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XL 184 clinical trial
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XL 184 clinical trial

› Forums › General Melanoma Community › XL 184 clinical trial

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      • March 2, 2012 at 6:27 pm
      jim Breitfeller
      Participant

        Julie,

        XL184, is a potent dual inhibitor of the MET and VEGF pathways designed to block MET driven tumor escape. 

        Are you Braf or Nras Positive?

         

        Jimmy B

          • March 2, 2012 at 8:35 pm
          gabsound
          Participant
            Hi Jimmy,

            NRAS positive

            • March 2, 2012 at 9:00 pm
            jim Breitfeller
            Participant

              You may want look into a clinical trials with a PI3K/Akt/mTOR Inhibitors. You want to stop and kill the tumor cell growth.

               

              • March 3, 2012 at 4:28 am
              kylez
              Participant

                At the clinic I go to they're also very interested in Pi3K for NRAS patients, but particularly in combo Pi3K/MEK trials is what my doctor told me, for their NRAS positive patients. Of which I'm also one (G12A mutation).

                • March 3, 2012 at 4:28 am
                kylez
                Participant

                  At the clinic I go to they're also very interested in Pi3K for NRAS patients, but particularly in combo Pi3K/MEK trials is what my doctor told me, for their NRAS positive patients. Of which I'm also one (G12A mutation).

                  • March 3, 2012 at 4:28 am
                  kylez
                  Participant

                    At the clinic I go to they're also very interested in Pi3K for NRAS patients, but particularly in combo Pi3K/MEK trials is what my doctor told me, for their NRAS positive patients. Of which I'm also one (G12A mutation).

                    • March 2, 2012 at 9:00 pm
                    jim Breitfeller
                    Participant

                      You may want look into a clinical trials with a PI3K/Akt/mTOR Inhibitors. You want to stop and kill the tumor cell growth.

                       

                      • March 2, 2012 at 9:00 pm
                      jim Breitfeller
                      Participant

                        You may want look into a clinical trials with a PI3K/Akt/mTOR Inhibitors. You want to stop and kill the tumor cell growth.

                         

                        • March 2, 2012 at 8:35 pm
                        gabsound
                        Participant
                          Hi Jimmy,

                          NRAS positive

                          • March 2, 2012 at 8:35 pm
                          gabsound
                          Participant
                            Hi Jimmy,

                            NRAS positive

                          • March 2, 2012 at 6:27 pm
                          jim Breitfeller
                          Participant

                            Julie,

                            XL184, is a potent dual inhibitor of the MET and VEGF pathways designed to block MET driven tumor escape. 

                            Are you Braf or Nras Positive?

                             

                            Jimmy B

                            • March 2, 2012 at 6:27 pm
                            jim Breitfeller
                            Participant

                              Julie,

                              XL184, is a potent dual inhibitor of the MET and VEGF pathways designed to block MET driven tumor escape. 

                              Are you Braf or Nras Positive?

                               

                              Jimmy B

                          Viewing 2 reply threads
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