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opdivo and yervoy side effects

Forums Cutaneous Melanoma Community opdivo and yervoy side effects

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      just wondering of other peoples experience of side effects with this combo. I got quite ill after the 2nd infusion with diarrhea, vomiting, hypotension, nausea, weakness and lost 15 lbs in 2 weeks. I received fluids twice but luckily avoided hospitalization. I had to postpone the 3rd infusion for 2 weeks but am experiencing similar but so far not as severe of side effects which seem to again pick up on the 2nd week. I have 1 more infusion. Though I wasn’t expecting a walk in the park, anybody have anything that worked for them to help manage side effects or similar experiences. thank u
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          After my first infusion of opdivo and yervoy in 2016, I had very bad diarrhea and lost 11 lbs. 9 weeks later I had regained most of the lost weight and received my 2nd dose of opdivo and yervoy. My doctor reduced the dose of yervoy by 50%. I had much less side effects with my 2nd and 3rd opdivo and yervoy infusions.
            Started my first infusion on Oct 31st After having a satellite recurrence five years to the month of my first diagnosis. I was so nervous that I would be really sick but I am grateful that my body is holding up. The things that have been bothering me is itchy skin and sore stomach. I did get a bit constipated the first two weeks but I started taking a daily stool softener so that helped. I tend to get lightheaded/dizzy several times throughout the day but nothing I can’t handle. I got my first headache Pretty bad two days ago but I was thinking maybe it was from caffeine withdrawal ? overall the two treatments I have gotten have not been too bad. My husband still calls me the energizer battery because he feels I have not lost any energy yet I do feel tired every day. I go for surgery to remove two tumors from my foot and ankle on the 14th. Depending on pathology, I may have to do the two other Treatments. If things go well, I will just move to Opdivo. I hope things have gotten better for you with treatment!
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