
                                                                Participant

                                                                  Amy so happy for you!!! You go girl!!! So many treatments and to see somethin working is great. The vitiligo is something that happens with PD 1 (My husband has it as a respond to PD 1), I don't know if the other treatments also has that side effect …. but it does not matter which one is causing it as long as YOU ARE RESPONDING YEY

                                                                  Elenise

                                                                  • November 22, 2013 at 6:27 am
                                                                  tasjacques
                                                                  Participant

                                                                    Amy so happy for you!!! You go girl!!! So many treatments and to see somethin working is great. The vitiligo is something that happens with PD 1 (My husband has it as a respond to PD 1), I don't know if the other treatments also has that side effect …. but it does not matter which one is causing it as long as YOU ARE RESPONDING YEY

                                                                    Elenise

                                                                    • December 8, 2013 at 2:41 am
                                                                    aldakota22
                                                                    Participant

                                                                      Thank God for the good news.Keep that PMA .You will Beat the Beast.   Al

                                                                      • December 8, 2013 at 2:41 am
                                                                      aldakota22
                                                                      Participant

                                                                        Thank God for the good news.Keep that PMA .You will Beat the Beast.   Al

                                                                        • December 8, 2013 at 2:41 am
                                                                        aldakota22
                                                                        Participant

                                                                          Thank God for the good news.Keep that PMA .You will Beat the Beast.   Al

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