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Taf/Mek long term user

Forums General Melanoma Community Taf/Mek long term user

  • Post
    mom3girlsFL
    Participant

    Hi Friends!

    Longtime member, frequent lurker…sadly, not much of a poster.

     

    I have been on this forum since (roughly) 2003. There have been many people here who I've been blessed to journey with and many more who I've been able to learn from. There have been times when I've  "stepped away", sometimes because it can be so overwhelming, and sometimes because of battles being lost by the most courageous warriors. I am so grateful to you all who continue to regularly post and update and share information.

    With so many current stories of people battling-people who you cant help but love,  I thought maybe my past year (year and a half) could offer optimism and hope.

    2003 stage 1.  2010 groin dissection, start interferon…later 2010 fail interferon, inguinal node surgery. Clear scans, watch and wait. 2015 stage 4 lung, retroperinoteal lymph nodes, para-aortic lymph nodes.

    Started Taf/Mek combo-cant remember if we were into 2016 by this time.  Immediate responder! It hasn't  been easy, have changed dosing, switched to zelboraf/cotellic (was bad!), took only taf for a while, have had a couple med "vacations"…currently full dose.

    So far 3 scans (last one December) have shown no recurrence. I continue to try and stay cautiously optimistic about the future knowing, statisically, things can change.

    Dont know if anyone else here has been on T/M this long as well?

    Anyway, much love to all!

    Laurie

     

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      UBContributor
      Participant

      thank you for sharing! your case offeres so much hope . 

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      marta010
      Participant

      Hi Laurie – my husband has been on varying doses of Tafinlar/MEK since Sept 2013.  He had an initial reduction in tumor load and was stable – never NED – until March of 2016.  He's been on 3/4 dose of Tafinlar as a single agent as he had too many side effects with the combo.  Transitioned to Keytruda and tolerated 7 infusions, all the while continued to take Tafinlar as a second line of defense.  He finally showed a response in Feb 2017 – waiting until his next scans in May to see if his tumors continue to shrink and, if so, his oncologist may decrease or stop the Tafinlar.  I hope you continue to see a good response.  Take care.

      Ann

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      uccio2014
      Participant

      Here my wife experience, if can help

      surgey on jul 2013

      stage IV on agust 2014 (multiple metastasis sites)

      On zelboraf from august with quick stable response

      Brian metastasis on jul 2015 body stable

      WBR

      on anti -braf+ anti-mek from october 15

      At now stable (the size of all the meet are really small and both RMN for brain and TAC for body cannot assure if it are metastasis or dead cells

      sorry for my english :-)

       

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