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Triall on patients with melanoma spread to their brain.

Forums General Melanoma Community Triall on patients with melanoma spread to their brain.

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      LuckyMan51
      Participant

        Thanks Jerry, Well timed post for me! Just shot my Onc a note asking about a fit for my plan B. Much appreciated.   

        LuckyMan51
        Participant

          Thanks Jerry, Well timed post for me! Just shot my Onc a note asking about a fit for my plan B. Much appreciated.   

          LuckyMan51
          Participant

            Thanks Jerry, Well timed post for me! Just shot my Onc a note asking about a fit for my plan B. Much appreciated.   

              tschmith
              Participant

                Good to hear from you, Jerry!  Hope all is well.

                Terrie

                tschmith
                Participant

                  Good to hear from you, Jerry!  Hope all is well.

                  Terrie

                  tschmith
                  Participant

                    Good to hear from you, Jerry!  Hope all is well.

                    Terrie

                    mary1233
                    Participant

                      Metastisis to the brain is my biggest fear. Thank you for finding this. Does anyone know if this trial is being duplicated in the US?

                      Best wishes to all.

                      Mary

                      mary1233
                      Participant

                        Metastisis to the brain is my biggest fear. Thank you for finding this. Does anyone know if this trial is being duplicated in the US?

                        Best wishes to all.

                        Mary

                        mary1233
                        Participant

                          Metastisis to the brain is my biggest fear. Thank you for finding this. Does anyone know if this trial is being duplicated in the US?

                          Best wishes to all.

                          Mary

                        rick1981
                        Participant

                          Great news, they used to exclude patients with brain mets from PD1 trials. It seems there are 3 legs: Opdivo/nivolumab, Opdivo/nivolumab + Yervoy/ipilimumab and radiation (not clear if it's with Opdivo).

                          My wife's not in a trial but she progressed on the BRAF/MEK combo and developed 12 brain mets, either in the "free fall" period before moving onto PD1 or whilst already on PD1. Anyway, she was allowed to continue and is now having Keytruda/pembrolizumab (4th infusion yesterday), had 5 days of whole brain radiation and today had radiation of her hips (bone mets).

                          Will keep everyone posted – even though she's not on a trial,

                          Rick 

                          rick1981
                          Participant

                            Great news, they used to exclude patients with brain mets from PD1 trials. It seems there are 3 legs: Opdivo/nivolumab, Opdivo/nivolumab + Yervoy/ipilimumab and radiation (not clear if it's with Opdivo).

                            My wife's not in a trial but she progressed on the BRAF/MEK combo and developed 12 brain mets, either in the "free fall" period before moving onto PD1 or whilst already on PD1. Anyway, she was allowed to continue and is now having Keytruda/pembrolizumab (4th infusion yesterday), had 5 days of whole brain radiation and today had radiation of her hips (bone mets).

                            Will keep everyone posted – even though she's not on a trial,

                            Rick 

                            rick1981
                            Participant

                              Great news, they used to exclude patients with brain mets from PD1 trials. It seems there are 3 legs: Opdivo/nivolumab, Opdivo/nivolumab + Yervoy/ipilimumab and radiation (not clear if it's with Opdivo).

                              My wife's not in a trial but she progressed on the BRAF/MEK combo and developed 12 brain mets, either in the "free fall" period before moving onto PD1 or whilst already on PD1. Anyway, she was allowed to continue and is now having Keytruda/pembrolizumab (4th infusion yesterday), had 5 days of whole brain radiation and today had radiation of her hips (bone mets).

                              Will keep everyone posted – even though she's not on a trial,

                              Rick 

                                eturner82
                                Participant

                                  Hi Rick

                                  Please due keep us posted on your wife, my hubby has bone mets and lung mets and I am very interested in how the PD1 is helping with the bone mets…. my hubby will receive 2nd dose of PD1 tomorrow.

                                  Thanks

                                  Emily

                                  eturner82
                                  Participant

                                    Hi Rick

                                    Please due keep us posted on your wife, my hubby has bone mets and lung mets and I am very interested in how the PD1 is helping with the bone mets…. my hubby will receive 2nd dose of PD1 tomorrow.

                                    Thanks

                                    Emily

                                    eturner82
                                    Participant

                                      Hi Rick

                                      Please due keep us posted on your wife, my hubby has bone mets and lung mets and I am very interested in how the PD1 is helping with the bone mets…. my hubby will receive 2nd dose of PD1 tomorrow.

                                      Thanks

                                      Emily

                                      rick1981
                                      Participant

                                        Will do – you can also search posts to see our history. Good luck with the 2nd treatment! Rick

                                        rick1981
                                        Participant

                                          Will do – you can also search posts to see our history. Good luck with the 2nd treatment! Rick

                                          rick1981
                                          Participant

                                            Will do – you can also search posts to see our history. Good luck with the 2nd treatment! Rick

                                          ed williams
                                          Participant

                                            Thanks for the post Jerry!!!! I have been following " Jennifer's Journey " on facebook, she is one of the luck ones to get into the trial in Australia and has just finished her 4th dose of Nivolumab. She is friends with one of the great leaders in Melamona awareness in Australia (Jay Allen). He has been one of the main fighters to get sun tanning beds banned in Australia. I wish every one the best, in their Melanoma journey's. Ed

                                            ed williams
                                            Participant

                                              Thanks for the post Jerry!!!! I have been following " Jennifer's Journey " on facebook, she is one of the luck ones to get into the trial in Australia and has just finished her 4th dose of Nivolumab. She is friends with one of the great leaders in Melamona awareness in Australia (Jay Allen). He has been one of the main fighters to get sun tanning beds banned in Australia. I wish every one the best, in their Melanoma journey's. Ed

                                              ed williams
                                              Participant

                                                Thanks for the post Jerry!!!! I have been following " Jennifer's Journey " on facebook, she is one of the luck ones to get into the trial in Australia and has just finished her 4th dose of Nivolumab. She is friends with one of the great leaders in Melamona awareness in Australia (Jay Allen). He has been one of the main fighters to get sun tanning beds banned in Australia. I wish every one the best, in their Melanoma journey's. Ed

                                                Bubbles
                                                Participant

                                                  Yay!  YAY!  YAY!  And a few….It's about time!!!! (s)!!!!  Here's some data I've been YELLING to back up the approach if one is interested!!  Thanks for sharing, Jerry!

                                                  http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/02/ipi-nivo-combo-and-radiation-for.html

                                                  Celeste

                                                  Bubbles
                                                  Participant

                                                    Yay!  YAY!  YAY!  And a few….It's about time!!!! (s)!!!!  Here's some data I've been YELLING to back up the approach if one is interested!!  Thanks for sharing, Jerry!

                                                    http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/02/ipi-nivo-combo-and-radiation-for.html

                                                    Celeste

                                                    Bubbles
                                                    Participant

                                                      Yay!  YAY!  YAY!  And a few….It's about time!!!! (s)!!!!  Here's some data I've been YELLING to back up the approach if one is interested!!  Thanks for sharing, Jerry!

                                                      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/02/ipi-nivo-combo-and-radiation-for.html

                                                      Celeste

                                                        csellers23
                                                        Participant
                                                          Is this keytruda?
                                                          csellers23
                                                          Participant
                                                            Is this keytruda?
                                                            csellers23
                                                            Participant
                                                              Is this keytruda?
                                                              BrianP
                                                              Participant

                                                                Crystal,

                                                                If I understand your question you are wondering in the first post by Jerry if the drug referred to as nivolumab is Keytruda.  If that's your question the answer is no.

                                                                Kinda confusing but most drugs start out with what I like to call their chemical name and then later they get a commercial name.  There are two big players on the anti-PD1 scene right now.  One is BMS's drug which is nivolumab and is now being marketed as Opdivo.  The second is Merck's pembrolizumab which is now being marketed as Keytruda.  Both drugs are anti-PD1 inhibitors and both drugs have had very similar results on patients with maybe a slight edge to Keytruda but it's probably to early to say for sure.  Hope this answers your question.

                                                                Brian

                                                                BrianP
                                                                Participant

                                                                  Crystal,

                                                                  If I understand your question you are wondering in the first post by Jerry if the drug referred to as nivolumab is Keytruda.  If that's your question the answer is no.

                                                                  Kinda confusing but most drugs start out with what I like to call their chemical name and then later they get a commercial name.  There are two big players on the anti-PD1 scene right now.  One is BMS's drug which is nivolumab and is now being marketed as Opdivo.  The second is Merck's pembrolizumab which is now being marketed as Keytruda.  Both drugs are anti-PD1 inhibitors and both drugs have had very similar results on patients with maybe a slight edge to Keytruda but it's probably to early to say for sure.  Hope this answers your question.

                                                                  Brian

                                                                  BrianP
                                                                  Participant

                                                                    Crystal,

                                                                    If I understand your question you are wondering in the first post by Jerry if the drug referred to as nivolumab is Keytruda.  If that's your question the answer is no.

                                                                    Kinda confusing but most drugs start out with what I like to call their chemical name and then later they get a commercial name.  There are two big players on the anti-PD1 scene right now.  One is BMS's drug which is nivolumab and is now being marketed as Opdivo.  The second is Merck's pembrolizumab which is now being marketed as Keytruda.  Both drugs are anti-PD1 inhibitors and both drugs have had very similar results on patients with maybe a slight edge to Keytruda but it's probably to early to say for sure.  Hope this answers your question.

                                                                    Brian

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