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surgical incision infection treated for 10 days with antibiotics disqualify for pd1 trial?

Forums General Melanoma Community surgical incision infection treated for 10 days with antibiotics disqualify for pd1 trial?

  • Post
    Amanda
    Participant

      Do any of you know if being on antibiotics for an infected surgical incision will disqualify you from Merk's Anti-pd1 trial?   My boyfriend is about 5 days through the 10 day cycle of antibiotics, But the incision site is still draining and has pus, although it's not red or inflamed.    He is due to meet with Dr.

      Do any of you know if being on antibiotics for an infected surgical incision will disqualify you from Merk's Anti-pd1 trial?   My boyfriend is about 5 days through the 10 day cycle of antibiotics, But the incision site is still draining and has pus, although it's not red or inflamed.    He is due to meet with Dr. to assess him for a trial of anti-pd1 for people who progressed after yervoy, and im worried having an active healing infection, and being on antibiotics will disqualify him…even though he only has another 5 days or so of the antibiotic.  I'm also worried that having a prior bowel obstruction surgery will disqualify him.  Any opinions would be greatly appreciated. Thanks in advance

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        Josh
        Participant

          Hey,

           

          I'm not an expert here, but I don't see why antibiotics, a healing infection, or a previous surgery would disqualify one from the anti pd-a trial. As far as I know, previous surgeries are totally irrelevant (I've had many surgeries and I'm on Merk's trial). As for anitbiotics, it may be that he'll need to have 1-3 weeks pass before they'll let him start the drug, though I'm pretty sure this only becomes relevant if you're on other treatments. For example, I was on the BRAF drug before I started Merk's trial, so had to have a 3 week "wash" before beginning. I don't however believe that this would be the case with antibiotics. Best of luck!

          Josh
          Participant

            Hey,

             

            I'm not an expert here, but I don't see why antibiotics, a healing infection, or a previous surgery would disqualify one from the anti pd-a trial. As far as I know, previous surgeries are totally irrelevant (I've had many surgeries and I'm on Merk's trial). As for anitbiotics, it may be that he'll need to have 1-3 weeks pass before they'll let him start the drug, though I'm pretty sure this only becomes relevant if you're on other treatments. For example, I was on the BRAF drug before I started Merk's trial, so had to have a 3 week "wash" before beginning. I don't however believe that this would be the case with antibiotics. Best of luck!

            Josh
            Participant

              Hey,

               

              I'm not an expert here, but I don't see why antibiotics, a healing infection, or a previous surgery would disqualify one from the anti pd-a trial. As far as I know, previous surgeries are totally irrelevant (I've had many surgeries and I'm on Merk's trial). As for anitbiotics, it may be that he'll need to have 1-3 weeks pass before they'll let him start the drug, though I'm pretty sure this only becomes relevant if you're on other treatments. For example, I was on the BRAF drug before I started Merk's trial, so had to have a 3 week "wash" before beginning. I don't however believe that this would be the case with antibiotics. Best of luck!

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