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LDH concerns

Forums General Melanoma Community LDH concerns

  • Post
    mrbill16323
    Participant
    Hello all. After discovery of Stage IIIC melanoma on top of my head, had Wide Excision surgery and reconstruction. Nineteen lymph nodes were also biopsied with zero sign of disease.  Started on Keytruda and I’m at cycle #11 this week. Tolerating it very well. My PET scan three weeks ago showed no concerns. I just had my blood tests done for my oncology doc appt and Keytruda infusion later this week. My LDH has been tracking in normal range except for one data point on 3/2/2021. – then 294. Then normal range again for the next six weeks (218, 222). Most recent is 324 this week. I’ll be discussing this with my oncologist this week Thursday. It’s just weighing on my mind. All other blood measures are in normal range. Just live life to its fullest and see what will come. Thanks for listening my friends.

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  • Replies
      CindyJ
      Participant
      I’m no expert but as someone who’s been riding my mother’s oncologist for four years regarding her LDH number I can offer the following. My mom’s number has spiked several times close to your number. Her doctor always has to remind me that the LDH is not the best tumor marker, but is all they have for melanoma. Lots of things can make the number spike… an infection, an injury somewhere in/on the body, even how the blood tube was handled before testing. Since you just had a clean PET, I wouldn’t be concerned with a number that one testing is showing. Hope this helps ease the mind a bit. Best wishes!

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        mrbill16323
        Participant
        Thank you Cindy. I appreciate your advice.

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      Beth
      Participant
      I just had this exact conversation with my oncologist today because I’ve had similar results.  I had a high in February of 268 then back to normal until it jumped to 274 this week.  I had scans 4 weeks ago that did not indicate anything to be concerned about.  My doctor reminded me that this a very non-specific test and as Cindy said can indicate inflammation anywhere in the body.  She was not concerned about it but we agreed to have new labs done in 2 weeks to make sure it’s trending in the right direction and for my own peace of mind.

      Best of luck!

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