› Forums › General Melanoma Community › Side effects and in a trial
- This topic has 6 replies, 2 voices, and was last updated 10 years, 2 months ago by LuckyMan51.
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- February 24, 2014 at 5:32 pm
Hi!
I am in a trial, nivolumab/dacarbazin. If I suffer from side effects such as colite can I still be part of the trial or do I have to pause the trial until I am cured from the side effect. Can I be totally neglected to go on with the trial. if I have another cancer than melanoma in my guts can I still be in the trial. I have blood and slime in my stools and suppose I have to report this to the doctors in the trial. I so want to go on with the trial. I am hoping for answer.
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- February 24, 2014 at 11:46 pm
Hi Ninniditti,
The important thing to know is that any immunotherapy (ipi/yervoy, any of the anti-PD1 products) can cause colitis…inflammation of the intestinal track…that can result in diarrhea, abdominal pain, stools as you describe, dehydration, etc. At this point I think it is imperative that you let your doctor know about your symptoms so that they can be helped before they become worse. I doubt your symptoms are caused by some other sort of cancer, rather they are much more likely to be due to your treatment. As to whether or not you can remain on the trial depends on the criteria of your particular trial. It also depends on whether your body can tolerate the treatment or not. I don't want you to get any sicker, so please talk to your doctor and they can give you medicines to help you feel better and then decide what you should do next.
Wishing you the best. Celeste
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- February 24, 2014 at 11:46 pm
Hi Ninniditti,
The important thing to know is that any immunotherapy (ipi/yervoy, any of the anti-PD1 products) can cause colitis…inflammation of the intestinal track…that can result in diarrhea, abdominal pain, stools as you describe, dehydration, etc. At this point I think it is imperative that you let your doctor know about your symptoms so that they can be helped before they become worse. I doubt your symptoms are caused by some other sort of cancer, rather they are much more likely to be due to your treatment. As to whether or not you can remain on the trial depends on the criteria of your particular trial. It also depends on whether your body can tolerate the treatment or not. I don't want you to get any sicker, so please talk to your doctor and they can give you medicines to help you feel better and then decide what you should do next.
Wishing you the best. Celeste
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- February 24, 2014 at 11:46 pm
Hi Ninniditti,
The important thing to know is that any immunotherapy (ipi/yervoy, any of the anti-PD1 products) can cause colitis…inflammation of the intestinal track…that can result in diarrhea, abdominal pain, stools as you describe, dehydration, etc. At this point I think it is imperative that you let your doctor know about your symptoms so that they can be helped before they become worse. I doubt your symptoms are caused by some other sort of cancer, rather they are much more likely to be due to your treatment. As to whether or not you can remain on the trial depends on the criteria of your particular trial. It also depends on whether your body can tolerate the treatment or not. I don't want you to get any sicker, so please talk to your doctor and they can give you medicines to help you feel better and then decide what you should do next.
Wishing you the best. Celeste
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- February 25, 2014 at 8:28 pm
You should inform your Oncologist immediately. Perhaps your symptoms can be eased by steroids or a short pause and you can remain in the trail vs your suffering worsening complications that might require hospitalization and your being pulled from the trail. I think we all understand your difficulty with the decision but it would certainly be a shame to kill yourself while trying to save yourself. Good luck.
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- February 25, 2014 at 8:28 pm
You should inform your Oncologist immediately. Perhaps your symptoms can be eased by steroids or a short pause and you can remain in the trail vs your suffering worsening complications that might require hospitalization and your being pulled from the trail. I think we all understand your difficulty with the decision but it would certainly be a shame to kill yourself while trying to save yourself. Good luck.
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- February 25, 2014 at 8:28 pm
You should inform your Oncologist immediately. Perhaps your symptoms can be eased by steroids or a short pause and you can remain in the trail vs your suffering worsening complications that might require hospitalization and your being pulled from the trail. I think we all understand your difficulty with the decision but it would certainly be a shame to kill yourself while trying to save yourself. Good luck.
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