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Side effects and in a trial

Forums General Melanoma Community Side effects and in a trial

  • Post
    Ninniditti
    Participant

      Hi!

      I am in a trial, nivolumab/dacarbazin. If I suffer from side effects such as colite can I still be part of the trial or do I have to pause the trial until I am cured from the side effect. Can I be totally neglected to go on with the trial.  if I have another cancer than melanoma in my guts can I still be in the trial. I have blood and slime in my stools and suppose I have to report this to the doctors in the trial. I so want to go on with the trial.  I am hoping for answer. 

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    • Replies
        Bubbles
        Participant

          Hi Ninniditti,

          The important thing to know is that any immunotherapy (ipi/yervoy, any of the anti-PD1 products) can cause colitis…inflammation of the intestinal track…that can result in diarrhea, abdominal pain, stools as you describe, dehydration, etc.  At this point I think it is imperative that you let your doctor know about your symptoms so that they can be helped before they become worse.  I doubt your symptoms are caused by some other sort of cancer, rather they are much more likely to be due to your treatment.  As to whether or not you can remain on the trial depends on the criteria of your particular trial.  It also depends on whether your body can tolerate the treatment or not.  I don't want you to get any sicker, so please talk to your doctor and they can give you medicines to help you feel better and then decide what you should do next.

          Wishing you the best. Celeste

          Bubbles
          Participant

            Hi Ninniditti,

            The important thing to know is that any immunotherapy (ipi/yervoy, any of the anti-PD1 products) can cause colitis…inflammation of the intestinal track…that can result in diarrhea, abdominal pain, stools as you describe, dehydration, etc.  At this point I think it is imperative that you let your doctor know about your symptoms so that they can be helped before they become worse.  I doubt your symptoms are caused by some other sort of cancer, rather they are much more likely to be due to your treatment.  As to whether or not you can remain on the trial depends on the criteria of your particular trial.  It also depends on whether your body can tolerate the treatment or not.  I don't want you to get any sicker, so please talk to your doctor and they can give you medicines to help you feel better and then decide what you should do next.

            Wishing you the best. Celeste

            Bubbles
            Participant

              Hi Ninniditti,

              The important thing to know is that any immunotherapy (ipi/yervoy, any of the anti-PD1 products) can cause colitis…inflammation of the intestinal track…that can result in diarrhea, abdominal pain, stools as you describe, dehydration, etc.  At this point I think it is imperative that you let your doctor know about your symptoms so that they can be helped before they become worse.  I doubt your symptoms are caused by some other sort of cancer, rather they are much more likely to be due to your treatment.  As to whether or not you can remain on the trial depends on the criteria of your particular trial.  It also depends on whether your body can tolerate the treatment or not.  I don't want you to get any sicker, so please talk to your doctor and they can give you medicines to help you feel better and then decide what you should do next.

              Wishing you the best. Celeste

              LuckyMan51
              Participant

                You should inform your Oncologist immediately. Perhaps your symptoms can be eased by steroids or a short pause and you can remain in the trail vs your suffering worsening complications that might require hospitalization and your being pulled from the trail. I think we all understand your difficulty with the decision but it would certainly be a shame to kill yourself while trying to save yourself. Good luck. 

                LuckyMan51
                Participant

                  You should inform your Oncologist immediately. Perhaps your symptoms can be eased by steroids or a short pause and you can remain in the trail vs your suffering worsening complications that might require hospitalization and your being pulled from the trail. I think we all understand your difficulty with the decision but it would certainly be a shame to kill yourself while trying to save yourself. Good luck. 

                  LuckyMan51
                  Participant

                    You should inform your Oncologist immediately. Perhaps your symptoms can be eased by steroids or a short pause and you can remain in the trail vs your suffering worsening complications that might require hospitalization and your being pulled from the trail. I think we all understand your difficulty with the decision but it would certainly be a shame to kill yourself while trying to save yourself. Good luck. 

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