› Forums › General Melanoma Community › Interferon treatment terminated after 3 weeks of IV portion due to elevated liver function and low neutraphils
- This topic has 6 replies, 3 voices, and was last updated 12 years, 9 months ago by nicoli.
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- August 8, 2011 at 1:48 am
I have done a number of searches and have been unable to find any others who have encountered this, but am sure there are. If so – I'd like to hear from you.
I have done a number of searches and have been unable to find any others who have encountered this, but am sure there are. If so – I'd like to hear from you.
I started the high dose interferon June 22. First week labs showed elevated liver function and low neutraphils – both outside of the acceptable range, so oncologist put me on a 1 week break and reduced the dose by half. I was put on 1 week breaks after 2nd week and 3rd week, again because my neutraphils were too low. Throughout, I was generally feeling fairly well, considering some of the side effects others have reported. When I went in to see the oncologist last week he advised that he is terminating the interferon treatment as he doesn't feel it is safe, and that I will get into trouble very quickly once I start the injections. I was surprised and disappointed…I know many don't complete the year, but I hadn't heard of anyone who wasn't able to get through at least the high dose round. Has anyone else encountered this? Are there any other options for me other than wait and watch?
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- August 8, 2011 at 7:11 am
Interferon is a very old treatment for melanoma and its use is controversial. As you
have discovered, it has significant toxicity. This can cause serious side effects in
some patients, so it was wise for your oncologist to stop the treatment at an early
stage.Have you considered Leukine (GM-CSF)? This has been found to change the nature
of melanoma in some people, making any new tumours more manageable with
surgery. See:
http://www.melanoma.org/community/mpip-melanoma-patients-information-page/ned-stage-iv-and-gm-csf-leukineHope this helps.
Frank from Australia
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- August 8, 2011 at 7:11 am
Interferon is a very old treatment for melanoma and its use is controversial. As you
have discovered, it has significant toxicity. This can cause serious side effects in
some patients, so it was wise for your oncologist to stop the treatment at an early
stage.Have you considered Leukine (GM-CSF)? This has been found to change the nature
of melanoma in some people, making any new tumours more manageable with
surgery. See:
http://www.melanoma.org/community/mpip-melanoma-patients-information-page/ned-stage-iv-and-gm-csf-leukineHope this helps.
Frank from Australia
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- August 10, 2011 at 4:33 pm
i often stopped the INF and restarted at a lower dose due to certain changes in blood work, finally stopping after 10 months. INF is an out-dated durg for mel, but for many at stage 3 there is nothing else to be done. Alot of onc's dont ude INF anymore but the ones that do, make sure that it isnt doing more damage than good.
Talk to your doctor about other drugs or trials that may be available for you stage.
Good luck.
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- August 10, 2011 at 4:33 pm
i often stopped the INF and restarted at a lower dose due to certain changes in blood work, finally stopping after 10 months. INF is an out-dated durg for mel, but for many at stage 3 there is nothing else to be done. Alot of onc's dont ude INF anymore but the ones that do, make sure that it isnt doing more damage than good.
Talk to your doctor about other drugs or trials that may be available for you stage.
Good luck.
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- August 10, 2011 at 6:33 pm
Hi,
I did interrferon last year for exactly 2 days. I experienced what my onc called a psychotic episode and it was stopped immediately. From the outset my one said she didn't think it would do any good but I could try if I wanted. My second onc does not recommend it or would even have allowed me to start it. It is an old poison, doesn't do any good and is just to make you feel like you are doing something.
Why put poison in your system for no reason and possibly weaken your system for when you really need the health and strength?
Nicki, Stage 3b
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- August 10, 2011 at 6:33 pm
Hi,
I did interrferon last year for exactly 2 days. I experienced what my onc called a psychotic episode and it was stopped immediately. From the outset my one said she didn't think it would do any good but I could try if I wanted. My second onc does not recommend it or would even have allowed me to start it. It is an old poison, doesn't do any good and is just to make you feel like you are doing something.
Why put poison in your system for no reason and possibly weaken your system for when you really need the health and strength?
Nicki, Stage 3b
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