› Forums › General Melanoma Community › 5 year Anniversary
- This topic has 51 replies, 13 voices, and was last updated 8 years, 11 months ago by
Scooby123.
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- March 4, 2016 at 3:04 pm
5 years ago my husband who had just became Stage IV started the Clinical Trial of (IPI) Yervoy 10mg/kg and GM-CSF. We had the 5 year appointment yesterday with the oncologist and he has been NED for almost 3 1/2 years.
There were 12 or 13 people in this Trial at University Hospital in Cleveland, OH and 4 of them are doing good still.
If you would like to read about his journey with melanoma and the trial you can check out his profile.
Judy loving wife of Gene Stage IV and now NED
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- March 4, 2016 at 3:54 pm
Thanks for sharing Judy. Congrats.
Doesn't appear as though the GM-CSF had that much added benefit to Ipi alone. Is that your takeaway as well?
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- March 4, 2016 at 8:31 pm
The GM-CSF really helps build the immune system and has been used for over 25 years for some other cancers and this was I believe the first time the used it in conjunction with Ipi for Melanoma. Also Ipi became Yervoy and was approved by the FDA on March 26, 2011 at the 3 mg/kg so in my opinion they were pushing for the Ipi alone because this they hadn't figured out if it would help and then they had so many other new drugs they were doing trials on. He started his trial on March 3 just before FDA approved it.
Judy
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- March 4, 2016 at 8:31 pm
The GM-CSF really helps build the immune system and has been used for over 25 years for some other cancers and this was I believe the first time the used it in conjunction with Ipi for Melanoma. Also Ipi became Yervoy and was approved by the FDA on March 26, 2011 at the 3 mg/kg so in my opinion they were pushing for the Ipi alone because this they hadn't figured out if it would help and then they had so many other new drugs they were doing trials on. He started his trial on March 3 just before FDA approved it.
Judy
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- March 4, 2016 at 8:31 pm
The GM-CSF really helps build the immune system and has been used for over 25 years for some other cancers and this was I believe the first time the used it in conjunction with Ipi for Melanoma. Also Ipi became Yervoy and was approved by the FDA on March 26, 2011 at the 3 mg/kg so in my opinion they were pushing for the Ipi alone because this they hadn't figured out if it would help and then they had so many other new drugs they were doing trials on. He started his trial on March 3 just before FDA approved it.
Judy
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- March 5, 2016 at 8:52 pm
Thanks Judy. Hope my question didn't offend. Just for my own knowledge I was curious if the investigators thought the GM-CSF helped. I think if you treated 12 or 13 stage IVers with Ipi alone you'd probably also have pretty close to 4 still doing well.
Brian
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- March 5, 2016 at 8:52 pm
Thanks Judy. Hope my question didn't offend. Just for my own knowledge I was curious if the investigators thought the GM-CSF helped. I think if you treated 12 or 13 stage IVers with Ipi alone you'd probably also have pretty close to 4 still doing well.
Brian
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- March 5, 2016 at 8:52 pm
Thanks Judy. Hope my question didn't offend. Just for my own knowledge I was curious if the investigators thought the GM-CSF helped. I think if you treated 12 or 13 stage IVers with Ipi alone you'd probably also have pretty close to 4 still doing well.
Brian
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- March 4, 2016 at 6:10 pm
Congrats Gene and Judy! Great news!!!
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- March 4, 2016 at 6:10 pm
Congrats Gene and Judy! Great news!!!
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- March 4, 2016 at 6:10 pm
Congrats Gene and Judy! Great news!!!
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- March 4, 2016 at 8:00 pm
Congratulations to the both of you. Wonderful news!
Gwen
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- March 4, 2016 at 8:00 pm
Congratulations to the both of you. Wonderful news!
Gwen
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- March 4, 2016 at 8:00 pm
Congratulations to the both of you. Wonderful news!
Gwen
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- March 5, 2016 at 1:45 am
What a wonderful post! So happy for you both! Thank you for sharing!
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- March 5, 2016 at 1:45 am
What a wonderful post! So happy for you both! Thank you for sharing!
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- March 5, 2016 at 1:45 am
What a wonderful post! So happy for you both! Thank you for sharing!
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- March 5, 2016 at 1:49 am
Great news, thanks for sharing!
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- March 5, 2016 at 1:49 am
Great news, thanks for sharing!
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- March 5, 2016 at 1:49 am
Great news, thanks for sharing!
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- March 6, 2016 at 1:29 pm
Congratulations Gene and Judy!! I'm always interested in your posts and progress as our stories are very similar in many ways. I started the same trial shortly after becoming stage 4 in May of 11' I believe about 2 months after you did (I was ipi only arm). I too have been NED for 3.5 years. I will hopefully reach the 5 year milestone this May. Congratulations again – we are so blessed to be ipi responders!
Tom
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- March 6, 2016 at 1:29 pm
Congratulations Gene and Judy!! I'm always interested in your posts and progress as our stories are very similar in many ways. I started the same trial shortly after becoming stage 4 in May of 11' I believe about 2 months after you did (I was ipi only arm). I too have been NED for 3.5 years. I will hopefully reach the 5 year milestone this May. Congratulations again – we are so blessed to be ipi responders!
Tom
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- March 6, 2016 at 1:29 pm
Congratulations Gene and Judy!! I'm always interested in your posts and progress as our stories are very similar in many ways. I started the same trial shortly after becoming stage 4 in May of 11' I believe about 2 months after you did (I was ipi only arm). I too have been NED for 3.5 years. I will hopefully reach the 5 year milestone this May. Congratulations again – we are so blessed to be ipi responders!
Tom
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- March 6, 2016 at 3:13 pm
Thank you all. I hope and pray all of you reach this status as well in whatever treatments you are taking. It has sure been a blessing to us especially since after Gene's NED status our daughter was diagnosed with colon cancer and cancer of the peritoneum. She fought for a year and passed last July.
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- March 6, 2016 at 9:38 pm
Oh, Judy. I'm so sorry. What trials your family has gone through…
Gwen
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- March 6, 2016 at 9:38 pm
Oh, Judy. I'm so sorry. What trials your family has gone through…
Gwen
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- March 6, 2016 at 9:38 pm
Oh, Judy. I'm so sorry. What trials your family has gone through…
Gwen
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- March 6, 2016 at 3:13 pm
Thank you all. I hope and pray all of you reach this status as well in whatever treatments you are taking. It has sure been a blessing to us especially since after Gene's NED status our daughter was diagnosed with colon cancer and cancer of the peritoneum. She fought for a year and passed last July.
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- March 6, 2016 at 3:13 pm
Thank you all. I hope and pray all of you reach this status as well in whatever treatments you are taking. It has sure been a blessing to us especially since after Gene's NED status our daughter was diagnosed with colon cancer and cancer of the peritoneum. She fought for a year and passed last July.
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- March 6, 2016 at 8:28 pm
Great news – congratulations!
Kevin
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- March 6, 2016 at 8:28 pm
Great news – congratulations!
Kevin
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- March 6, 2016 at 8:28 pm
Great news – congratulations!
Kevin
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