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Yervoy infusion reaction
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Yervoy infusion reaction

› Forums › General Melanoma Community › Yervoy infusion reaction

  • Post
    • September 19, 2016 at 3:29 pm
    sleepyt23
    Participant

      Hi all,

       

      I was supposed to have my second infusion of 10mg Yervoy this past Friday, but ended up having an infusion reaction about 9-minutes into the session. I started to feel very flushed and had a difficult time breathing. Oddly enough, I didn't have any reaction to the first infusion 3-weeks ago.

       

      Nursing staff stopped the infusion, gave me benadryl, hydrocortisone, oxygen, zantac, and started a saline drip in lieu of the Yervoy.

       

      I fell asleep in the chair for about 30-minutes and felt better, then left and went back to work. The on-call doc (mine was out of office) didn't really say anything but said I would be following up with my doc on what the next step would be. 

       

      Has anyone had this happen before? 

    Viewing 11 reply threads
    • Replies
        • September 20, 2016 at 7:11 pm
        MoiraM
        Participant

          No one has replied, so I thought I would. No, that did not happen to me when I was on Yervoy (Ipi).

          It sounds like an allergic reaction – it being on the second exposure fits with that.

          • September 20, 2016 at 7:11 pm
          MoiraM
          Participant

            No one has replied, so I thought I would. No, that did not happen to me when I was on Yervoy (Ipi).

            It sounds like an allergic reaction – it being on the second exposure fits with that.

              • September 20, 2016 at 8:28 pm
              Aaron
              Participant

                I had a reaction similar to yours. I also broke out in hives. 

                • September 20, 2016 at 8:28 pm
                Aaron
                Participant

                  I had a reaction similar to yours. I also broke out in hives. 

                  • September 20, 2016 at 8:28 pm
                  Aaron
                  Participant

                    I had a reaction similar to yours. I also broke out in hives. 

                  • September 20, 2016 at 7:11 pm
                  MoiraM
                  Participant

                    No one has replied, so I thought I would. No, that did not happen to me when I was on Yervoy (Ipi).

                    It sounds like an allergic reaction – it being on the second exposure fits with that.

                    • September 20, 2016 at 9:29 pm
                    slh4448
                    Participant

                      I had my second 10mg infusion of Yervoy today. Last Thursday would've been exactly three weeks since my first but I was out of town at a sales meeting so I had my second today. I guess so far, so good, but it's only been two hours since I left the facility. I do however feel this random tingling feeling at different parts of my body, nt all at the same time….kinda wondering if it's a prelude to a rash??? It's not terrible (at least yet) and I'm not scratching much at all.

                      • September 20, 2016 at 9:29 pm
                      slh4448
                      Participant

                        I had my second 10mg infusion of Yervoy today. Last Thursday would've been exactly three weeks since my first but I was out of town at a sales meeting so I had my second today. I guess so far, so good, but it's only been two hours since I left the facility. I do however feel this random tingling feeling at different parts of my body, nt all at the same time….kinda wondering if it's a prelude to a rash??? It's not terrible (at least yet) and I'm not scratching much at all.

                        • September 20, 2016 at 9:29 pm
                        slh4448
                        Participant

                          I had my second 10mg infusion of Yervoy today. Last Thursday would've been exactly three weeks since my first but I was out of town at a sales meeting so I had my second today. I guess so far, so good, but it's only been two hours since I left the facility. I do however feel this random tingling feeling at different parts of my body, nt all at the same time….kinda wondering if it's a prelude to a rash??? It's not terrible (at least yet) and I'm not scratching much at all.

                          • September 21, 2016 at 2:43 am
                          Aaron
                          Participant

                            Mine was actually hives that followed a warm sensation in the ears. The feeling was very similar to when you have contrast added during a scan. They gave me benedryl etc.  

                            • September 21, 2016 at 2:43 am
                            Aaron
                            Participant

                              Mine was actually hives that followed a warm sensation in the ears. The feeling was very similar to when you have contrast added during a scan. They gave me benedryl etc.  

                              • September 21, 2016 at 2:43 am
                              Aaron
                              Participant

                                Mine was actually hives that followed a warm sensation in the ears. The feeling was very similar to when you have contrast added during a scan. They gave me benedryl etc.  

                                • September 21, 2016 at 10:59 pm
                                youngann
                                Participant

                                  I get an infusion of Benedry my Ipi infusion even starts.

                                   

                                  • September 21, 2016 at 10:59 pm
                                  youngann
                                  Participant

                                    I get an infusion of Benedry my Ipi infusion even starts.

                                     

                                      • September 22, 2016 at 10:25 pm
                                      slh4448
                                      Participant

                                        Ann…I've not heard of this. So you get an infusion of Benadryl before every IPI infusion, is that correct? If so, how long does that take and does it help you? Also, how many IPI infusions have you had? Thanks!! Stacy

                                        • September 22, 2016 at 10:25 pm
                                        slh4448
                                        Participant

                                          Ann…I've not heard of this. So you get an infusion of Benadryl before every IPI infusion, is that correct? If so, how long does that take and does it help you? Also, how many IPI infusions have you had? Thanks!! Stacy

                                          • September 22, 2016 at 10:25 pm
                                          slh4448
                                          Participant

                                            Ann…I've not heard of this. So you get an infusion of Benadryl before every IPI infusion, is that correct? If so, how long does that take and does it help you? Also, how many IPI infusions have you had? Thanks!! Stacy

                                          • September 21, 2016 at 10:59 pm
                                          youngann
                                          Participant

                                            I get an infusion of Benedry my Ipi infusion even starts.

                                             

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