Trial Results published: Adoptive Cell Transfer….at DFCI.
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Trial Results published: Adoptive Cell Transfer….at DFCI.

› Forums › General Melanoma Community › Trial Results published: Adoptive Cell Transfer….at DFCI.

  • Post
    • May 10, 2011 at 4:09 am
    Rocco
    Participant

    In March 2008 I participated in a pilot/Phase I trial at DFCI called, "Adoptive Cell Transfer of  Mart1/MelanA for Malignant Melanoma" during which I experienced a mixed result – significant shrinkage of a pulmonary tumor and a slight growth in another.  I am a firm believer that this trial aided my success with ipi in the  MDX-010 Compassionate Use trial that I entered into in August 2008.

    In March 2008 I participated in a pilot/Phase I trial at DFCI called, "Adoptive Cell Transfer of  Mart1/MelanA for Malignant Melanoma" during which I experienced a mixed result – significant shrinkage of a pulmonary tumor and a slight growth in another.  I am a firm believer that this trial aided my success with ipi in the  MDX-010 Compassionate Use trial that I entered into in August 2008.

    Results of the 9 person Adoptive Cell trial were published on April 27th.  Here is a short overview of the trial from the DFCI website with an interview with Dr. Marc Butler. 

    http://www.dana-farber.org/Newsroom/News-Releases/New-technique-extends-cancer-fighting-cells’-potency-in-melanoma-patients.aspx 

    JimmyB if you're reading this, the full trial results may be of interest to you…

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  • Replies
      • May 10, 2011 at 5:14 am
      Ali
      Participant

      That is great news!  So glad something worked for you!  What does Mart1/MelanA mean?  I think the pathology on my recurrence said it was MART1 positive.  Was that the case with your tumors?

      Ali

        • May 10, 2011 at 6:08 am
        Vermont_Donna
        Participant

        Wow, I read the whole study and its impressive, and provides hope! I am so happy for your response. I too, like Ali above, have Mart 1 positive melanoma, so am wondering about that. Thanks for sharing this article and the news about you Rocco.

        Vermont_Donna, stage 3a

        NED after 4 infusions of Ipi

        • May 10, 2011 at 6:08 am
        Vermont_Donna
        Participant

        Wow, I read the whole study and its impressive, and provides hope! I am so happy for your response. I too, like Ali above, have Mart 1 positive melanoma, so am wondering about that. Thanks for sharing this article and the news about you Rocco.

        Vermont_Donna, stage 3a

        NED after 4 infusions of Ipi

      • May 10, 2011 at 5:14 am
      Ali
      Participant

      That is great news!  So glad something worked for you!  What does Mart1/MelanA mean?  I think the pathology on my recurrence said it was MART1 positive.  Was that the case with your tumors?

      Ali

      • May 10, 2011 at 7:23 am
      FormerCaregiver
      Participant

      That's wonderful news! Thanks for posting the results of adoptive cell transfer trial. I am
      convinced that this approach holds a great deal of promise. Maybe this will become the standard
      way that they will treat melanoma in 5 to 10 years time?

      Frank from Australia

      • May 10, 2011 at 7:23 am
      FormerCaregiver
      Participant

      That's wonderful news! Thanks for posting the results of adoptive cell transfer trial. I am
      convinced that this approach holds a great deal of promise. Maybe this will become the standard
      way that they will treat melanoma in 5 to 10 years time?

      Frank from Australia

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