PD1 after Ipi – Experiences?
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PD1 after Ipi – Experiences?

› Forums › General Melanoma Community › PD1 after Ipi – Experiences?

  • Post
    • January 17, 2013 at 10:15 pm
    Erinmay22
    Participant

     

    I'm getting ready to start PD1 on Monday.  Had biopsy and new scans taken yesterday (still haven't heard how much my scans have changed in the last 4 weeks…).  
     
    Curious to hear from folks that took Ipi and failed and then took pd1?  What type of results did you see?  I know I've read a number of different things…  

     

    I'm getting ready to start PD1 on Monday.  Had biopsy and new scans taken yesterday (still haven't heard how much my scans have changed in the last 4 weeks…).  
     
    Curious to hear from folks that took Ipi and failed and then took pd1?  What type of results did you see?  I know I've read a number of different things…  
Viewing 8 reply threads
  • Replies
      • January 18, 2013 at 1:24 am
      audgator
      Participant

      My mets grew on ipi and have been shrinking since I started PD1.  I'm into the every-3-months phase now. I wish you the best of responses.   Dan

      • January 18, 2013 at 1:24 am
      audgator
      Participant

      My mets grew on ipi and have been shrinking since I started PD1.  I'm into the every-3-months phase now. I wish you the best of responses.   Dan

      • January 18, 2013 at 1:24 am
      audgator
      Participant

      My mets grew on ipi and have been shrinking since I started PD1.  I'm into the every-3-months phase now. I wish you the best of responses.   Dan

      • January 18, 2013 at 2:09 am
      POW
      Participant

      Dr. Gibney at Moffitt told me the other day that they are now limiting anti-PD-1 clinical trials to people who have already tried ipi. I don't know why, but I assume that anti-PD-1 works well after ipi, maybe even better than before ipi. 

      • January 18, 2013 at 2:09 am
      POW
      Participant

      Dr. Gibney at Moffitt told me the other day that they are now limiting anti-PD-1 clinical trials to people who have already tried ipi. I don't know why, but I assume that anti-PD-1 works well after ipi, maybe even better than before ipi. 

        • January 18, 2013 at 2:30 am
        Erinmay22
        Participant

        thanks guys!  just curious what folks experiences have been so far.  This will be my 3rd treatment I'm trying!  Ready to get started.  The trial nurse did say they are hoping this can be a 1-2 punch with ipi.  The other arms of the trial that I'm in combine ipi and pd1.  But since I've already had it I'll just do the pd1 arm of it.

        I'll keep you posted.  

        • January 18, 2013 at 2:30 am
        Erinmay22
        Participant

        thanks guys!  just curious what folks experiences have been so far.  This will be my 3rd treatment I'm trying!  Ready to get started.  The trial nurse did say they are hoping this can be a 1-2 punch with ipi.  The other arms of the trial that I'm in combine ipi and pd1.  But since I've already had it I'll just do the pd1 arm of it.

        I'll keep you posted.  

        • January 18, 2013 at 4:12 pm
        Erinmay22
        Participant

        FYI – found out the results of my scan today!! Since Dec 18th the tumor (lymph node) has shrunk! From 3.7 cm to 2.8 cm! and still nothing new! The best news is that they are still going to allow me in the pd1 clinical trial! First dose on Monday!

        • January 18, 2013 at 4:12 pm
        Erinmay22
        Participant

        FYI – found out the results of my scan today!! Since Dec 18th the tumor (lymph node) has shrunk! From 3.7 cm to 2.8 cm! and still nothing new! The best news is that they are still going to allow me in the pd1 clinical trial! First dose on Monday!

        • January 18, 2013 at 5:53 pm
        awillett1991
        Participant
        Yay!!! Go Erin!! Best news I’ve heard all day!!

        Have a great weekend – I know you will!

        • January 18, 2013 at 5:53 pm
        awillett1991
        Participant
        Yay!!! Go Erin!! Best news I’ve heard all day!!

        Have a great weekend – I know you will!

        • January 18, 2013 at 5:53 pm
        awillett1991
        Participant
        Yay!!! Go Erin!! Best news I’ve heard all day!!

        Have a great weekend – I know you will!

        • January 19, 2013 at 12:28 am
        Tina D
        Participant

        YAY!! Amy told me you had gotten good news, so I had to come find it 🙂  . This is fantastic all the way around. So So happy! Enjoy your weekend!!

        Tina

        • January 19, 2013 at 12:28 am
        Tina D
        Participant

        YAY!! Amy told me you had gotten good news, so I had to come find it 🙂  . This is fantastic all the way around. So So happy! Enjoy your weekend!!

        Tina

        • January 19, 2013 at 12:28 am
        Tina D
        Participant

        YAY!! Amy told me you had gotten good news, so I had to come find it 🙂  . This is fantastic all the way around. So So happy! Enjoy your weekend!!

        Tina

        • January 20, 2013 at 2:47 pm
        Erinmay22
        Participant

        Tina – thanks!!  🙂  Hope you're having a great weekend!

        • January 20, 2013 at 2:47 pm
        Erinmay22
        Participant

        Tina – thanks!!  🙂  Hope you're having a great weekend!

        • January 20, 2013 at 2:47 pm
        Erinmay22
        Participant

        Tina – thanks!!  🙂  Hope you're having a great weekend!

        • January 18, 2013 at 4:12 pm
        Erinmay22
        Participant

        FYI – found out the results of my scan today!! Since Dec 18th the tumor (lymph node) has shrunk! From 3.7 cm to 2.8 cm! and still nothing new! The best news is that they are still going to allow me in the pd1 clinical trial! First dose on Monday!

        • January 18, 2013 at 7:54 pm
        POW
        Participant

        Erin, that's wonderful news! Actually, BOTH pieces of news– the shrinking tumors AND the PD-1!! Praying for your best response yet!

        • January 18, 2013 at 7:54 pm
        POW
        Participant

        Erin, that's wonderful news! Actually, BOTH pieces of news– the shrinking tumors AND the PD-1!! Praying for your best response yet!

        • January 18, 2013 at 7:54 pm
        POW
        Participant

        Erin, that's wonderful news! Actually, BOTH pieces of news– the shrinking tumors AND the PD-1!! Praying for your best response yet!

        • January 18, 2013 at 2:30 am
        Erinmay22
        Participant

        thanks guys!  just curious what folks experiences have been so far.  This will be my 3rd treatment I'm trying!  Ready to get started.  The trial nurse did say they are hoping this can be a 1-2 punch with ipi.  The other arms of the trial that I'm in combine ipi and pd1.  But since I've already had it I'll just do the pd1 arm of it.

        I'll keep you posted.  

      • January 18, 2013 at 2:09 am
      POW
      Participant

      Dr. Gibney at Moffitt told me the other day that they are now limiting anti-PD-1 clinical trials to people who have already tried ipi. I don't know why, but I assume that anti-PD-1 works well after ipi, maybe even better than before ipi. 

      • February 4, 2013 at 4:12 am
      Erinlisay38
      Participant
      Hi I had Ippi didn’t respond every tumor grew a lot and now have a few new I just had scans blood work and biopsy done last week to get on the PD1 trial I’m just waiting on the call to tell me when I can start I’m getting nervous because I can actually feel changes tumors growing hopeful this may be the answer for us who have failed for the most part on Ipp
      • February 4, 2013 at 4:12 am
      Erinlisay38
      Participant
      Hi I had Ippi didn’t respond every tumor grew a lot and now have a few new I just had scans blood work and biopsy done last week to get on the PD1 trial I’m just waiting on the call to tell me when I can start I’m getting nervous because I can actually feel changes tumors growing hopeful this may be the answer for us who have failed for the most part on Ipp
        • February 12, 2013 at 12:58 am
        Erinlisay38
        Participant
        So update I start my pd1 tomorrow 11:30 am Yay fingers and toes crossed for this treatment to work 🙂
        • February 12, 2013 at 12:58 am
        Erinlisay38
        Participant
        So update I start my pd1 tomorrow 11:30 am Yay fingers and toes crossed for this treatment to work 🙂
        • February 12, 2013 at 12:58 am
        Erinlisay38
        Participant
        So update I start my pd1 tomorrow 11:30 am Yay fingers and toes crossed for this treatment to work 🙂
        • February 12, 2013 at 12:59 am
        Erinlisay38
        Participant
        So update I start my pd1 tomorrow 11:30 am Yay fingers and toes crossed for this treatment to work 🙂
        • February 12, 2013 at 12:59 am
        Erinlisay38
        Participant
        So update I start my pd1 tomorrow 11:30 am Yay fingers and toes crossed for this treatment to work 🙂
        • February 12, 2013 at 12:59 am
        Erinlisay38
        Participant
        So update I start my pd1 tomorrow 11:30 am Yay fingers and toes crossed for this treatment to work 🙂
        • February 18, 2013 at 3:12 pm
        Sandy11
        Participant

        Hi Erin,

        My husband started IPI a couple of months after you.  He has numerous lung mets and the most recent scan shows possible mets just outside his pancreas.  The good news, growth rate on the lung mets appear to have slowed… not shrunk, but slowed down a bit.  We'll take it.  He has a follow up scan to verify the new activity in March.  We had wondered about a possible "next step".  Sounds like PD1 has potential for better results.  Thanks for paving the way and the best of success to you.

        • February 18, 2013 at 3:12 pm
        Sandy11
        Participant

        Hi Erin,

        My husband started IPI a couple of months after you.  He has numerous lung mets and the most recent scan shows possible mets just outside his pancreas.  The good news, growth rate on the lung mets appear to have slowed… not shrunk, but slowed down a bit.  We'll take it.  He has a follow up scan to verify the new activity in March.  We had wondered about a possible "next step".  Sounds like PD1 has potential for better results.  Thanks for paving the way and the best of success to you.

        • February 18, 2013 at 3:12 pm
        Sandy11
        Participant

        Hi Erin,

        My husband started IPI a couple of months after you.  He has numerous lung mets and the most recent scan shows possible mets just outside his pancreas.  The good news, growth rate on the lung mets appear to have slowed… not shrunk, but slowed down a bit.  We'll take it.  He has a follow up scan to verify the new activity in March.  We had wondered about a possible "next step".  Sounds like PD1 has potential for better results.  Thanks for paving the way and the best of success to you.

      • February 4, 2013 at 4:12 am
      Erinlisay38
      Participant
      Hi I had Ippi didn’t respond every tumor grew a lot and now have a few new I just had scans blood work and biopsy done last week to get on the PD1 trial I’m just waiting on the call to tell me when I can start I’m getting nervous because I can actually feel changes tumors growing hopeful this may be the answer for us who have failed for the most part on Ipp
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