› Forums › General Melanoma Community › It’s ANTI- PD1 guys…..(melanoma preventive drug)
- This topic has 78 replies, 11 voices, and was last updated 11 years, 9 months ago by
caseym.
- Post
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- August 23, 2012 at 4:44 pm
This is the drug that Dr. Bedikian told Wayne they hoped would be available for Wayne in a few months ! Just found out and letting you know !
This is the drug that Dr. Bedikian told Wayne they hoped would be available for Wayne in a few months ! Just found out and letting you know !
- Replies
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- August 24, 2012 at 3:10 am
My Dr. Has also told me that anti PD1 should be coming out in the next few months!I have one spot left behind my knee. We are waiting 3 months to see if the Ippi and radiation worked. It is sitting on a nerve so removing it is not a good option.
Nancy
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- August 24, 2012 at 3:10 am
My Dr. Has also told me that anti PD1 should be coming out in the next few months!I have one spot left behind my knee. We are waiting 3 months to see if the Ippi and radiation worked. It is sitting on a nerve so removing it is not a good option.
Nancy
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- August 24, 2012 at 3:10 am
My Dr. Has also told me that anti PD1 should be coming out in the next few months!I have one spot left behind my knee. We are waiting 3 months to see if the Ippi and radiation worked. It is sitting on a nerve so removing it is not a good option.
Nancy
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- August 24, 2012 at 5:12 pm
Hi,
When you say anti-pd1 drug is (available) coming,are you talking about a clinical trial???? If so,who is the sponsor???
Thanks for answering my question.
Amy
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- August 25, 2012 at 7:24 am
Anti-pd1 is only in clinical trials. BMS is trying to fast track their version to phase 3 which has been in trials for a few years now. Merck's version began around the 1st of this year and is still years away from FDA approval. With the successes reported at ASCO this year of the BMS drug, and the early reports of success with Merck's, I believe the industry will speed these trials along. Watch for combo trials that are starting up. After failed biochemo and failed pi3k, anti-pd1 is working for me with minimal side effects. 40% tumor reduction at 12 week scans! Had my 24 week pet/ct yesterday and waiting for results. For those whose tumors express the pd ligand, this is a game changer. I was diagnosed stage 4 in March of 2011, braf negative, nras q61+.
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- August 25, 2012 at 7:24 am
Anti-pd1 is only in clinical trials. BMS is trying to fast track their version to phase 3 which has been in trials for a few years now. Merck's version began around the 1st of this year and is still years away from FDA approval. With the successes reported at ASCO this year of the BMS drug, and the early reports of success with Merck's, I believe the industry will speed these trials along. Watch for combo trials that are starting up. After failed biochemo and failed pi3k, anti-pd1 is working for me with minimal side effects. 40% tumor reduction at 12 week scans! Had my 24 week pet/ct yesterday and waiting for results. For those whose tumors express the pd ligand, this is a game changer. I was diagnosed stage 4 in March of 2011, braf negative, nras q61+.
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- August 25, 2012 at 4:08 pm
Robert,
Thank you for the explanation. How wonderful for you to get a response so quickly. What are your side effects?
Please post the results of your scans from yesterday. You gives us all hope.
I will pray for clear scans for you.
God Bless you
Amy
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- August 25, 2012 at 4:08 pm
Robert,
Thank you for the explanation. How wonderful for you to get a response so quickly. What are your side effects?
Please post the results of your scans from yesterday. You gives us all hope.
I will pray for clear scans for you.
God Bless you
Amy
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- August 26, 2012 at 5:50 pm
Hello Robert,
I am so that I offended you that I do not have a profile done.
I am 80 years old and I do not know how to do the computer well. I could not figure out how to do the profile, etc. My granddaughter has melanoma.
It seems to me that I offered you my prayers but it appears that knowing my profile is more important to you.Since you have a rule about sharing with anonmous posts, please do not share any information with me. That seems very important ot you.
I will be more careful to post next time (if there is a next time). I was just offering my prayers to warriors of this terrible disease.
Do other members of the board feel the same way as Robert??? Please post your response so I know not to post any longer.
Thanks so much for your time to read my post and reply. I apologize to everyone.
Amy
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- August 26, 2012 at 5:50 pm
Hello Robert,
I am so that I offended you that I do not have a profile done.
I am 80 years old and I do not know how to do the computer well. I could not figure out how to do the profile, etc. My granddaughter has melanoma.
It seems to me that I offered you my prayers but it appears that knowing my profile is more important to you.Since you have a rule about sharing with anonmous posts, please do not share any information with me. That seems very important ot you.
I will be more careful to post next time (if there is a next time). I was just offering my prayers to warriors of this terrible disease.
Do other members of the board feel the same way as Robert??? Please post your response so I know not to post any longer.
Thanks so much for your time to read my post and reply. I apologize to everyone.
Amy
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- August 26, 2012 at 6:15 pm
Please re read my post as you misunderstood it. I am not offended by your post and I welcome anyones prayers for me and the rest on this forum. What I said was I don't like to share posts with those that have not created a profile. I then asked questions about your situation in order to provide relevant comments. This disease is a very personal and intimate journey and if someone is asking specific questions about my disease I would appreciate knowing who I am speaking with, this is a 2 way street. I know many on this forum with melanoma feel the same way. Please do not stop posting on my account, but you will get much more out of this forum if you get someone to help you create a profile and tell us about your granddaughters case. That way you will receive more specific and targeted support and advice to help you support her. Better yet, is she old enough for a profile of her own? This forum has been a huge support for us in the battle and may be for her as well.
Robert
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- August 26, 2012 at 6:15 pm
Please re read my post as you misunderstood it. I am not offended by your post and I welcome anyones prayers for me and the rest on this forum. What I said was I don't like to share posts with those that have not created a profile. I then asked questions about your situation in order to provide relevant comments. This disease is a very personal and intimate journey and if someone is asking specific questions about my disease I would appreciate knowing who I am speaking with, this is a 2 way street. I know many on this forum with melanoma feel the same way. Please do not stop posting on my account, but you will get much more out of this forum if you get someone to help you create a profile and tell us about your granddaughters case. That way you will receive more specific and targeted support and advice to help you support her. Better yet, is she old enough for a profile of her own? This forum has been a huge support for us in the battle and may be for her as well.
Robert
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- August 26, 2012 at 7:15 pm
Dear Amy,
You’re not annonymous, you’re Amy! How wonderful that you’re here on behalf of your granddaughter.
Robert makes some valid points. We could be of more help if we knew more about your granddaughter’s diagnosis. Maybe someone could help you with your profile. ( my mom is just a bit older than you…I wish she were half as computer-literate as you!)
I have always found “annonymous” off-putting and find it much easier to correspond to a name.
I hope this is helpful…I guarantee that Robert was trying to be of help, and we all appreciate prayers.
Karen
PS. I know sometimes people use annonymous (as I once did) to report/discourage inappropriate postings, but i just don’t find the same intimacy if it’s used regularly. Just my own personal feelings, folks. -
- August 26, 2012 at 7:15 pm
Dear Amy,
You’re not annonymous, you’re Amy! How wonderful that you’re here on behalf of your granddaughter.
Robert makes some valid points. We could be of more help if we knew more about your granddaughter’s diagnosis. Maybe someone could help you with your profile. ( my mom is just a bit older than you…I wish she were half as computer-literate as you!)
I have always found “annonymous” off-putting and find it much easier to correspond to a name.
I hope this is helpful…I guarantee that Robert was trying to be of help, and we all appreciate prayers.
Karen
PS. I know sometimes people use annonymous (as I once did) to report/discourage inappropriate postings, but i just don’t find the same intimacy if it’s used regularly. Just my own personal feelings, folks. -
- August 28, 2012 at 5:50 pm
I agree, but think Amy should get some credit for giving her name at the end of her 'anonymous' post in an attempt to differentiate her post from others. (Such a pity that even after explaining her situation she is still not able to get a reply to her questions though!)
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- August 28, 2012 at 5:50 pm
I agree, but think Amy should get some credit for giving her name at the end of her 'anonymous' post in an attempt to differentiate her post from others. (Such a pity that even after explaining her situation she is still not able to get a reply to her questions though!)
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- August 28, 2012 at 5:50 pm
I agree, but think Amy should get some credit for giving her name at the end of her 'anonymous' post in an attempt to differentiate her post from others. (Such a pity that even after explaining her situation she is still not able to get a reply to her questions though!)
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- August 29, 2012 at 6:09 pm
You mentioned minimal side effects and Amy asked, "What are your side effects? "and "Please post the results of your scans from yesterday" You then said
"I don't like to share posts with those that have not created a profile. I then asked questions about your situation in order to provide relevant comments. This disease is a very personal and intimate journey and if someone is asking specific questions about my disease I would appreciate knowing who I am speaking with, this is a 2 way street. I know many on this forum with melanoma feel the same way. Please do not stop posting on my account, but you will get much more out of this forum if you get someone to help you create a profile and tell us about your granddaughters case. That way you will receive more specific and targeted support and advice to help you support her. Better yet, is she old enough for a profile of her own? This forum has been a huge support for us in the battle and may be for her as well."
It is your choice to share with whomever you chose, just as it is my choice to feel pity for an elderly grandma who searches the internet for information to help a feared for grandchild A 'child' who may be in dire need of help. (Perhaps even in too much pain to post on the internet, or off in another state with grandma surviving on snippets of information.. all of it worrisome.) Pity is a strong emotion.
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- August 29, 2012 at 6:09 pm
You mentioned minimal side effects and Amy asked, "What are your side effects? "and "Please post the results of your scans from yesterday" You then said
"I don't like to share posts with those that have not created a profile. I then asked questions about your situation in order to provide relevant comments. This disease is a very personal and intimate journey and if someone is asking specific questions about my disease I would appreciate knowing who I am speaking with, this is a 2 way street. I know many on this forum with melanoma feel the same way. Please do not stop posting on my account, but you will get much more out of this forum if you get someone to help you create a profile and tell us about your granddaughters case. That way you will receive more specific and targeted support and advice to help you support her. Better yet, is she old enough for a profile of her own? This forum has been a huge support for us in the battle and may be for her as well."
It is your choice to share with whomever you chose, just as it is my choice to feel pity for an elderly grandma who searches the internet for information to help a feared for grandchild A 'child' who may be in dire need of help. (Perhaps even in too much pain to post on the internet, or off in another state with grandma surviving on snippets of information.. all of it worrisome.) Pity is a strong emotion.
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- August 29, 2012 at 6:09 pm
You mentioned minimal side effects and Amy asked, "What are your side effects? "and "Please post the results of your scans from yesterday" You then said
"I don't like to share posts with those that have not created a profile. I then asked questions about your situation in order to provide relevant comments. This disease is a very personal and intimate journey and if someone is asking specific questions about my disease I would appreciate knowing who I am speaking with, this is a 2 way street. I know many on this forum with melanoma feel the same way. Please do not stop posting on my account, but you will get much more out of this forum if you get someone to help you create a profile and tell us about your granddaughters case. That way you will receive more specific and targeted support and advice to help you support her. Better yet, is she old enough for a profile of her own? This forum has been a huge support for us in the battle and may be for her as well."
It is your choice to share with whomever you chose, just as it is my choice to feel pity for an elderly grandma who searches the internet for information to help a feared for grandchild A 'child' who may be in dire need of help. (Perhaps even in too much pain to post on the internet, or off in another state with grandma surviving on snippets of information.. all of it worrisome.) Pity is a strong emotion.
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- August 26, 2012 at 7:15 pm
Dear Amy,
You’re not annonymous, you’re Amy! How wonderful that you’re here on behalf of your granddaughter.
Robert makes some valid points. We could be of more help if we knew more about your granddaughter’s diagnosis. Maybe someone could help you with your profile. ( my mom is just a bit older than you…I wish she were half as computer-literate as you!)
I have always found “annonymous” off-putting and find it much easier to correspond to a name.
I hope this is helpful…I guarantee that Robert was trying to be of help, and we all appreciate prayers.
Karen
PS. I know sometimes people use annonymous (as I once did) to report/discourage inappropriate postings, but i just don’t find the same intimacy if it’s used regularly. Just my own personal feelings, folks. -
- August 26, 2012 at 6:15 pm
Please re read my post as you misunderstood it. I am not offended by your post and I welcome anyones prayers for me and the rest on this forum. What I said was I don't like to share posts with those that have not created a profile. I then asked questions about your situation in order to provide relevant comments. This disease is a very personal and intimate journey and if someone is asking specific questions about my disease I would appreciate knowing who I am speaking with, this is a 2 way street. I know many on this forum with melanoma feel the same way. Please do not stop posting on my account, but you will get much more out of this forum if you get someone to help you create a profile and tell us about your granddaughters case. That way you will receive more specific and targeted support and advice to help you support her. Better yet, is she old enough for a profile of her own? This forum has been a huge support for us in the battle and may be for her as well.
Robert
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- August 26, 2012 at 5:50 pm
Hello Robert,
I am so that I offended you that I do not have a profile done.
I am 80 years old and I do not know how to do the computer well. I could not figure out how to do the profile, etc. My granddaughter has melanoma.
It seems to me that I offered you my prayers but it appears that knowing my profile is more important to you.Since you have a rule about sharing with anonmous posts, please do not share any information with me. That seems very important ot you.
I will be more careful to post next time (if there is a next time). I was just offering my prayers to warriors of this terrible disease.
Do other members of the board feel the same way as Robert??? Please post your response so I know not to post any longer.
Thanks so much for your time to read my post and reply. I apologize to everyone.
Amy
-
- August 25, 2012 at 4:08 pm
Robert,
Thank you for the explanation. How wonderful for you to get a response so quickly. What are your side effects?
Please post the results of your scans from yesterday. You gives us all hope.
I will pray for clear scans for you.
God Bless you
Amy
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- August 26, 2012 at 10:01 pm
Dr. B told us this drug would be ready for people who had NO MELENOMA in a couple of months ! 🙂 Wayne has one small spot on this leg above his knee and Dr. B is waiting to see if this spot is just stubborn and taking a little longer as ALL of his other spots (8) were gone in 7 weeks. Liver, lungs, sternum, spine. He will do a biopsy in Oct./Nov. if it's still there to confirm Melly and then do surgery to remove it, making Wayne a candidate for this drug ! That's what we were told. 🙂 We did ask his assistant for the name of the drug a second time and thought she may have gotten B and D mixed up, but we're still not sure. Will know more on Sept. visit ! You know how that second hand info is……..but he seemed to think it would be ready for Wayne by end of the year at the latest. ????? 🙂
Nancy (devoted wife of 3 X Warrior Wayne)
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- August 26, 2012 at 10:01 pm
Dr. B told us this drug would be ready for people who had NO MELENOMA in a couple of months ! 🙂 Wayne has one small spot on this leg above his knee and Dr. B is waiting to see if this spot is just stubborn and taking a little longer as ALL of his other spots (8) were gone in 7 weeks. Liver, lungs, sternum, spine. He will do a biopsy in Oct./Nov. if it's still there to confirm Melly and then do surgery to remove it, making Wayne a candidate for this drug ! That's what we were told. 🙂 We did ask his assistant for the name of the drug a second time and thought she may have gotten B and D mixed up, but we're still not sure. Will know more on Sept. visit ! You know how that second hand info is……..but he seemed to think it would be ready for Wayne by end of the year at the latest. ????? 🙂
Nancy (devoted wife of 3 X Warrior Wayne)
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- August 26, 2012 at 11:06 pm
Nancy,
Please try and get a clarification on this from your Dr. and post what you find out as so many like NYKaren are down to limited or 0 options and are just waiting for news on PD-1. For me, information like pd-1 coming gave me hope and got me through really bad times. I felt like a kid on Christmas the day I was accepted into the trial. All any of us ask for is a glimmer of hope to keep us going until the next discovery that may lead to a cure for the beast. Thanks for sharing !
Thanks,
Robert
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- August 26, 2012 at 11:06 pm
Nancy,
Please try and get a clarification on this from your Dr. and post what you find out as so many like NYKaren are down to limited or 0 options and are just waiting for news on PD-1. For me, information like pd-1 coming gave me hope and got me through really bad times. I felt like a kid on Christmas the day I was accepted into the trial. All any of us ask for is a glimmer of hope to keep us going until the next discovery that may lead to a cure for the beast. Thanks for sharing !
Thanks,
Robert
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- August 26, 2012 at 11:06 pm
Nancy,
Please try and get a clarification on this from your Dr. and post what you find out as so many like NYKaren are down to limited or 0 options and are just waiting for news on PD-1. For me, information like pd-1 coming gave me hope and got me through really bad times. I felt like a kid on Christmas the day I was accepted into the trial. All any of us ask for is a glimmer of hope to keep us going until the next discovery that may lead to a cure for the beast. Thanks for sharing !
Thanks,
Robert
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- September 2, 2012 at 6:17 am
I know from speaking with BMS on the phone a couple months ago that their Anti PD-1 will not be approved for at least another year and half to 2 years… they should know! No one should hang their hopes on any drug that is still in phase one trials waiting to get it approved. I have been doing it since fall 2010 and I have been NED for 2 years 5 months. I have next treatment on Sept 5 and then I will only have 2 treatments left in the trial. I am in week 101 of the trial now.
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- September 2, 2012 at 6:17 am
I know from speaking with BMS on the phone a couple months ago that their Anti PD-1 will not be approved for at least another year and half to 2 years… they should know! No one should hang their hopes on any drug that is still in phase one trials waiting to get it approved. I have been doing it since fall 2010 and I have been NED for 2 years 5 months. I have next treatment on Sept 5 and then I will only have 2 treatments left in the trial. I am in week 101 of the trial now.
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- September 2, 2012 at 6:17 am
I know from speaking with BMS on the phone a couple months ago that their Anti PD-1 will not be approved for at least another year and half to 2 years… they should know! No one should hang their hopes on any drug that is still in phase one trials waiting to get it approved. I have been doing it since fall 2010 and I have been NED for 2 years 5 months. I have next treatment on Sept 5 and then I will only have 2 treatments left in the trial. I am in week 101 of the trial now.
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- August 26, 2012 at 10:01 pm
Dr. B told us this drug would be ready for people who had NO MELENOMA in a couple of months ! 🙂 Wayne has one small spot on this leg above his knee and Dr. B is waiting to see if this spot is just stubborn and taking a little longer as ALL of his other spots (8) were gone in 7 weeks. Liver, lungs, sternum, spine. He will do a biopsy in Oct./Nov. if it's still there to confirm Melly and then do surgery to remove it, making Wayne a candidate for this drug ! That's what we were told. 🙂 We did ask his assistant for the name of the drug a second time and thought she may have gotten B and D mixed up, but we're still not sure. Will know more on Sept. visit ! You know how that second hand info is……..but he seemed to think it would be ready for Wayne by end of the year at the latest. ????? 🙂
Nancy (devoted wife of 3 X Warrior Wayne)
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- August 26, 2012 at 11:00 pm
Karen,
I have been told that there are combo trials starting up pretty soon that will include anti-pd-1 and other drugs. I've also heard that anti-pd-1 may be approved fairly soon for other cancer types and be available off label for melanoma. Not sure why, buyt maybe it's been in trials for other cancers longer?? Maybe that is what Dr. B at MD Anderson is talking about? Have you or your Dr. tried reaching out to BMS or Merck and asking for a compassionate use?
Robert
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- August 26, 2012 at 11:00 pm
Karen,
I have been told that there are combo trials starting up pretty soon that will include anti-pd-1 and other drugs. I've also heard that anti-pd-1 may be approved fairly soon for other cancer types and be available off label for melanoma. Not sure why, buyt maybe it's been in trials for other cancers longer?? Maybe that is what Dr. B at MD Anderson is talking about? Have you or your Dr. tried reaching out to BMS or Merck and asking for a compassionate use?
Robert
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- August 27, 2012 at 1:22 am
Wayne said he would write Dr. B's assistant again this week to verify. He is saying it's a PREVENTIVE MED – and that's why you have to be cancer free (NED) to take it. We had a lot going on at this trip finding out about the spot and staying over and, and, and…..so we were very focused on what was going on then, and what we were going to do – surgery – no surgery – wait – see etc., so we were not paying close enough attention. I should have written it down as I take notes while Wayne is with Doc.
We'll find out…..give us a few days.
I know this and all info it vital to everyone fighting this nasty beast !
Nancy (devoted wife of 3 X Warrior Wayne )
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- August 27, 2012 at 1:22 am
Wayne said he would write Dr. B's assistant again this week to verify. He is saying it's a PREVENTIVE MED – and that's why you have to be cancer free (NED) to take it. We had a lot going on at this trip finding out about the spot and staying over and, and, and…..so we were very focused on what was going on then, and what we were going to do – surgery – no surgery – wait – see etc., so we were not paying close enough attention. I should have written it down as I take notes while Wayne is with Doc.
We'll find out…..give us a few days.
I know this and all info it vital to everyone fighting this nasty beast !
Nancy (devoted wife of 3 X Warrior Wayne )
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- August 27, 2012 at 1:22 am
Wayne said he would write Dr. B's assistant again this week to verify. He is saying it's a PREVENTIVE MED – and that's why you have to be cancer free (NED) to take it. We had a lot going on at this trip finding out about the spot and staying over and, and, and…..so we were very focused on what was going on then, and what we were going to do – surgery – no surgery – wait – see etc., so we were not paying close enough attention. I should have written it down as I take notes while Wayne is with Doc.
We'll find out…..give us a few days.
I know this and all info it vital to everyone fighting this nasty beast !
Nancy (devoted wife of 3 X Warrior Wayne )
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- September 2, 2012 at 6:25 am
I am in this BMS-936558 trial…Monoclonal Antibody Therapy and Vaccine Therapy in Treating Patients With Stage IIIC or IV Melanoma That Has Been Removed By Surgery also titled-
Phase I Study of Anti-PD-1 Human Monoclonal Antibody MDX-1106 and Vaccine Therapy Comprising gp100:209-217(210M) Peptide, MART-1:26-35(27L) Peptide, gp100:280-288(288V) Peptide, NY-ESO-1 Peptide, and Montanide ISA 51 VG in Patients With Resected Stage IIIC or IV MelanomaI had surgery then started the trial….this is exactly the same treatment as those without being NED, except my trial started a couple weeks before the sister trial at Moffitt. At this time Moffitt is the only center using it on NED patients.When BMS gets the anti pd 1 approved, it will be for all melanoma patients…not only for the NED patients. The person I spoke with did mention it might be approved for kidney cancer before its approved for melanoma, but that was as yet uncertain. -
- September 2, 2012 at 6:25 am
I am in this BMS-936558 trial…Monoclonal Antibody Therapy and Vaccine Therapy in Treating Patients With Stage IIIC or IV Melanoma That Has Been Removed By Surgery also titled-
Phase I Study of Anti-PD-1 Human Monoclonal Antibody MDX-1106 and Vaccine Therapy Comprising gp100:209-217(210M) Peptide, MART-1:26-35(27L) Peptide, gp100:280-288(288V) Peptide, NY-ESO-1 Peptide, and Montanide ISA 51 VG in Patients With Resected Stage IIIC or IV MelanomaI had surgery then started the trial….this is exactly the same treatment as those without being NED, except my trial started a couple weeks before the sister trial at Moffitt. At this time Moffitt is the only center using it on NED patients.When BMS gets the anti pd 1 approved, it will be for all melanoma patients…not only for the NED patients. The person I spoke with did mention it might be approved for kidney cancer before its approved for melanoma, but that was as yet uncertain. -
- September 2, 2012 at 6:25 am
I am in this BMS-936558 trial…Monoclonal Antibody Therapy and Vaccine Therapy in Treating Patients With Stage IIIC or IV Melanoma That Has Been Removed By Surgery also titled-
Phase I Study of Anti-PD-1 Human Monoclonal Antibody MDX-1106 and Vaccine Therapy Comprising gp100:209-217(210M) Peptide, MART-1:26-35(27L) Peptide, gp100:280-288(288V) Peptide, NY-ESO-1 Peptide, and Montanide ISA 51 VG in Patients With Resected Stage IIIC or IV MelanomaI had surgery then started the trial….this is exactly the same treatment as those without being NED, except my trial started a couple weeks before the sister trial at Moffitt. At this time Moffitt is the only center using it on NED patients.When BMS gets the anti pd 1 approved, it will be for all melanoma patients…not only for the NED patients. The person I spoke with did mention it might be approved for kidney cancer before its approved for melanoma, but that was as yet uncertain. -
- August 29, 2012 at 12:20 am
Karen,
This is a "different" antipd1 by ammipline (guessing on the spelling) that is offerered in Pineville NC. I only know of one person on this trial and last I heard he is not doing well (at least he has lost like 60 pounds). Pineville is about 30 min from Charlotte NC. I don't know anything about this but if you want I can find a link for you.
linda
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- August 29, 2012 at 12:20 am
Karen,
This is a "different" antipd1 by ammipline (guessing on the spelling) that is offerered in Pineville NC. I only know of one person on this trial and last I heard he is not doing well (at least he has lost like 60 pounds). Pineville is about 30 min from Charlotte NC. I don't know anything about this but if you want I can find a link for you.
linda
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- August 29, 2012 at 12:20 am
Karen,
This is a "different" antipd1 by ammipline (guessing on the spelling) that is offerered in Pineville NC. I only know of one person on this trial and last I heard he is not doing well (at least he has lost like 60 pounds). Pineville is about 30 min from Charlotte NC. I don't know anything about this but if you want I can find a link for you.
linda
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- August 29, 2012 at 8:55 pm
I think that this is the trial that you are talking about:
http://clinicaltrials.gov/ct2/show/NCT01352884?term=nct+01352884&rank=1
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- August 29, 2012 at 8:55 pm
I think that this is the trial that you are talking about:
http://clinicaltrials.gov/ct2/show/NCT01352884?term=nct+01352884&rank=1
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- August 29, 2012 at 8:55 pm
I think that this is the trial that you are talking about:
http://clinicaltrials.gov/ct2/show/NCT01352884?term=nct+01352884&rank=1
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- August 26, 2012 at 11:00 pm
Karen,
I have been told that there are combo trials starting up pretty soon that will include anti-pd-1 and other drugs. I've also heard that anti-pd-1 may be approved fairly soon for other cancer types and be available off label for melanoma. Not sure why, buyt maybe it's been in trials for other cancers longer?? Maybe that is what Dr. B at MD Anderson is talking about? Have you or your Dr. tried reaching out to BMS or Merck and asking for a compassionate use?
Robert
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- August 25, 2012 at 7:24 am
Anti-pd1 is only in clinical trials. BMS is trying to fast track their version to phase 3 which has been in trials for a few years now. Merck's version began around the 1st of this year and is still years away from FDA approval. With the successes reported at ASCO this year of the BMS drug, and the early reports of success with Merck's, I believe the industry will speed these trials along. Watch for combo trials that are starting up. After failed biochemo and failed pi3k, anti-pd1 is working for me with minimal side effects. 40% tumor reduction at 12 week scans! Had my 24 week pet/ct yesterday and waiting for results. For those whose tumors express the pd ligand, this is a game changer. I was diagnosed stage 4 in March of 2011, braf negative, nras q61+.
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- May 5, 2013 at 10:33 pm
Hello. I am Becky C. from Jackson, Ms. I am also waiting to hear about the anti-pd1 trial. I met with Dr. Hu from MDA about two weeks ago. I was told it was coming up in May. Everything I have read talks about great results. Keeping my fingers crossed.
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- May 5, 2013 at 10:33 pm
Hello. I am Becky C. from Jackson, Ms. I am also waiting to hear about the anti-pd1 trial. I met with Dr. Hu from MDA about two weeks ago. I was told it was coming up in May. Everything I have read talks about great results. Keeping my fingers crossed.
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- May 5, 2013 at 10:33 pm
Hello. I am Becky C. from Jackson, Ms. I am also waiting to hear about the anti-pd1 trial. I met with Dr. Hu from MDA about two weeks ago. I was told it was coming up in May. Everything I have read talks about great results. Keeping my fingers crossed.
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- May 13, 2013 at 1:41 am
Hi Everyone,
My mum is number 3 on the second round of the PD1 clinical trial in Australia.
I was wondering if anyone has any information about being on this trial, sideaffects and success rate?
I want to do as much as I can for my mum any help would be great.
Thank you Casey
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- May 13, 2013 at 1:41 am
Hi Everyone,
My mum is number 3 on the second round of the PD1 clinical trial in Australia.
I was wondering if anyone has any information about being on this trial, sideaffects and success rate?
I want to do as much as I can for my mum any help would be great.
Thank you Casey
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- May 13, 2013 at 1:41 am
Hi Everyone,
My mum is number 3 on the second round of the PD1 clinical trial in Australia.
I was wondering if anyone has any information about being on this trial, sideaffects and success rate?
I want to do as much as I can for my mum any help would be great.
Thank you Casey
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