Not too shabby results on an Ipi Study

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Not too shabby results on an Ipi Study

This topic has 3 replies, 1 voice, and was last updated 11 years ago by Roxy1453.

Post

- September 28, 2013 at 4:21 pm
- Quote
Linny
Participant
Past President of ECCO, Professor Alexander Eggermont, Directeur Général of the Institut Gustave Roussy Comprehensive Cancer Center (France), who specialises in the treatment of melanoma, commented: "This pooled analysis clearly demonstrates that ipilimumab can lead to long-lasting tumour control in metastatic melanoma patients. With a response rate of only 10-15%, one can achieve more than 3-10 years survival in 17-25% of patients who have received only a few doses of ipilimumab. Thus, patients apparently can keep residual tumours under control for a long time when the immune system is properly 'reset', and the concept of 'clinical cures' becomes a reality. These survival results could even double or triple with anti-PD1/PDL1 monoclonal antibodies, and metastatic melanoma could become a curable disease for perhaps more than 50% of patients over the coming 5-10 years."

http://esciencenews.com/articles/2013/09/27/longest.follow.melanoma.patients.treated.with.ipilimumab.shows.some.survive.10.years

Considering where we were with Melanoma even as recently as 2010, this is pretty astounding.

I just with there was a way to "fast forward" Anti-PD1/PDL1 and get it on the market.

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Replies

- - September 29, 2013 at 8:42 pm
  - Quote
  Roxy1453
  Participant
  I could be one of the lucky ones responding to IPI:-). My Dr was sure my Mel was back in my lung. I had a biop and it showed it was not Mel! He thinks the IPI taught my body to fight the Mel cells and it was Mel but now is gone!
  I go back for another CT Oct 11. If the spot has grown this is all out the window and he’s taking it out. So, more wait and see!
  This is all so promising thought.
- - September 29, 2013 at 8:42 pm
  - Quote
  Roxy1453
  Participant
  I could be one of the lucky ones responding to IPI:-). My Dr was sure my Mel was back in my lung. I had a biop and it showed it was not Mel! He thinks the IPI taught my body to fight the Mel cells and it was Mel but now is gone!
  I go back for another CT Oct 11. If the spot has grown this is all out the window and he’s taking it out. So, more wait and see!
  This is all so promising thought.
- - September 29, 2013 at 8:42 pm
  - Quote
  Roxy1453
  Participant
  I could be one of the lucky ones responding to IPI:-). My Dr was sure my Mel was back in my lung. I had a biop and it showed it was not Mel! He thinks the IPI taught my body to fight the Mel cells and it was Mel but now is gone!
  I go back for another CT Oct 11. If the spot has grown this is all out the window and he’s taking it out. So, more wait and see!
  This is all so promising thought.

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