I’m not a doctor, but it’s not uncommon for people to experience side effects from immunotherapy treatments like Opdivo (nivolumab) and Yervoy (ipilimumab). It’s positive that your doctor adjusted the dosage of Yervoy after you experienced severe diarrhea, as this suggests a personalized approach to managing side effects.
Weight loss and gastrointestinal issues, including diarrhea, are known side effects of these medications. It’s encouraging that your side effects lessened with subsequent infusions, and your regained weight is a positive sign. Every individual responds differently to these treatments, and adjustments in dosage can sometimes help balance the benefits and side effects.