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Ipilubimab question

Forums General Melanoma Community Ipilubimab question

  • Post
    ljhncj12345
    Participant

      I read this board frquently but seldom post anything.   I Was just wondering if anyone out there has had a good result after ony 3 ipi treatments.  My husband has had a rare side effect that put him in acute kidney failure. Steroids have brought kidney function back to normal but now they will not do the fourth treatment. Scans on monday and we fid out where we are on Wednesday.

      I read this board frquently but seldom post anything.   I Was just wondering if anyone out there has had a good result after ony 3 ipi treatments.  My husband has had a rare side effect that put him in acute kidney failure. Steroids have brought kidney function back to normal but now they will not do the fourth treatment. Scans on monday and we fid out where we are on Wednesday.

    Viewing 11 reply threads
    • Replies
        Tina D
        Participant

          Hi there… I was only able to complete 3 ipi treatments due to an autoimmune side effect causing pituitary inflammation. My first scans showed significant shrinking. I am due for my 2nd set of scans, and I am feeling well. I will be scheduling those scans in the next week or two ( hubby is recuperating from back surgery) and will be posting then. Have read of others who did not complete all 4 treatments and had a very good response..

          Tina

          Tina D
          Participant

            Hi there… I was only able to complete 3 ipi treatments due to an autoimmune side effect causing pituitary inflammation. My first scans showed significant shrinking. I am due for my 2nd set of scans, and I am feeling well. I will be scheduling those scans in the next week or two ( hubby is recuperating from back surgery) and will be posting then. Have read of others who did not complete all 4 treatments and had a very good response..

            Tina

              ljhncj12345
              Participant

                Thank You your response helps.

                ljhncj12345
                Participant

                  Thank You your response helps.

                  ljhncj12345
                  Participant

                    Thank You your response helps.

                  Tina D
                  Participant

                    Hi there… I was only able to complete 3 ipi treatments due to an autoimmune side effect causing pituitary inflammation. My first scans showed significant shrinking. I am due for my 2nd set of scans, and I am feeling well. I will be scheduling those scans in the next week or two ( hubby is recuperating from back surgery) and will be posting then. Have read of others who did not complete all 4 treatments and had a very good response..

                    Tina

                    jim Breitfeller
                    Participant
                      I only did one 15mg/Kg dose of anti-ctla-4. That was in 2006.
                      Jimmy b
                      jim Breitfeller
                      Participant
                        I only did one 15mg/Kg dose of anti-ctla-4. That was in 2006.
                        Jimmy b
                        jim Breitfeller
                        Participant
                          I only did one 15mg/Kg dose of anti-ctla-4. That was in 2006.
                          Jimmy b
                          Jim M.
                          Participant

                            Hi,

                              I, Like Tina had hypothysitis or compromised pituitary function. I got this after 4 treatments. I went into the trial with resected melanoma. Through immune assays on my blood Yervoy gave me a proliferation of T cells. My doc. was thrilled and said he saw that kind of reponse in 10 to 15% of his patients. I'm on a hormone replacement, probably for life. Since surgery I've been NED for 5.5 years. Since Yervoy, 4.5. years.

                            God Bless,

                             Jim M.

                            Jim M.
                            Participant

                              Hi,

                                I, Like Tina had hypothysitis or compromised pituitary function. I got this after 4 treatments. I went into the trial with resected melanoma. Through immune assays on my blood Yervoy gave me a proliferation of T cells. My doc. was thrilled and said he saw that kind of reponse in 10 to 15% of his patients. I'm on a hormone replacement, probably for life. Since surgery I've been NED for 5.5 years. Since Yervoy, 4.5. years.

                              God Bless,

                               Jim M.

                              Jim M.
                              Participant

                                Hi,

                                  I, Like Tina had hypothysitis or compromised pituitary function. I got this after 4 treatments. I went into the trial with resected melanoma. Through immune assays on my blood Yervoy gave me a proliferation of T cells. My doc. was thrilled and said he saw that kind of reponse in 10 to 15% of his patients. I'm on a hormone replacement, probably for life. Since surgery I've been NED for 5.5 years. Since Yervoy, 4.5. years.

                                God Bless,

                                 Jim M.

                                eric w
                                Participant

                                  Hi.. I have a question for Tina D or anyone who has had a reaction that required steroids/hermones….does this exclude you from PD-1 trials? Thanks

                                  eric w
                                  Participant

                                    Hi.. I have a question for Tina D or anyone who has had a reaction that required steroids/hermones….does this exclude you from PD-1 trials? Thanks

                                    eric w
                                    Participant

                                      Hi.. I have a question for Tina D or anyone who has had a reaction that required steroids/hermones….does this exclude you from PD-1 trials? Thanks

                                  Viewing 11 reply threads
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