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Good morning to you all.
My mom started opdivo/ yervoy 3 weeks ago after progression on Taf/Mek. She got terrible pain where her bone lesions are. She has not had any pain there before. We are hoping that it is a good sign. After couple of days, the pain was gone. But she can feel that her tumors in her breast are getting bigger and it hurts. But that is maybe pseudo progression? Also, the doctor refuses surgery and my mom can just feel the lumps getting bigger everyday. Why is that? Also, is it good to use radiation on the bones and where the tumors are in the breast?
She has 3 infusions left with the combo and then just nivolumab. When does the immunotherapy start to kick in? Sorry about all the questions, I just need to hear that even though she feels the tumors get bigger, they can get smaller and she can get NED !
I am sorry she is in pain. I think it is pretty common to start drugs first and get them working in the body and then continue tumor removal and or radiation or all those things at the same time. Surgery and radiation can be layered on top of the immunotherapy when the tumor become painful. I’d think the drugs need a little more time to work.
Thank you for your reply. She is in so much pain. She will get her 2. infusion of opdivo/yervoy on wednesday and hopefully the can radiate her breast asap. The strongest painkillers doesnt work on the pain 🙁
Thank you for responding. She is in excruciating discomfort. She will receive her two bike race.
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