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Pan Raf inhibitor trial

Forums General Melanoma Community Pan Raf inhibitor trial

  • Post
    Lilara
    Participant
      Hi , My mom she has NRaS mutation and she has a tumor in her pelvis which is growing slowly and she is currently on immunotherapy . The doctor is saying maybe we should try pan raf trial. Does anyone know more about this or have done this . Since we are in Canada IpI / nivo together is not available after progression on keytruda . We need to pay out of pocket which I am considering at least for the 4 does that is needed .  Also I am planning to take her to Washington DC where I live , any Dr and melanoma surgeon that you can recommend will be appreciate it.

      Any advice is needed .

      thanks

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    • Replies
        Mark_DC
        Participant
          Dear Lilara

          sorry i can only answer briefly but for DC i know the following doctors:

          Dr. Rapisuwon at Washington Hospital Center (he treats me and may have saved my life)

          also Dr. Gibney at at Georgetown (treated me before)

          Dr. Lipson at Sibley Hospital (Johns Hopkins) – great second opinions for me

          there is also a unit at INOVA Fairfax Hospital that is supposed to be good

          not sure if any of these know about the trial you are mentioning but do please update as i am NRAS too

          These doctors can recommend surgeons too

          hope this helps a little and that your mother will do well

          best wishes Mark

          Christinad
          Participant
            Hi – how do you know if you have an NRAS mutation? When I was initially diagnosed in 2014, I remember that I am BRAF negative but I don’t remember being told anything about NRAS.
            Mark_DC
            Participant
              Hi Lilara, ipi nivo would seem normal even for us NRAS types – would need good arguments to go for this trial instead. Hope you can find a good doctor, especially if your mum comes to DC
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