Dabrafenib is working!!
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Dabrafenib is working!!

› Forums › General Melanoma Community › Dabrafenib is working!!

  • Post
    • November 21, 2013 at 8:21 pm
    awillett1991
    Participant

    After cardiac surgery in Sept I went on Dabrafenib. Then added Mekinist. I could not tolerate the Mekinist so I went back to just Dabrafenib.  Been on it 8 wks .  

    Today my onc said it was so clear I was responding and he was thrilled. I even have a patch of vitiligo which he said they have seen with dabrafenib or could be the Ipi I finished a year ago or a combo of dab and the anti pd1 doses I had, who knows? Anyway, just thrilled and thankful to God!

    Amy

Viewing 17 reply threads
  • Replies
      • November 21, 2013 at 9:31 pm
      killmel
      Participant

      Amy,

       

      I am so happy for you. Have you had scans that show shrinking tumors or tumors that are gone?

      God Bless

        • November 22, 2013 at 2:29 am
        awillett1991
        Participant

        My scans show stable tumors in heart and brain. LDH has dropped from 300s to 101 and the rest of my bloodwork was very good. 

        • November 22, 2013 at 2:29 am
        awillett1991
        Participant

        My scans show stable tumors in heart and brain. LDH has dropped from 300s to 101 and the rest of my bloodwork was very good. 

        • November 22, 2013 at 2:29 am
        awillett1991
        Participant

        My scans show stable tumors in heart and brain. LDH has dropped from 300s to 101 and the rest of my bloodwork was very good. 

      • November 21, 2013 at 9:31 pm
      killmel
      Participant

      Amy,

       

      I am so happy for you. Have you had scans that show shrinking tumors or tumors that are gone?

      God Bless

      • November 21, 2013 at 9:31 pm
      killmel
      Participant

      Amy,

       

      I am so happy for you. Have you had scans that show shrinking tumors or tumors that are gone?

      God Bless

      • November 22, 2013 at 12:04 am
      cep3700
      Participant

      So happy for you!!!! Such great news! Your strength is amazing, Congrats!

        • November 22, 2013 at 12:55 am
        Maureen038
        Participant

        That's such wonderful news Amy!!

        maureen

        • November 22, 2013 at 12:55 am
        Maureen038
        Participant

        That's such wonderful news Amy!!

        maureen

        • November 22, 2013 at 12:55 am
        Maureen038
        Participant

        That's such wonderful news Amy!!

        maureen

      • November 22, 2013 at 12:04 am
      cep3700
      Participant

      So happy for you!!!! Such great news! Your strength is amazing, Congrats!

      • November 22, 2013 at 12:04 am
      cep3700
      Participant

      So happy for you!!!! Such great news! Your strength is amazing, Congrats!

      • November 22, 2013 at 3:05 am
      POW
      Participant

      That's absoutely fantastic news, Amy! Good for you! I was disappointed when you had to get off the MEK but it looks like you're responding just fine to the dabrafenib alone, which some people do. Keep eating healthfully and get a little exercise and maybe your immune system will now be able to kick mel's butt!

      • November 22, 2013 at 3:05 am
      POW
      Participant

      That's absoutely fantastic news, Amy! Good for you! I was disappointed when you had to get off the MEK but it looks like you're responding just fine to the dabrafenib alone, which some people do. Keep eating healthfully and get a little exercise and maybe your immune system will now be able to kick mel's butt!

      • November 22, 2013 at 3:05 am
      POW
      Participant

      That's absoutely fantastic news, Amy! Good for you! I was disappointed when you had to get off the MEK but it looks like you're responding just fine to the dabrafenib alone, which some people do. Keep eating healthfully and get a little exercise and maybe your immune system will now be able to kick mel's butt!

      • November 22, 2013 at 3:43 am
      BrianP
      Participant

      That's awesome Amy!

      So let me get this straight.  You have Mek, Dab, Ipi, and pd1 swimming around that blood of yours.  No wonder that melanoma is crying uncle!  Nice work.

      Brian

      • November 22, 2013 at 3:43 am
      BrianP
      Participant

      That's awesome Amy!

      So let me get this straight.  You have Mek, Dab, Ipi, and pd1 swimming around that blood of yours.  No wonder that melanoma is crying uncle!  Nice work.

      Brian

      • November 22, 2013 at 3:43 am
      BrianP
      Participant

      That's awesome Amy!

      So let me get this straight.  You have Mek, Dab, Ipi, and pd1 swimming around that blood of yours.  No wonder that melanoma is crying uncle!  Nice work.

      Brian

      • November 22, 2013 at 6:27 am
      tasjacques
      Participant

      Amy so happy for you!!! You go girl!!! So many treatments and to see somethin working is great. The vitiligo is something that happens with PD 1 (My husband has it as a respond to PD 1), I don't know if the other treatments also has that side effect …. but it does not matter which one is causing it as long as YOU ARE RESPONDING YEY

      Elenise

        • November 22, 2013 at 3:34 pm
        NYKaren
        Participant

        AMY, I am so thrilled for you! 

        That's our motto—never give up!

        Just out of curiousity (because I'll hopefully be on it too soon), how bad and what were the side effects of the Menkinist?

        xoxo,

        Karen

        • November 22, 2013 at 3:34 pm
        NYKaren
        Participant

        AMY, I am so thrilled for you! 

        That's our motto—never give up!

        Just out of curiousity (because I'll hopefully be on it too soon), how bad and what were the side effects of the Menkinist?

        xoxo,

        Karen

        • November 22, 2013 at 3:34 pm
        NYKaren
        Participant

        AMY, I am so thrilled for you! 

        That's our motto—never give up!

        Just out of curiousity (because I'll hopefully be on it too soon), how bad and what were the side effects of the Menkinist?

        xoxo,

        Karen

        • November 22, 2013 at 11:15 pm
        awillett1991
        Participant

        Karen – my side effects were really bad, I was in the hospital for two days, but this is  not common. I am BRAF v600D so maybe that's why, I don't know. I had a fever of 102.8, delirium, mouth sores, wasn't eating, severe chills, anemia, and slept all the time.  It was a little scary. 

        Amy

        • November 22, 2013 at 11:15 pm
        awillett1991
        Participant

        Karen – my side effects were really bad, I was in the hospital for two days, but this is  not common. I am BRAF v600D so maybe that's why, I don't know. I had a fever of 102.8, delirium, mouth sores, wasn't eating, severe chills, anemia, and slept all the time.  It was a little scary. 

        Amy

        • November 22, 2013 at 11:15 pm
        awillett1991
        Participant

        Karen – my side effects were really bad, I was in the hospital for two days, but this is  not common. I am BRAF v600D so maybe that's why, I don't know. I had a fever of 102.8, delirium, mouth sores, wasn't eating, severe chills, anemia, and slept all the time.  It was a little scary. 

        Amy

        • November 23, 2013 at 11:00 pm
        NYKaren
        Participant

        Thanks, Amy. Yes, that does sound bad. There's nothing quite like waking up in the hospital with no idea how you got there. 

        Thinking of you,

        karen

        • November 23, 2013 at 11:00 pm
        NYKaren
        Participant

        Thanks, Amy. Yes, that does sound bad. There's nothing quite like waking up in the hospital with no idea how you got there. 

        Thinking of you,

        karen

        • November 23, 2013 at 11:00 pm
        NYKaren
        Participant

        Thanks, Amy. Yes, that does sound bad. There's nothing quite like waking up in the hospital with no idea how you got there. 

        Thinking of you,

        karen

      • November 22, 2013 at 6:27 am
      tasjacques
      Participant

      Amy so happy for you!!! You go girl!!! So many treatments and to see somethin working is great. The vitiligo is something that happens with PD 1 (My husband has it as a respond to PD 1), I don't know if the other treatments also has that side effect …. but it does not matter which one is causing it as long as YOU ARE RESPONDING YEY

      Elenise

      • November 22, 2013 at 6:27 am
      tasjacques
      Participant

      Amy so happy for you!!! You go girl!!! So many treatments and to see somethin working is great. The vitiligo is something that happens with PD 1 (My husband has it as a respond to PD 1), I don't know if the other treatments also has that side effect …. but it does not matter which one is causing it as long as YOU ARE RESPONDING YEY

      Elenise

      • December 8, 2013 at 2:41 am
      aldakota22
      Participant

      Thank God for the good news.Keep that PMA .You will Beat the Beast.   Al

      • December 8, 2013 at 2:41 am
      aldakota22
      Participant

      Thank God for the good news.Keep that PMA .You will Beat the Beast.   Al

      • December 8, 2013 at 2:41 am
      aldakota22
      Participant

      Thank God for the good news.Keep that PMA .You will Beat the Beast.   Al

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