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My Trial Has Started!

Forums General Melanoma Community My Trial Has Started!

  • Post
    Eileen L
    Participant

    The first day of my BRAF/MEK trial was yesterday! Everything went well. I essentially had to be at the hospital all day because they were drawing blood every 1-2 hours. Today I have to go back to get another blood draw as well as an EKG. I did receive a schedule of my appointments for the next eight weeks and I will be tied up 1-2 days a week, getting various tests and scans. Only one other all day session, however.

    The first day of my BRAF/MEK trial was yesterday! Everything went well. I essentially had to be at the hospital all day because they were drawing blood every 1-2 hours. Today I have to go back to get another blood draw as well as an EKG. I did receive a schedule of my appointments for the next eight weeks and I will be tied up 1-2 days a week, getting various tests and scans. Only one other all day session, however. Most of the other appointments are half days!

     
    I am very optimistic about these drugs, the response rates have been very good and I responded very well to a less potent drug for over four years. I get a scan at the end of June which will evaluate how I am doing. Until then, I am as usual trying to live my life to its fullest. We are going away for a few days today and I have brought with me a full array of sun protection, including sun protective clothing, wide brimmed hats, sunscreen, etc. 
     
    Will let everyone know how it goes.
     
    Eileen L
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Viewing 17 reply threads
  • Replies
      Harry in Fair Oaks
      Participant

      Congrats Eileen!  I wish you all the best.  As you know, I'm on the GSK version of the BRAF/MEK trial.  There was preliminary data from my trial released a couple of days ago showing great things, and GSK is now going to proceed with a Stage III trial of this "cocktail."  And I'm betting on similar results from your study.

      Best wishes,

      Harry

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      Harry in Fair Oaks
      Participant

      Congrats Eileen!  I wish you all the best.  As you know, I'm on the GSK version of the BRAF/MEK trial.  There was preliminary data from my trial released a couple of days ago showing great things, and GSK is now going to proceed with a Stage III trial of this "cocktail."  And I'm betting on similar results from your study.

      Best wishes,

      Harry

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        Eileen L
        Participant
        Thanks for the update on your trial and your good wishes. I am feeling very hopeful about this drug combo as well!
        Eileen L

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        Eileen L
        Participant
        Thanks for the update on your trial and your good wishes. I am feeling very hopeful about this drug combo as well!
        Eileen L

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        Eileen L
        Participant
        Thanks for the update on your trial and your good wishes. I am feeling very hopeful about this drug combo as well!
        Eileen L

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      Harry in Fair Oaks
      Participant

      Congrats Eileen!  I wish you all the best.  As you know, I'm on the GSK version of the BRAF/MEK trial.  There was preliminary data from my trial released a couple of days ago showing great things, and GSK is now going to proceed with a Stage III trial of this "cocktail."  And I'm betting on similar results from your study.

      Best wishes,

      Harry

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      aldakota22
      Participant

      Good for you Eileen.May this trial be the answer you are looking for,so you can live life fully for a very long time.My prayers go with you.   Al

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      aldakota22
      Participant

      Good for you Eileen.May this trial be the answer you are looking for,so you can live life fully for a very long time.My prayers go with you.   Al

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        Eileen L
        Participant
        Thanks!
        Eileen L

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        Eileen L
        Participant
        Thanks!
        Eileen L

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        Eileen L
        Participant
        Thanks!
        Eileen L

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      aldakota22
      Participant

      Good for you Eileen.May this trial be the answer you are looking for,so you can live life fully for a very long time.My prayers go with you.   Al

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      NYKaren
      Participant
      Great news, Eileen. My thoughts and prayers are with you.
      Looking forward to hearing about that vacation too!
      karen

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        Eileen L
        Participant
        Thx Karen!
        Eileen L

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        Eileen L
        Participant
        Thx Karen!
        Eileen L

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        Eileen L
        Participant
        Thx Karen!
        Eileen L

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      NYKaren
      Participant
      Great news, Eileen. My thoughts and prayers are with you.
      Looking forward to hearing about that vacation too!
      karen

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      NYKaren
      Participant
      Great news, Eileen. My thoughts and prayers are with you.
      Looking forward to hearing about that vacation too!
      karen

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      kylez
      Participant

      Eileen, congratulations on getting your first dose of BRAF/MEK (it sounds like you're that far into it, right?). Must be a big relief. Didn't realize the trial would be that intensive appointment-wise.  Great job making all that happen!
      Kyle 

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        Eileen L
        Participant
        Hi Kyle. The trial protocol is very intensive for the first eight weeks then eases up a bit. Missed you at the support group this week! Hope to see you soon. Eileen

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        Eileen L
        Participant
        Hi Kyle. The trial protocol is very intensive for the first eight weeks then eases up a bit. Missed you at the support group this week! Hope to see you soon. Eileen

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        Eileen L
        Participant
        Hi Kyle. The trial protocol is very intensive for the first eight weeks then eases up a bit. Missed you at the support group this week! Hope to see you soon. Eileen

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        Eileen L
        Participant
        P.S. I am out of Kaiser as of July 1!

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        Eileen L
        Participant
        P.S. I am out of Kaiser as of July 1!

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        Eileen L
        Participant
        P.S. I am out of Kaiser as of July 1!

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      kylez
      Participant

      Eileen, congratulations on getting your first dose of BRAF/MEK (it sounds like you're that far into it, right?). Must be a big relief. Didn't realize the trial would be that intensive appointment-wise.  Great job making all that happen!
      Kyle 

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      kylez
      Participant

      Eileen, congratulations on getting your first dose of BRAF/MEK (it sounds like you're that far into it, right?). Must be a big relief. Didn't realize the trial would be that intensive appointment-wise.  Great job making all that happen!
      Kyle 

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      sandman
      Participant

      I have been on BRAF/MEK/GSK since March 7th.  First scan 75% of the cancer is gone!! Make certain to take it exactly as directed, kick your nutrition up a notch and spend lots of time with G-D.  You will do great, I am certain of it. Write me back with any questions and I will help if I can.

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      sandman
      Participant

      I have been on BRAF/MEK/GSK since March 7th.  First scan 75% of the cancer is gone!! Make certain to take it exactly as directed, kick your nutrition up a notch and spend lots of time with G-D.  You will do great, I am certain of it. Write me back with any questions and I will help if I can.

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      sandman
      Participant

      I have been on BRAF/MEK/GSK since March 7th.  First scan 75% of the cancer is gone!! Make certain to take it exactly as directed, kick your nutrition up a notch and spend lots of time with G-D.  You will do great, I am certain of it. Write me back with any questions and I will help if I can.

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      AllyNTAus
      Participant

      Eileen, just offering you good wishes for your trial. The news late last week about the phase 1 results from the GSK BRAF/MEK trial were certainly very encouraging!

      Just to let you know what I am experiencing and hopefully by way of encouragment, I am three weeks into taking Dabrafenib on a compassionate access program (I failed the entry criteria for the BRAF/MEK trial because I had some pneumonitis at the time of screening), and I've had no real side effects apart from a couple of possible SCCs appearing around the place. I had a small palpable node (we think) in my right armpit just before starting Dabrafenib and within a week it had disappeared. A bunch of melanomas on my scalp which were growing and getting quite irritable have flattened and reduced in size. I will not know about my internal nodes (para-aortic, groin) until I get scanned in a couple of months but have everything crossed.

      I also lead an active outdoor lifestyle, and have ramped up the usual sun protection an extra notch, and have had no problems.

      All the best,

      Ally

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      AllyNTAus
      Participant

      Eileen, just offering you good wishes for your trial. The news late last week about the phase 1 results from the GSK BRAF/MEK trial were certainly very encouraging!

      Just to let you know what I am experiencing and hopefully by way of encouragment, I am three weeks into taking Dabrafenib on a compassionate access program (I failed the entry criteria for the BRAF/MEK trial because I had some pneumonitis at the time of screening), and I've had no real side effects apart from a couple of possible SCCs appearing around the place. I had a small palpable node (we think) in my right armpit just before starting Dabrafenib and within a week it had disappeared. A bunch of melanomas on my scalp which were growing and getting quite irritable have flattened and reduced in size. I will not know about my internal nodes (para-aortic, groin) until I get scanned in a couple of months but have everything crossed.

      I also lead an active outdoor lifestyle, and have ramped up the usual sun protection an extra notch, and have had no problems.

      All the best,

      Ally

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      AllyNTAus
      Participant

      Eileen, just offering you good wishes for your trial. The news late last week about the phase 1 results from the GSK BRAF/MEK trial were certainly very encouraging!

      Just to let you know what I am experiencing and hopefully by way of encouragment, I am three weeks into taking Dabrafenib on a compassionate access program (I failed the entry criteria for the BRAF/MEK trial because I had some pneumonitis at the time of screening), and I've had no real side effects apart from a couple of possible SCCs appearing around the place. I had a small palpable node (we think) in my right armpit just before starting Dabrafenib and within a week it had disappeared. A bunch of melanomas on my scalp which were growing and getting quite irritable have flattened and reduced in size. I will not know about my internal nodes (para-aortic, groin) until I get scanned in a couple of months but have everything crossed.

      I also lead an active outdoor lifestyle, and have ramped up the usual sun protection an extra notch, and have had no problems.

      All the best,

      Ally

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Viewing 17 reply threads
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