LDH elevated
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LDH elevated

› Forums › General Melanoma Community › LDH elevated

  • Post
    • July 28, 2016 at 6:02 pm
    JC
    Participant

    I'm a stage 1 from 5 years ago.  had an annual physical the other day and LDH is slightly elevated 252 U/L.  I'm not sure if i should be worried or take any further action because of this with regard to the risk of it being melanoma as the cause.

Viewing 14 reply threads
  • Replies
      • July 28, 2016 at 6:17 pm
      Patrisa
      Participant

      Ldh is sooo much more indicative of other issues than melanoma… It's not even a marker for melanoma, though it can be elevated sometimes because of it…

      the probability that the elevation is not mel related is much greater than that it is…

      Keep calm until u know more!!

      love, 

      Patrisa

        • July 28, 2016 at 6:35 pm
        JC
        Participant

        thanks. the problem is i don't know how to go about knowing more.  i'm not sure what I or doctor would do to investigate this any further.  it's the highest it's ever been for me:

        August 2012    184

        February 2013    172

        July 2013     177

        February 2014    199

        May 2014   196

        July 2014  179

        February 2015   175

        July 2015    192

        February 2016    137

        Now    252

        • July 29, 2016 at 4:50 pm
        Gene_S
        Participant

        that is not a high number.  Mine was over 1200 and is now down in the Normal range since treatment success as I had melanoma in my liver and lungs.

        • July 29, 2016 at 4:50 pm
        Gene_S
        Participant

        that is not a high number.  Mine was over 1200 and is now down in the Normal range since treatment success as I had melanoma in my liver and lungs.

        • July 29, 2016 at 4:50 pm
        Gene_S
        Participant

        that is not a high number.  Mine was over 1200 and is now down in the Normal range since treatment success as I had melanoma in my liver and lungs.

        • July 28, 2016 at 6:35 pm
        JC
        Participant

        thanks. the problem is i don't know how to go about knowing more.  i'm not sure what I or doctor would do to investigate this any further.  it's the highest it's ever been for me:

        August 2012    184

        February 2013    172

        July 2013     177

        February 2014    199

        May 2014   196

        July 2014  179

        February 2015   175

        July 2015    192

        February 2016    137

        Now    252

        • July 28, 2016 at 6:35 pm
        JC
        Participant

        thanks. the problem is i don't know how to go about knowing more.  i'm not sure what I or doctor would do to investigate this any further.  it's the highest it's ever been for me:

        August 2012    184

        February 2013    172

        July 2013     177

        February 2014    199

        May 2014   196

        July 2014  179

        February 2015   175

        July 2015    192

        February 2016    137

        Now    252

      • July 28, 2016 at 6:17 pm
      Patrisa
      Participant

      Ldh is sooo much more indicative of other issues than melanoma… It's not even a marker for melanoma, though it can be elevated sometimes because of it…

      the probability that the elevation is not mel related is much greater than that it is…

      Keep calm until u know more!!

      love, 

      Patrisa

      • July 28, 2016 at 6:17 pm
      Patrisa
      Participant

      Ldh is sooo much more indicative of other issues than melanoma… It's not even a marker for melanoma, though it can be elevated sometimes because of it…

      the probability that the elevation is not mel related is much greater than that it is…

      Keep calm until u know more!!

      love, 

      Patrisa

      • July 28, 2016 at 6:49 pm
      Patrisa
      Participant

      Well, you can go again to the doctors in a couple of weeks and take another ldh test to see if drops down or not.. And take it from there…

      Ldh can be elevated from strenuous excercise, alcohol, some medicine etc… So take it easy in a couple of weeks and do another test..

      and take it from there… 

      If mel was never a part of your life, you would never be this worried about this elevation, but yeah, i get where are you coming from, i would ask the same questions as you…

      Other that that, i can't say really what else you can do, your insurance system (usa) is soooo difficult to understand (ours is more like canadian), so don't know if they are willing to pay for something else…

      You can also get your blood tested for S100 marker, it can also be elevated because of melanoma ( in my country they test it regularely in mel patients)… 

      Love, 

      Patrisa

      • July 28, 2016 at 6:49 pm
      Patrisa
      Participant

      Well, you can go again to the doctors in a couple of weeks and take another ldh test to see if drops down or not.. And take it from there…

      Ldh can be elevated from strenuous excercise, alcohol, some medicine etc… So take it easy in a couple of weeks and do another test..

      and take it from there… 

      If mel was never a part of your life, you would never be this worried about this elevation, but yeah, i get where are you coming from, i would ask the same questions as you…

      Other that that, i can't say really what else you can do, your insurance system (usa) is soooo difficult to understand (ours is more like canadian), so don't know if they are willing to pay for something else…

      You can also get your blood tested for S100 marker, it can also be elevated because of melanoma ( in my country they test it regularely in mel patients)… 

      Love, 

      Patrisa

      • July 28, 2016 at 6:49 pm
      Patrisa
      Participant

      Well, you can go again to the doctors in a couple of weeks and take another ldh test to see if drops down or not.. And take it from there…

      Ldh can be elevated from strenuous excercise, alcohol, some medicine etc… So take it easy in a couple of weeks and do another test..

      and take it from there… 

      If mel was never a part of your life, you would never be this worried about this elevation, but yeah, i get where are you coming from, i would ask the same questions as you…

      Other that that, i can't say really what else you can do, your insurance system (usa) is soooo difficult to understand (ours is more like canadian), so don't know if they are willing to pay for something else…

      You can also get your blood tested for S100 marker, it can also be elevated because of melanoma ( in my country they test it regularely in mel patients)… 

      Love, 

      Patrisa

      • July 28, 2016 at 7:43 pm
      RaquelP
      Participant

      It can go up for a number of reasons. Are any other enzymes elevated with it? All sorts of condtions can cause it to rise…mono, muscle strain, gall stones, even random viruses.

        • July 28, 2016 at 7:57 pm
        JC
        Participant

        no, nothing else elevated

        • July 28, 2016 at 9:51 pm
        Toby0987
        Participant

        I was in the high 100s and then jumped to 232. My oncologist said no big deal (I'm 3b)

        • July 28, 2016 at 9:51 pm
        Toby0987
        Participant

        I was in the high 100s and then jumped to 232. My oncologist said no big deal (I'm 3b)

        • July 28, 2016 at 9:51 pm
        Toby0987
        Participant

        I was in the high 100s and then jumped to 232. My oncologist said no big deal (I'm 3b)

        • July 28, 2016 at 7:57 pm
        JC
        Participant

        no, nothing else elevated

        • July 28, 2016 at 7:57 pm
        JC
        Participant

        no, nothing else elevated

      • July 28, 2016 at 7:43 pm
      RaquelP
      Participant

      It can go up for a number of reasons. Are any other enzymes elevated with it? All sorts of condtions can cause it to rise…mono, muscle strain, gall stones, even random viruses.

      • July 28, 2016 at 7:43 pm
      RaquelP
      Participant

      It can go up for a number of reasons. Are any other enzymes elevated with it? All sorts of condtions can cause it to rise…mono, muscle strain, gall stones, even random viruses.

      • July 28, 2016 at 11:45 pm
      Polymath
      Participant

      according to my chart, the standard range is 94-250 U/L so your 252 is just at the upper range of normal.  Nothing to panic about at this point, continue to monitor.  As has been noted, LDH can be temporarily elevated for a number of reasons besides tumor burden.

      • July 28, 2016 at 11:45 pm
      Polymath
      Participant

      according to my chart, the standard range is 94-250 U/L so your 252 is just at the upper range of normal.  Nothing to panic about at this point, continue to monitor.  As has been noted, LDH can be temporarily elevated for a number of reasons besides tumor burden.

      • July 28, 2016 at 11:45 pm
      Polymath
      Participant

      according to my chart, the standard range is 94-250 U/L so your 252 is just at the upper range of normal.  Nothing to panic about at this point, continue to monitor.  As has been noted, LDH can be temporarily elevated for a number of reasons besides tumor burden.

      • July 29, 2016 at 2:03 am
      Cathy M
      Participant
      252 high normal is our lab range too. LDH is not a reliable tumor marker but we always watch it too. In 2013 when my husband learned of his stage 4 metastatic melanoma his LDH had gone up in to the 600’s. As treatments progressed it dropped down into a normal range. But as of last Thursday his PET scan came back with hypermetabolic existing larger nodules and even new nodules with a normal range LDH of 232. So yes, we watch the LDH levels but definitely don’t rely on this to determine if the melanoma is actively spreading or not. Gpod luck with your battle!!
        • August 30, 2016 at 9:47 am
        JC
        Participant

        I had it rechecked (a month later) and it's now 220.  it's still on the high end and higher than my previous results, but slightly lower than the last result.  i don't know what to think about this, could a slight elevation be a sign of an early spread?  

        • August 30, 2016 at 9:47 am
        JC
        Participant

        I had it rechecked (a month later) and it's now 220.  it's still on the high end and higher than my previous results, but slightly lower than the last result.  i don't know what to think about this, could a slight elevation be a sign of an early spread?  

        • August 30, 2016 at 9:47 am
        JC
        Participant

        I had it rechecked (a month later) and it's now 220.  it's still on the high end and higher than my previous results, but slightly lower than the last result.  i don't know what to think about this, could a slight elevation be a sign of an early spread?  

      • July 29, 2016 at 2:03 am
      Cathy M
      Participant
      252 high normal is our lab range too. LDH is not a reliable tumor marker but we always watch it too. In 2013 when my husband learned of his stage 4 metastatic melanoma his LDH had gone up in to the 600’s. As treatments progressed it dropped down into a normal range. But as of last Thursday his PET scan came back with hypermetabolic existing larger nodules and even new nodules with a normal range LDH of 232. So yes, we watch the LDH levels but definitely don’t rely on this to determine if the melanoma is actively spreading or not. Gpod luck with your battle!!
      • July 29, 2016 at 2:03 am
      Cathy M
      Participant
      252 high normal is our lab range too. LDH is not a reliable tumor marker but we always watch it too. In 2013 when my husband learned of his stage 4 metastatic melanoma his LDH had gone up in to the 600’s. As treatments progressed it dropped down into a normal range. But as of last Thursday his PET scan came back with hypermetabolic existing larger nodules and even new nodules with a normal range LDH of 232. So yes, we watch the LDH levels but definitely don’t rely on this to determine if the melanoma is actively spreading or not. Gpod luck with your battle!!
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