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Boyfriend Randy scan results 3 months since starting Merk-3475
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Boyfriend Randy scan results 3 months since starting Merk-3475

› Forums › General Melanoma Community › Boyfriend Randy scan results 3 months since starting Merk-3475

  • Post
    • May 21, 2013 at 8:00 am
    Amanda
    Participant

      Hello all, we had our every three week check and infusion today on the Merk-3475 Anti-Pd-1 trial ( 5th infusion) , scan results that we took three weeks ago were revealed.  All tumors in the body have shrunk, and the small brain met that was stable prior to treatment is still stable.  Left upper lobe lung: was 14x12mm, now 12x10mm, Anterior mediastinal was 44x26mm now 28mmx24mm.  Right upper lobe lung was 38x26mm now 32mmx22mm.  Liver segment II was 21mmx18mm now 20mmx14mm.  And ventral Peritoneal was 20mmx17mm now 18mmx14mm.  We are extatic!

      Hello all, we had our every three week check and infusion today on the Merk-3475 Anti-Pd-1 trial ( 5th infusion) , scan results that we took three weeks ago were revealed.  All tumors in the body have shrunk, and the small brain met that was stable prior to treatment is still stable.  Left upper lobe lung: was 14x12mm, now 12x10mm, Anterior mediastinal was 44x26mm now 28mmx24mm.  Right upper lobe lung was 38x26mm now 32mmx22mm.  Liver segment II was 21mmx18mm now 20mmx14mm.  And ventral Peritoneal was 20mmx17mm now 18mmx14mm.  We are extatic!  He has regained all his weight lost from his bowel obstruction, and we have gone on bike rides again…He's awake more often that i am!!! haha!  Hoping it continues for a long time!

      On a side note Dr. Ribas noted that they are opening a new arm of the trial with 200 more patients.  Will be randomized between 2mg and 10mg and every 2 weeks or every 3 weeks…at UCLA. 

      -Amanda-
      Girlfriend of Randy, stage 4 no primary.

    Viewing 5 reply threads
    • Replies
        • May 21, 2013 at 9:17 am
        aldakota22
        Participant

          Keep the good news comming.Happy that the latest scans show continued shrinkage of  all tumors.Thank God. Beat the Beast.  Al

          • May 21, 2013 at 9:17 am
          aldakota22
          Participant

            Keep the good news comming.Happy that the latest scans show continued shrinkage of  all tumors.Thank God. Beat the Beast.  Al

            • May 21, 2013 at 9:17 am
            aldakota22
            Participant

              Keep the good news comming.Happy that the latest scans show continued shrinkage of  all tumors.Thank God. Beat the Beast.  Al

              • May 21, 2013 at 1:12 pm
              awillett1991
              Participant
                Congrats and thanks for posting your good news. How far in do you think he was when he started to feel better? I’m due for infusion #2 Next week and I have to admit every time I think of these scans at 12 wks (16 really, with the process of getting into the trial) I keep thinking that is WAY too long to go. I guess if it isn’t working I’ll know though before then.

                Thanks, Amy

                  • May 23, 2013 at 1:20 am
                  Amanda
                  Participant

                    I would say Randy started feeling better pretty much right away.  He hasn't had the fatigue that is a noted side effect, but rather MORE energy.  His tumors that we could feel stabalized right away it seemed like, and then by infusion 2, or a couple weeks after literally over night they had visibly started shrinking, And have been shrinking ever since.  two or three small tumors we felt before are gone, and the huge tumor on his pectoral that was the size of a softball is now a little bigger than a golf ball.  As well as all tumors inside are shrinking.  If you have any more questions i'd be glad to anwer as best i can.  Good luck with your treatment and i hope you post soon that you're responding as well!!

                    -Amanda-

                    • May 23, 2013 at 1:20 am
                    Amanda
                    Participant

                      I would say Randy started feeling better pretty much right away.  He hasn't had the fatigue that is a noted side effect, but rather MORE energy.  His tumors that we could feel stabalized right away it seemed like, and then by infusion 2, or a couple weeks after literally over night they had visibly started shrinking, And have been shrinking ever since.  two or three small tumors we felt before are gone, and the huge tumor on his pectoral that was the size of a softball is now a little bigger than a golf ball.  As well as all tumors inside are shrinking.  If you have any more questions i'd be glad to anwer as best i can.  Good luck with your treatment and i hope you post soon that you're responding as well!!

                      -Amanda-

                      • May 23, 2013 at 1:20 am
                      Amanda
                      Participant

                        I would say Randy started feeling better pretty much right away.  He hasn't had the fatigue that is a noted side effect, but rather MORE energy.  His tumors that we could feel stabalized right away it seemed like, and then by infusion 2, or a couple weeks after literally over night they had visibly started shrinking, And have been shrinking ever since.  two or three small tumors we felt before are gone, and the huge tumor on his pectoral that was the size of a softball is now a little bigger than a golf ball.  As well as all tumors inside are shrinking.  If you have any more questions i'd be glad to anwer as best i can.  Good luck with your treatment and i hope you post soon that you're responding as well!!

                        -Amanda-

                      • May 21, 2013 at 1:12 pm
                      awillett1991
                      Participant
                        Congrats and thanks for posting your good news. How far in do you think he was when he started to feel better? I’m due for infusion #2 Next week and I have to admit every time I think of these scans at 12 wks (16 really, with the process of getting into the trial) I keep thinking that is WAY too long to go. I guess if it isn’t working I’ll know though before then.

                        Thanks, Amy

                        • May 21, 2013 at 1:12 pm
                        awillett1991
                        Participant
                          Congrats and thanks for posting your good news. How far in do you think he was when he started to feel better? I’m due for infusion #2 Next week and I have to admit every time I think of these scans at 12 wks (16 really, with the process of getting into the trial) I keep thinking that is WAY too long to go. I guess if it isn’t working I’ll know though before then.

                          Thanks, Amy

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