IPI vs Interferon Clinic Trial

There are a lot of trials for stage 3, if I had it all over to do again I would have gone into a trial. I did interferon but only lasted 13 of the high dose infusions. I’ve read that they are trying to stop disease before progression after surgery and ipi is one of those drugs they’re looking at. Ipi doesn’t have the side effects like interferon and since its approved and used in stage 4 I would go for it!! There’s also the BRAF and MEK inhibitor trials that are looking at stage 3 patients to enroll.
Wishing you the best!

I'm in this trial and was fortunate enough to get the low dose ipi, so far I've had 2 infusions and zero side effects. I was extremely stressed out until I was registered for the trial and randomized into a category, because I can't stand not knowing, but melanoma in itself is a lesson that we can't control everything 🙂 This is your decision and your decision only, but if you were already willing to do interferon, I would say that the trial is worth a shot! I hope that one day soon ipi will be available at an earlier stage, without the gamble of a clinical trial.

Good luck!

I'm in this trial and was fortunate enough to get the low dose ipi, so far I've had 2 infusions and zero side effects. I was extremely stressed out until I was registered for the trial and randomized into a category, because I can't stand not knowing, but melanoma in itself is a lesson that we can't control everything 🙂 This is your decision and your decision only, but if you were already willing to do interferon, I would say that the trial is worth a shot! I hope that one day soon ipi will be available at an earlier stage, without the gamble of a clinical trial.

Good luck!

I'm in this trial and was fortunate enough to get the low dose ipi, so far I've had 2 infusions and zero side effects. I was extremely stressed out until I was registered for the trial and randomized into a category, because I can't stand not knowing, but melanoma in itself is a lesson that we can't control everything 🙂 This is your decision and your decision only, but if you were already willing to do interferon, I would say that the trial is worth a shot! I hope that one day soon ipi will be available at an earlier stage, without the gamble of a clinical trial.

Good luck!

I just wanted to clear this up when you say that ipi doesn't have the side effects that interferon has. My husband was on the ipi/interferon trial and recieved the high does ipi ( at the time the low dose ipi wasn't part of the trial). After dose number 2 my husband was taken to the ER in severe pain. He had very bad colitis (early studies of ipi show that some people died of colitis that were taking ipi). He lost 40 pounds, could not keep food or any liquids down and was hospitalized for 6 days.He had fever, chills, and body aches even after the first dose. Now, with that being said, every person is different and can have diff side effects and some ppl may experience very little side effects.  I think ipi is a very good thing for melanoma and i think this is a good trial. I just wanted to clear that up about it having less or fewer side effects than interferon because it can have just as many if not more severe side effects. My husband has also taken interferon as well.

 

 

Mandi

I just wanted to clear this up when you say that ipi doesn't have the side effects that interferon has. My husband was on the ipi/interferon trial and recieved the high does ipi ( at the time the low dose ipi wasn't part of the trial). After dose number 2 my husband was taken to the ER in severe pain. He had very bad colitis (early studies of ipi show that some people died of colitis that were taking ipi). He lost 40 pounds, could not keep food or any liquids down and was hospitalized for 6 days.He had fever, chills, and body aches even after the first dose. Now, with that being said, every person is different and can have diff side effects and some ppl may experience very little side effects.  I think ipi is a very good thing for melanoma and i think this is a good trial. I just wanted to clear that up about it having less or fewer side effects than interferon because it can have just as many if not more severe side effects. My husband has also taken interferon as well.

 

 

Mandi

I just wanted to clear this up when you say that ipi doesn't have the side effects that interferon has. My husband was on the ipi/interferon trial and recieved the high does ipi ( at the time the low dose ipi wasn't part of the trial). After dose number 2 my husband was taken to the ER in severe pain. He had very bad colitis (early studies of ipi show that some people died of colitis that were taking ipi). He lost 40 pounds, could not keep food or any liquids down and was hospitalized for 6 days.He had fever, chills, and body aches even after the first dose. Now, with that being said, every person is different and can have diff side effects and some ppl may experience very little side effects.  I think ipi is a very good thing for melanoma and i think this is a good trial. I just wanted to clear that up about it having less or fewer side effects than interferon because it can have just as many if not more severe side effects. My husband has also taken interferon as well.

 

 

Mandi

I just wanted to clear this up when you say that ipi doesn't have the side effects that interferon has. My husband was on the ipi/interferon trial and recieved the high does ipi ( at the time the low dose ipi wasn't part of the trial). After dose number 2 my husband was taken to the ER in severe pain. He had very bad colitis (early studies of ipi show that some people died of colitis that were taking ipi). He lost 40 pounds, could not keep food or any liquids down and was hospitalized for 6 days.He had fever, chills, and body aches even after the first dose. Now, with that being said, every person is different and can have diff side effects and some ppl may experience very little side effects.  I think ipi is a very good thing for melanoma and i think this is a good trial. I just wanted to clear that up about it having less or fewer side effects than interferon because it can have just as many if not more severe side effects. My husband has also taken interferon as well.

 

 

Mandi

I just wanted to clear this up when you say that ipi doesn't have the side effects that interferon has. My husband was on the ipi/interferon trial and recieved the high does ipi ( at the time the low dose ipi wasn't part of the trial). After dose number 2 my husband was taken to the ER in severe pain. He had very bad colitis (early studies of ipi show that some people died of colitis that were taking ipi). He lost 40 pounds, could not keep food or any liquids down and was hospitalized for 6 days.He had fever, chills, and body aches even after the first dose. Now, with that being said, every person is different and can have diff side effects and some ppl may experience very little side effects.  I think ipi is a very good thing for melanoma and i think this is a good trial. I just wanted to clear that up about it having less or fewer side effects than interferon because it can have just as many if not more severe side effects. My husband has also taken interferon as well.

 

 

Mandi

I just wanted to clear this up when you say that ipi doesn't have the side effects that interferon has. My husband was on the ipi/interferon trial and recieved the high does ipi ( at the time the low dose ipi wasn't part of the trial). After dose number 2 my husband was taken to the ER in severe pain. He had very bad colitis (early studies of ipi show that some people died of colitis that were taking ipi). He lost 40 pounds, could not keep food or any liquids down and was hospitalized for 6 days.He had fever, chills, and body aches even after the first dose. Now, with that being said, every person is different and can have diff side effects and some ppl may experience very little side effects.  I think ipi is a very good thing for melanoma and i think this is a good trial. I just wanted to clear that up about it having less or fewer side effects than interferon because it can have just as many if not more severe side effects. My husband has also taken interferon as well.

 

 

Mandi

There are a lot of trials for stage 3, if I had it all over to do again I would have gone into a trial. I did interferon but only lasted 13 of the high dose infusions. I’ve read that they are trying to stop disease before progression after surgery and ipi is one of those drugs they’re looking at. Ipi doesn’t have the side effects like interferon and since its approved and used in stage 4 I would go for it!! There’s also the BRAF and MEK inhibitor trials that are looking at stage 3 patients to enroll.
Wishing you the best!

There are a lot of trials for stage 3, if I had it all over to do again I would have gone into a trial. I did interferon but only lasted 13 of the high dose infusions. I’ve read that they are trying to stop disease before progression after surgery and ipi is one of those drugs they’re looking at. Ipi doesn’t have the side effects like interferon and since its approved and used in stage 4 I would go for it!! There’s also the BRAF and MEK inhibitor trials that are looking at stage 3 patients to enroll.
Wishing you the best!