HELP
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

HELP

› Forums › General Melanoma Community › HELP

  • Post
    • July 25, 2012 at 1:25 am
    bikerwife
    Participant
    Has anyone had gamma knife more than once. We had it in feb for 5 mets and they are gone. We have 2 new ones that will be gamma knifed on aug 13and I’m scared of having this procedure done again. Our dr told me to stop worrying that they got them the first time and can get them again. I do feel kinda at ease about.

    Also he’s still taking zelobraf which is working wonderful all tumors we could see are almost gone. Why doesn’t it work in brain.

    Thanks for the help

    Has anyone had gamma knife more than once. We had it in feb for 5 mets and they are gone. We have 2 new ones that will be gamma knifed on aug 13and I’m scared of having this procedure done again. Our dr told me to stop worrying that they got them the first time and can get them again. I do feel kinda at ease about.

    Also he’s still taking zelobraf which is working wonderful all tumors we could see are almost gone. Why doesn’t it work in brain.

    Thanks for the help

Viewing 5 reply threads
  • Replies
      • July 25, 2012 at 2:56 am
      MichaelFL
      Participant

      I can't answer your question about Gamma knife, but I believe Zelboraf does not cross what is called the Blood Brain Barrier (BBB).

      The blood–brain barrier (BBB) is a separation of circulating blood from the brain. Only certain small molecules can cross it. The molecules of Zelboraf are too big.

      • July 25, 2012 at 2:56 am
      MichaelFL
      Participant

      I can't answer your question about Gamma knife, but I believe Zelboraf does not cross what is called the Blood Brain Barrier (BBB).

      The blood–brain barrier (BBB) is a separation of circulating blood from the brain. Only certain small molecules can cross it. The molecules of Zelboraf are too big.

      • July 25, 2012 at 2:56 am
      MichaelFL
      Participant

      I can't answer your question about Gamma knife, but I believe Zelboraf does not cross what is called the Blood Brain Barrier (BBB).

      The blood–brain barrier (BBB) is a separation of circulating blood from the brain. Only certain small molecules can cross it. The molecules of Zelboraf are too big.

      • July 25, 2012 at 4:11 am
      James from Sydney
      Participant

      Ask your Doc to review new data released on Dabrafenib another BRAF drug apparently it has shown positive results with Brain Mets. Here is the link

      http://www.reuters.com/article/2012/05/18/us-melanoma-gsk-dabrafenib-idUSBRE84H01G20120518

      best wishes

      James

      • July 25, 2012 at 4:11 am
      James from Sydney
      Participant

      Ask your Doc to review new data released on Dabrafenib another BRAF drug apparently it has shown positive results with Brain Mets. Here is the link

      http://www.reuters.com/article/2012/05/18/us-melanoma-gsk-dabrafenib-idUSBRE84H01G20120518

      best wishes

      James

      • July 25, 2012 at 4:11 am
      James from Sydney
      Participant

      Ask your Doc to review new data released on Dabrafenib another BRAF drug apparently it has shown positive results with Brain Mets. Here is the link

      http://www.reuters.com/article/2012/05/18/us-melanoma-gsk-dabrafenib-idUSBRE84H01G20120518

      best wishes

      James

Viewing 5 reply threads
  • You must be logged in to reply to this topic.
About the MRF Patient Forum

The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

Popular Topics